# Sesderma vs Taro Page: https://lovi.care/skincare/uk/compare/sesderma-vs-taro The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom. Sesderma and Taro are skincare brands beloved for advanced and targeted [serums](https://lovi.care/skincare/uk/ingredients/serum) with meticulously engineered and carefully crafted formulas. The Spanish enterprise founded in 1989 suits sensitive, hyperpigmented, and aging skin best, whereas the other brand suits sensitive, dry, and combination skin best. Standout items include the Azelac RU Serum for acne-prone skin from the former and the [Tretinoin](https://lovi.care/skincare/uk/ingredients/tretinoin) Cream for acne-prone skin from the latter. Both brands differ through botanical [extracts](https://lovi.care/skincare/uk/ingredients/extract) and active compounds versus reliable daily care for modern routines. Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026. [skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html) This page compares some of the most popular Sesderma and Taro products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pge1343649a7). ### Popular Sesderma vs Taro products #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/uk/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [£26.27 at Amazon](https://www.amazon.co.uk/dp/B00987RKWW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1) #### Taro - [Tretinoin Cream](https://lovi.care/skincare/uk/p/taro/tretinoin-cream/for/combination-skin) — High fit ### Sesderma vs Taro [serums](https://lovi.care/skincare/uk/ingredients/serum) and treatments #### Sesderma - [Azelac RU Serum](https://lovi.care/skincare/uk/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [£26.27 at Amazon](https://www.amazon.co.uk/dp/B00987RKWW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1) #### Taro - [Tretinoin Cream](https://lovi.care/skincare/uk/p/taro/tretinoin-cream/for/combination-skin) — High fit ## Questions and answers ### Sesderma or Taro: which is better? Both brands are a good choice depending on your skin type, as Lovi rates Sesderma's Azelac RU [Serum](https://lovi.care/skincare/uk/ingredients/serum) and Taro's [Tretinoin](https://lovi.care/skincare/uk/ingredients/tretinoin) Cream as a High fit for acne-prone skin. Sesderma's product contains fragrance, while Taro's has no fragrance. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) [The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) ### What is the difference between Sesderma and Taro? Sesderma offers Azelac RU Serum which has a High Lovi fit for skin with dark spots and contains fragrance, whereas Taro offers Tretinoin Cream which is fragrance-free and has a Low fit for dark spots. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) [The New England Journal of Medicine, 1993](https://pubmed.ncbi.nlm.nih.gov/8336752/) ### Which is more affordable, Sesderma or Taro? Neither Sesderma nor Taro has price information provided on this page, so affordability cannot be compared. ### Which causes fewer breakouts, Sesderma or Taro? Both Sesderma and Taro have products on this page that show a High Lovi fit for acne-prone skin, meaning Azelac RU Serum and Tretinoin Cream each help manage breakouts. [Azelaic acid](https://lovi.care/skincare/uk/ingredients/azelaic-acid) helps reduce acne vulgaris, and tretinoin helps treat acne. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/) ### When were Sesderma and Taro founded? Sesderma was founded in 1989 in Spain, while Taro was founded in 1950. ### Which brand has products with fragrance, Sesderma or Taro? Sesderma offers products with fragrance, whereas Taro lists no fragrance in the ingredients for the products on this page. ### How well does Sesderma Azelac RU Serum fit acne-prone skin compared to Taro Tretinoin Cream? Both Sesderma Azelac RU Serum and Taro Tretinoin Cream achieve a High Lovi fit for acne-prone skin. Azelaic acid helps manage acne vulgaris, while tretinoin aids in treating acne conditions. