# Niacinamide and gluconolactone

Page: https://lovi.care/skincare/uk/ingredients/niacinamide-and-gluconolactone

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Depends on the strength

Use them together because [niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide) strengthens skin while [gluconolactone](https://lovi.care/skincare/uk/ingredients/gluconolactone) smooths texture. This pair works well together to improve skin texture without causing irritation. The shopper can use a lower strength if any dryness occurs.

- [All about niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide)
- [All about gluconolactone](https://lovi.care/skincare/uk/ingredients/gluconolactone)

### [Niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide) products

- [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit
- [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [£8.29 at Amazon](https://www.amazon.co.uk/dp/B07C5SKVL7?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/uk/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [£13.00 at Amazon](https://www.amazon.co.uk/dp/B09ZF9X3R1?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/uk/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [£16.60 at Amazon](https://www.amazon.co.uk/dp/B00BH4LNWM?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/uk/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [£16.81 at Amazon](https://www.amazon.co.uk/dp/B07PK2P2XB?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/uk/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [£11.18 at Amazon](https://www.amazon.co.uk/dp/B0B2RM68G2?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/uk/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [£24.99 at Amazon](https://www.amazon.co.uk/dp/B0012J30LY?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CeraVe Resurfacing Retinol Serum](https://lovi.care/skincare/uk/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [£15.64 at Amazon](https://www.amazon.co.uk/dp/B0B913JC2W?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/uk/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [£11.29 at Amazon](https://www.amazon.co.uk/dp/B07C5XYT19?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Medicube PDRN Pink Peptide Serum](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [£13.80 at Amazon](https://www.amazon.co.uk/dp/B0G29RKZ1H?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CeraVe Renewing SA Cleanser](https://lovi.care/skincare/uk/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [£9.59 at Amazon](https://www.amazon.co.uk/dp/B00U1YCRD8?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Medicube Collagen Jelly Cream](https://lovi.care/skincare/uk/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [£14.80 at Amazon](https://www.amazon.co.uk/dp/B0CM2PPNMW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

### [Gluconolactone](https://lovi.care/skincare/uk/ingredients/gluconolactone) products

- [EADEM Cashmere Peel](https://lovi.care/skincare/uk/p/eadem/cashmere-peel/for/oily-skin) — Average fit
- [Kiehl's Hydro-Plumping Serum Concentrate](https://lovi.care/skincare/uk/p/kiehl-s/hydro-plumping-serum-concentrate/for/dry-skin) — Superior fit — [£57.00 at Amazon](https://www.amazon.co.uk/dp/B0GQJYKVXN?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [StriVectin Daily Reveal Exfoliating Pads](https://lovi.care/skincare/uk/p/strivectin/daily-reveal-exfoliating-pads/for/oily-skin) — Average fit
- [Hero Cosmetics Pore Release Blackhead Clearing Solution](https://lovi.care/skincare/uk/p/hero-cosmetics/pore-release-blackhead-clearing-solution/for/combination-skin) — Superior fit
- [Some By Mi AHA-BHA-PHA 30 Days Miracle Acne Clear Foam](https://lovi.care/skincare/uk/p/some-by-mi/aha-bha-pha-30-days-miracle-acne-clear-foam/for/oily-acne-prone-skin) — High fit — [£14.00 at Amazon](https://www.amazon.co.uk/dp/B07Q34Y99J?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [OLEHENRIKSEN Truth Juice Daily Cleanser](https://lovi.care/skincare/uk/p/olehenriksen/truth-juice-daily-cleanser/for/oily-acne-prone-skin) — High fit
- [Farmacy Brighten Up 3% TXA](https://lovi.care/skincare/uk/p/farmacy/brighten-up-3-txa/for/acne-prone-skin) — Average fit — [£16.00 at Amazon](https://www.amazon.co.uk/dp/B0CNS5NYXX?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Bright Boost Gel Cream](https://lovi.care/skincare/uk/p/neutrogena/bright-boost-gel-cream/for/acne-prone-skin) — High fit
- [Medik8 Press & Glow](https://lovi.care/skincare/uk/p/medik8/press-and-glow/for/dry-skin) — Superior fit — [£29.00 at Amazon](https://www.amazon.co.uk/dp/B093RPJY32?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [AXIS-Y PHA Resurfacing Glow Peel](https://lovi.care/skincare/uk/p/axis-y/pha-resurfacing-glow-peel/for/mature-skin) — Superior fit — [£12.65 at Amazon](https://www.amazon.co.uk/dp/B0B5ZLYP15?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [RNW Der. Clear AHA BHA PHA Peeling Mask](https://lovi.care/skincare/uk/p/rnw/der-clear-aha-bha-pha-peeling-mask/for/combination-skin) — Superior fit
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/uk/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/dry-sensitive-skin) — Superior fit — [£34.00 at Amazon](https://www.amazon.co.uk/dp/B0HFYYH9D1?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use niacinamide and gluconolactone together?

