# Acetyl hexapeptide-3 and citric acid

Page: https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-citric-acid

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Keep them apart

Use them at different times of day, applying the acid first and the peptide second, because acid breaks down the peptide. [Citric acid](https://lovi.care/skincare/uk/ingredients/citric-acid) makes the skin too acidic, which ruins [acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3) and stops it from smoothing fine lines. You can use them in separate routines, like one in the morning and one at night.

- [All about acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3)
- [All about citric acid](https://lovi.care/skincare/uk/ingredients/citric-acid)

### [Acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [£28.90 at Amazon](https://www.amazon.co.uk/dp/B0C9DXGXZ3?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit — [£12.72 at Amazon](https://www.amazon.co.uk/dp/B0BLHW7JZM?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Medik8 Liquid Peptides](https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [£51.15 at Amazon](https://www.amazon.co.uk/dp/B0DDY3D3QW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [La Mer The Treatment Lotion](https://lovi.care/skincare/uk/p/la-mer/the-treatment-lotion/for/mature-skin) — Superior fit — [£209.56 at Amazon](https://www.amazon.co.uk/dp/B076ZQ7YVB?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Rhode Peptide Glazing Fluid](https://lovi.care/skincare/uk/p/rhode/peptide-glazing-fluid/for/mature-skin) — High fit — [£35.00 at Amazon](https://www.amazon.co.uk/dp/B0GNNW5QV3?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/uk/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit — [£7.36 at Amazon](https://www.amazon.co.uk/dp/B072JH13CD?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Good Molecules Super Peptide Serum](https://lovi.care/skincare/uk/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B091MTKS35?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/uk/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [£46.87 at Amazon](https://www.amazon.co.uk/dp/B09FG9W2LM?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [La Mer The Renewal Oil](https://lovi.care/skincare/uk/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [£175.50 at Amazon](https://www.amazon.co.uk/dp/B01MTQKM02?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Estée Lauder Micro Essence Treatment Lotion](https://lovi.care/skincare/uk/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit — [£42.00 at Amazon](https://www.amazon.co.uk/dp/B0BB44W3QP?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/uk/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit
- [La Mer The Eye Concentrate](https://lovi.care/skincare/uk/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [£199.00 at Amazon](https://www.amazon.co.uk/dp/B00438A000?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

### [Citric acid](https://lovi.care/skincare/uk/ingredients/citric-acid) products

- [The Ordinary Salicylic Acid 2% Solution](https://lovi.care/skincare/uk/p/the-ordinary/salicylic-acid-2-solution/for/dry-skin) — Average fit — [£4.88 at Amazon](https://www.amazon.co.uk/dp/B0C3PCJ6SD?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Dr. Bronner's Pure-Castile Liquid Soap (Baby Unscented)](https://lovi.care/skincare/uk/p/dr-bronner-s/pure-castile-liquid-soap-baby-unscented/for/dry-sensitive-skin) — Average fit
- [Thayers Hydrating Milky Toner](https://lovi.care/skincare/uk/p/thayers/hydrating-milky-toner/for/dry-skin) — High fit — [£22.50 at Amazon](https://www.amazon.co.uk/dp/B0BQCRH6D8?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Seven Minerals Organic Aloe Vera Gel](https://lovi.care/skincare/uk/p/seven-minerals/organic-aloe-vera-gel/for/dry-sensitive-skin) — Average fit
- [SkinCeuticals Blemish + Age Defense](https://lovi.care/skincare/uk/p/skinceuticals/blemish-age-defense/for/oily-skin) — Superior fit — [£114.00 at Lookfantastic](https://www.lookfantastic.com/p/skinceuticals-blemish-and-age-defense-corrective-serum-30ml/11705708/)
- [Naturie Hatomugi Skin Conditioner](https://lovi.care/skincare/uk/p/naturie/hatomugi-skin-conditioner/for/sensitive-skin) — High fit
- [E45 Cream](https://lovi.care/skincare/uk/p/e45/cream/for/dry-skin) — High fit — [£2.75 at Amazon](https://www.amazon.co.uk/dp/B002ISB9NO?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [NATURIUM BHA Liquid Exfoliant 2%](https://lovi.care/skincare/uk/p/naturium/bha-liquid-exfoliant-2/for/oily-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B011U9M3MW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Dr. Sam's Flawless Cleanser](https://lovi.care/skincare/uk/p/dr-sam-s/flawless-cleanser/for/dry-skin) — High fit
- [Kiehl's Calendula Deep Cleansing Foaming Face Wash](https://lovi.care/skincare/uk/p/kiehl-s/calendula-deep-cleansing-foaming-face-wash/for/oily-skin) — Superior fit — [£24.75 at Amazon](https://www.amazon.co.uk/dp/B00O19W9UA?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Hydro Boost Micellar Water](https://lovi.care/skincare/uk/p/neutrogena/hydro-boost-micellar-water/for/dark-spots) — Average fit — [£7.02 at Amazon](https://www.amazon.co.uk/dp/B07KWK41VJ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Garnier SkinActive Blackhead Eliminating Scrub](https://lovi.care/skincare/uk/p/garnier-skinactive/blackhead-eliminating-scrub/for/oily-skin) — Low fit — [£4.00 at Amazon](https://www.amazon.co.uk/dp/B01NAN5FZG?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use acetyl hexapeptide-3 and citric acid together?