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) [Clinical, Cosmetic and Investigational Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32210603/) ## Research behind their key ingredients - [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000 - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)](https://pubmed.ncbi.nlm.nih.gov/8336752/) Tretinoin · The New England Journal of Medicine, 1993 - [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007 - [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Butylated hydroxytoluene · International Journal of Toxicology, 2002 - [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004 - [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017 - [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019 - [Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne](https://pubmed.ncbi.nlm.nih.gov/32210603/) Tretinoin · Clinical, Cosmetic and Investigational Dermatology, 2020 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007 - [Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study](https://pubmed.ncbi.nlm.nih.gov/34146120/) Tretinoin · Archives of Dermatological Research, 2022 - [Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/35620028/) Tretinoin · International Journal of Women's Dermatology, 2022 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [Nanogel Containing Gamma-Oryzanol-Loaded Nanostructured Lipid Carriers and TiO2/MBBT: A Synergistic Nanotechnological Approach of Potent Natural Antioxidants and Nanosized UV Filters for Skin Protection](https://pubmed.ncbi.nlm.nih.gov/37242453/) Xanthan gum · Pharmaceuticals, 2023 - [Topical application of highly concentrated water-in-oil emulsions: Physiological skin parameters and skin penetration in vivo - A pilot study](https://pubmed.ncbi.nlm.nih.gov/31525444/) Isopropyl myristate · International Journal of Pharmaceutics, 2019 - [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998 - [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025 - [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021 - [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024 ## The brands - Spanish skincare: [Sesderma](https://lovi.care/skincare/uk/brands/sesderma) - Skincare: [Taro](https://lovi.care/skincare/uk/brands/taro) ## More comparisons - [SKIN1004 vs Sesderma](https://lovi.care/skincare/uk/compare/skin1004-vs-sesderma) - [SKIN1004 vs Taro](https://lovi.care/skincare/uk/compare/skin1004-vs-taro) - [Anua vs Sesderma](https://lovi.care/skincare/uk/compare/anua-vs-sesderma) - [Anua vs Taro](https://lovi.care/skincare/uk/compare/anua-vs-taro) - [Medicube vs Sesderma](https://lovi.care/skincare/uk/compare/medicube-vs-sesderma) - [Medicube vs Taro](https://lovi.care/skincare/uk/compare/medicube-vs-taro) - [The Ordinary vs Sesderma](https://lovi.care/skincare/uk/compare/the-ordinary-vs-sesderma) - [The Ordinary vs Taro](https://lovi.care/skincare/uk/compare/the-ordinary-vs-taro) - [Beauty of Joseon vs Sesderma](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-sesderma) - [Beauty of Joseon vs Taro](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-taro) - [COSRX vs Sesderma](https://lovi.care/skincare/uk/compare/cosrx-vs-sesderma) - [COSRX vs Taro](https://lovi.care/skincare/uk/compare/cosrx-vs-taro) - [CeraVe vs Sesderma](https://lovi.care/skincare/uk/compare/cerave-vs-sesderma) - [CeraVe vs Taro](https://lovi.care/skincare/uk/compare/cerave-vs-taro) - [La Roche-Posay vs Sesderma](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-sesderma) - [La Roche-Posay vs Taro](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-taro) - [Dr. Althea vs Sesderma](https://lovi.care/skincare/uk/compare/dr-althea-vs-sesderma) - [Dr. Althea vs Taro](https://lovi.care/skincare/uk/compare/dr-althea-vs-taro) - [Some By Mi vs Sesderma](https://lovi.care/skincare/uk/compare/some-by-mi-vs-sesderma) - [Some By Mi vs Taro](https://lovi.care/skincare/uk/compare/some-by-mi-vs-taro) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/sesderma-vs-taro - United Kingdom: https://lovi.care/skincare/uk/compare/sesderma-vs-taro (this page) - Ireland: https://lovi.care/skincare/ie/compare/sesderma-vs-taro - Germany: https://lovi.care/skincare/de/compare/sesderma-vs-taro - France: https://lovi.care/skincare/fr/compare/sesderma-vs-taro - Italy: https://lovi.care/skincare/it/compare/sesderma-vs-taro - Netherlands: https://lovi.care/skincare/nl/compare/sesderma-vs-taro - Spain: https://lovi.care/skincare/es/compare/sesderma-vs-taro - Canada: https://lovi.care/skincare/ca/compare/sesderma-vs-taro - Australia: https://lovi.care/skincare/au/compare/sesderma-vs-taro - Singapore: https://lovi.care/skincare/sg/compare/sesderma-vs-taro - Saudi Arabia: https://lovi.care/skincare/sa/compare/sesderma-vs-taro - United Arab Emirates: https://lovi.care/skincare/ae/compare/sesderma-vs-taro