Yes, you can use [niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide) and [gluconolactone](https://lovi.care/skincare/uk/ingredients/gluconolactone) together depending on the strength, and products like The INKEY List PHA Toner and BYOMA Clarifying [Serum](https://lovi.care/skincare/uk/ingredients/serum) feature both ingredients. Combining them helps improve cell renewal without irritation because niacinamide supports the barrier while mild acids smooth texture.

### Which goes first, niacinamide or gluconolactone?

Yes, you can use niacinamide and gluconolactone together depending on the strength, as this combination improves cell renewal without irritation. You can find both ingredients in products like Face Reality sal-C toner, CeraVe Blemish Control Cleanser, SKIN1004 Madagascar [Centella](https://lovi.care/skincare/uk/ingredients/centella-asiatica) Toning Toner, The INKEY List PHA Toner, BYOMA Clarifying Serum, and Biologique Recherche Lotion P50V.

### Are niacinamide and gluconolactone good for sensitive skin?

Yes, niacinamide and gluconolactone are good for sensitive skin depending on the strength, as niacinamide supports the skin barrier while mild acids help smooth texture without irritation. You can find this combination in products like The INKEY List PHA Toner, BYOMA Clarifying Serum, and CeraVe Blemish Control Cleanser.

## Research on niacinamide and gluconolactone

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023

## Other combinations

- Depends on the strength: [Retinol and niacinamide](https://lovi.care/skincare/uk/ingredients/retinol-and-niacinamide)
- Depends on the strength: [AHA blend glycolic and citric acids and niacinamide](https://lovi.care/skincare/uk/ingredients/aha-blend-glycolic-and-citric-acids-and-niacinamide)
- Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-citric-acid)
- Depends on the strength: [Glycolic acid and niacinamide](https://lovi.care/skincare/uk/ingredients/glycolic-acid-and-niacinamide)
- Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-lactic-acid)
- Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-mandelic-acid)
- Depends on the strength: [Niacinamide and salicylic acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-salicylic-acid)
- Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-lactobionic-acid)
- Work well together: [Niacinamide and cholesterol](https://lovi.care/skincare/uk/ingredients/niacinamide-and-cholesterol)
- Work well together: [Niacinamide and lauric acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-lauric-acid)
- Work well together: [Niacinamide and linoleic acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-linoleic-acid)
- Work well together: [Niacinamide and tri-ceramide complex](https://lovi.care/skincare/uk/ingredients/niacinamide-and-tri-ceramide-complex)
- Depends on the strength: [Adapalene and niacinamide](https://lovi.care/skincare/uk/ingredients/adapalene-and-niacinamide)
- Depends on the strength: [Niacinamide and granactive retinoid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-granactive-retinoid)
- Depends on the strength: [Niacinamide and hydroxypinacolone retinoate](https://lovi.care/skincare/uk/ingredients/niacinamide-and-hydroxypinacolone-retinoate)
- Depends on the strength: [Niacinamide and pro-retinol](https://lovi.care/skincare/uk/ingredients/niacinamide-and-pro-retinol)
- Depends on the strength: [Niacinamide and retinal](https://lovi.care/skincare/uk/ingredients/niacinamide-and-retinal)
- Depends on the strength: [Niacinamide and retinoid blend](https://lovi.care/skincare/uk/ingredients/niacinamide-and-retinoid-blend)
- Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/uk/ingredients/niacinamide-and-tretinoin)
- Depends on the strength: [Niacinamide and vitamin A](https://lovi.care/skincare/uk/ingredients/niacinamide-and-vitamin-a)
- Work well together: [Gluconolactone and hyaluronic acid](https://lovi.care/skincare/uk/ingredients/gluconolactone-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/uk/ingredients/niacinamide-and-bio-placenta-peptides)
- Depends on the strength: [Niacinamide and collagen peptide](https://lovi.care/skincare/uk/ingredients/niacinamide-and-collagen-peptide)
- Depends on the strength: [Niacinamide and copper peptide](https://lovi.care/skincare/uk/ingredients/niacinamide-and-copper-peptide)
- Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/uk/ingredients/niacinamide-and-hexapeptide)
- Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/uk/ingredients/niacinamide-and-hexapeptide-9)
- Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/uk/ingredients/niacinamide-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Niacinamide and palmitoyl tripeptide-1](https://lovi.care/skincare/uk/ingredients/niacinamide-and-palmitoyl-tripeptide-1)
- Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/uk/ingredients/niacinamide-and-peptide-rich-plasma)
- Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/uk/ingredients/niacinamide-and-triple-peptide-blend)
- Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-hyaluronic-acid)
- Work well together: [AHA blend glycolic and citric acids and gluconolactone](https://lovi.care/skincare/uk/ingredients/aha-blend-glycolic-and-citric-acids-and-gluconolactone)
- Work well together: [Gluconolactone and citric acid](https://lovi.care/skincare/uk/ingredients/gluconolactone-and-citric-acid)
- Work well together: [Glycolic acid and gluconolactone](https://lovi.care/skincare/uk/ingredients/glycolic-acid-and-gluconolactone)
- Work well together: [Lactic acid and gluconolactone](https://lovi.care/skincare/uk/ingredients/lactic-acid-and-gluconolactone)
- Work well together: [Mandelic acid and gluconolactone](https://lovi.care/skincare/uk/ingredients/mandelic-acid-and-gluconolactone)
- Work well together: [Vitamin C and gluconolactone](https://lovi.care/skincare/uk/ingredients/vitamin-c-and-gluconolactone)
- Work well together: [Niacinamide and bakuchiol](https://lovi.care/skincare/uk/ingredients/niacinamide-and-bakuchiol)
- Work well together: [Niacinamide and zinc](https://lovi.care/skincare/uk/ingredients/niacinamide-and-zinc)
- Work well together: [Niacinamide and zinc gluconate](https://lovi.care/skincare/uk/ingredients/niacinamide-and-zinc-gluconate)
- Work well together: [Niacinamide and zinc oxide](https://lovi.care/skincare/uk/ingredients/niacinamide-and-zinc-oxide)
- Work well together: [Niacinamide and zinc sulfate](https://lovi.care/skincare/uk/ingredients/niacinamide-and-zinc-sulfate)
- Work well together: [Benzoyl peroxide and niacinamide](https://lovi.care/skincare/uk/ingredients/benzoyl-peroxide-and-niacinamide)
- Work well together: [Salicylic acid and gluconolactone](https://lovi.care/skincare/uk/ingredients/salicylic-acid-and-gluconolactone)
- Keep them apart: [Niacinamide and lipohydroxy acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-lipohydroxy-acid)
- Work well together: [Ferulic acid and niacinamide](https://lovi.care/skincare/uk/ingredients/ferulic-acid-and-niacinamide)
- Work well together: [Green tea and niacinamide](https://lovi.care/skincare/uk/ingredients/green-tea-and-niacinamide)
- Work well together: [Niacinamide and vitamin E](https://lovi.care/skincare/uk/ingredients/niacinamide-and-vitamin-e)
- Keep them apart: [Niacinamide and isopropyl alcohol](https://lovi.care/skincare/uk/ingredients/niacinamide-and-isopropyl-alcohol)
- Work well together: [Niacinamide and ascorbyl glucoside](https://lovi.care/skincare/uk/ingredients/niacinamide-and-ascorbyl-glucoside)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/niacinamide-and-gluconolactone
- United Kingdom: https://lovi.care/skincare/uk/ingredients/niacinamide-and-gluconolactone (this page)
- Ireland: https://lovi.care/skincare/ie/ingredients/niacinamide-and-gluconolactone
- Germany: https://lovi.care/skincare/de/ingredients/niacinamide-and-gluconolactone
- France: https://lovi.care/skincare/fr/ingredients/niacinamide-and-gluconolactone
- Italy: https://lovi.care/skincare/it/ingredients/niacinamide-and-gluconolactone
- Netherlands: https://lovi.care/skincare/nl/ingredients/niacinamide-and-gluconolactone
- Spain: https://lovi.care/skincare/es/ingredients/niacinamide-and-gluconolactone
- Canada: https://lovi.care/skincare/ca/ingredients/niacinamide-and-gluconolactone
- Australia: https://lovi.care/skincare/au/ingredients/niacinamide-and-gluconolactone
- Singapore: https://lovi.care/skincare/sg/ingredients/niacinamide-and-gluconolactone
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/niacinamide-and-gluconolactone
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/niacinamide-and-gluconolactone