Keep [acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3) and [citric acid](https://lovi.care/skincare/uk/ingredients/citric-acid) apart and use them in separate steps or routines, such as alternating between morning and evening, because the acidic environment of citric acid can destabilize peptide bonds and reduce their effectiveness.

### Which goes first, acetyl hexapeptide-3 or citric acid?

Keep acetyl hexapeptide-3 and citric acid apart by using them in separate steps or routines, such as morning and evening separation. The acidic environment of citric acid destabilizes peptide bonds and may reduce the bioactivity of acetyl hexapeptide-3 if they are combined.

### Are acetyl hexapeptide-3 and citric acid good for sensitive skin?

Keep acetyl hexapeptide-3 and citric acid apart because the low-pH environment of citric acid may destabilize the peptide and reduce its activity. Sensitive skin should especially avoid combining them in the same routine.

## Research on acetyl hexapeptide-3 and citric acid

- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013

## Other combinations

- Keep them apart: [Benzoyl peroxide and citric acid](https://lovi.care/skincare/uk/ingredients/benzoyl-peroxide-and-citric-acid)
- Keep them apart: [Retinol and citric acid](https://lovi.care/skincare/uk/ingredients/retinol-and-citric-acid)
- Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/uk/ingredients/niacinamide-and-citric-acid)
- Work well together: [Sodium lactate and citric acid](https://lovi.care/skincare/uk/ingredients/sodium-lactate-and-citric-acid)
- Work well together: [Citric acid and tromethamine](https://lovi.care/skincare/uk/ingredients/citric-acid-and-tromethamine)
- Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/adapalene-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid)
- Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/pro-retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/retinal-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-retinoid-blend)
- Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/vitamin-a-and-acetyl-hexapeptide-3)
- Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/liposome-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-microcapsule)
- Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/vitamin-c-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-betaine)
- Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/glycerin-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Work well together: [Betaine and citric acid](https://lovi.care/skincare/uk/ingredients/betaine-and-citric-acid)
- Work well together: [Glycerin and citric acid](https://lovi.care/skincare/uk/ingredients/glycerin-and-citric-acid)
- Depends on the strength: [Hyaluronic acid and citric acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid-and-citric-acid)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/panthenol-and-acetyl-hexapeptide-3)
- Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/bakuchiol-and-acetyl-hexapeptide-3)
- Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/arginine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-gaba)
- Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3)
- Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/taurine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3)
- Keep them apart: [Bio-placenta peptides and citric acid](https://lovi.care/skincare/uk/ingredients/bio-placenta-peptides-and-citric-acid)
- Keep them apart: [Carnosine and citric acid](https://lovi.care/skincare/uk/ingredients/carnosine-and-citric-acid)
- Keep them apart: [Collagen peptide and citric acid](https://lovi.care/skincare/uk/ingredients/collagen-peptide-and-citric-acid)
- Keep them apart: [Copper peptide and citric acid](https://lovi.care/skincare/uk/ingredients/copper-peptide-and-citric-acid)
- Keep them apart: [Hexapeptide and citric acid](https://lovi.care/skincare/uk/ingredients/hexapeptide-and-citric-acid)
- Keep them apart: [Citric acid and hexapeptide-9](https://lovi.care/skincare/uk/ingredients/citric-acid-and-hexapeptide-9)
- Keep them apart: [Citric acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/uk/ingredients/citric-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Citric acid and palmitoyl tripeptide-1](https://lovi.care/skincare/uk/ingredients/citric-acid-and-palmitoyl-tripeptide-1)
- Keep them apart: [Citric acid and peptide-rich plasma](https://lovi.care/skincare/uk/ingredients/citric-acid-and-peptide-rich-plasma)
- Keep them apart: [Citric acid and triple peptide blend](https://lovi.care/skincare/uk/ingredients/citric-acid-and-triple-peptide-blend)
- Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/glycolic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3)
- Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/green-tea-and-acetyl-hexapeptide-3)
- Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/vitamin-e-and-acetyl-hexapeptide-3)
- Keep them apart: [Adapalene and citric acid](https://lovi.care/skincare/uk/ingredients/adapalene-and-citric-acid)
- Keep them apart: [Granactive retinoid and citric acid](https://lovi.care/skincare/uk/ingredients/granactive-retinoid-and-citric-acid)
- Keep them apart: [Hydroxypinacolone retinoate and citric acid](https://lovi.care/skincare/uk/ingredients/hydroxypinacolone-retinoate-and-citric-acid)
- Keep them apart: [Pro-retinol and citric acid](https://lovi.care/skincare/uk/ingredients/pro-retinol-and-citric-acid)
- Keep them apart: [Retinal and citric acid](https://lovi.care/skincare/uk/ingredients/retinal-and-citric-acid)
- Keep them apart: [Retinoid blend and citric acid](https://lovi.care/skincare/uk/ingredients/retinoid-blend-and-citric-acid)
- Keep them apart: [Tretinoin and citric acid](https://lovi.care/skincare/uk/ingredients/tretinoin-and-citric-acid)
- Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and cholesterol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-cholesterol)
- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-phytosterol)
- Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-squalene)
- Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex)
- Work well together: [Gluconolactone and citric acid](https://lovi.care/skincare/uk/ingredients/gluconolactone-and-citric-acid)
- Work well together: [Lactobionic acid and citric acid](https://lovi.care/skincare/uk/ingredients/lactobionic-acid-and-citric-acid)
- Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/salicylic-acid-and-acetyl-hexapeptide-3)
- Work well together: [Cholesterol and citric acid](https://lovi.care/skincare/uk/ingredients/cholesterol-and-citric-acid)
- Work well together: [Citric acid and lauric acid](https://lovi.care/skincare/uk/ingredients/citric-acid-and-lauric-acid)
- Work well together: [Linoleic acid and citric acid](https://lovi.care/skincare/uk/ingredients/linoleic-acid-and-citric-acid)
- Keep them apart: [Citric acid and tri-ceramide complex](https://lovi.care/skincare/uk/ingredients/citric-acid-and-tri-ceramide-complex)
- Work well together: [Arginine and citric acid](https://lovi.care/skincare/uk/ingredients/arginine-and-citric-acid)
- Work well together: [Citric acid and GABA](https://lovi.care/skincare/uk/ingredients/citric-acid-and-gaba)
- Work well together: [Silk amino acids and citric acid](https://lovi.care/skincare/uk/ingredients/silk-amino-acids-and-citric-acid)
- Work well together: [Taurine and citric acid](https://lovi.care/skincare/uk/ingredients/taurine-and-citric-acid)
- Work well together: [Citric acid and theanine](https://lovi.care/skincare/uk/ingredients/citric-acid-and-theanine)
- Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-baking-soda)
- Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-bleach)
- Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide)
- Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol)
- Work well together: [Ferulic acid and citric acid](https://lovi.care/skincare/uk/ingredients/ferulic-acid-and-citric-acid)
- Work well together: [Vitamin E and citric acid](https://lovi.care/skincare/uk/ingredients/vitamin-e-and-citric-acid)
- Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/copper-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and citric acid](https://lovi.care/skincare/uk/ingredients/azelaic-acid-and-citric-acid)
- Keep them apart: [Salicylic acid and citric acid](https://lovi.care/skincare/uk/ingredients/salicylic-acid-and-citric-acid)
- Work well together: [Allantoin and citric acid](https://lovi.care/skincare/uk/ingredients/allantoin-and-citric-acid)
- Work well together: [Citric acid and bisabolol](https://lovi.care/skincare/uk/ingredients/citric-acid-and-bisabolol)
- Work well together: [Panthenol and citric acid](https://lovi.care/skincare/uk/ingredients/panthenol-and-citric-acid)
- Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/magnesium-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-zinc)
- Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/uk/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-protease)
- Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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