# Mesoestetic vs Biluma

Page: https://lovi.care/skincare/uk/compare/mesoestetic-vs-biluma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Mesoestetic and Biluma are specialized skincare lines originating from Spain and India, respectively, designed to elevate daily routines with sophisticated [serums](https://lovi.care/skincare/uk/ingredients/serum) and carefully crafted formulas. The Spanish brand suits mature, sensitive, and uneven skin best, while the Indian brand is ideal for combination, sensitive, and dry skin types. For acne-prone concerns, the former relies on the Cosmelan 2 for stubborn blemishes, whereas the latter features a targeted cream. While both deliver reliable daily care and balanced nourishment through gentle yet rigorous composition, they differ primarily in their specific regional origins, parent companies, and tailored ingredient profiles.

Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L..

[mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk)

Biluma is an Indian skincare brand founded in 2014 and owned by Galderma Group AG.

[galderma.com](https://www.galderma.com/sites/default/files/2026-03/galderma_ar_2025_consolidated-doc_8b_260304_-_full.pdf)

This page compares some of the most popular Mesoestetic and Biluma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgd287eeaa74).

### Popular Mesoestetic vs Biluma products

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/uk/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### Biluma

- [Cream](https://lovi.care/skincare/uk/p/biluma/cream/for/combination-skin) — Average fit

### Mesoestetic vs Biluma [serums](https://lovi.care/skincare/uk/ingredients/serum) and treatments

#### Mesoestetic

- [Cosmelan 2](https://lovi.care/skincare/uk/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit

#### Biluma

- [Cream](https://lovi.care/skincare/uk/p/biluma/cream/for/combination-skin) — Average fit

## Questions and answers

### Mesoestetic or Biluma: which is better?

Both Mesoestetic and Biluma are a match for most skin types on this page, with Lovi giving them an average fit across oily, combination, mature, and acne-prone skin. Neither brand is well-suited for dry or sensitive skin, and all products on this page list no fragrance in their ingredients.

### What is the difference between Mesoestetic and Biluma?

Mesoestetic is a Spanish brand founded in 1984, while Biluma is a newer Indian brand founded in 2014 by Galderma Group AG. Both brands feature fragrance-free products on this page with similar average Lovi fit levels for combination, oily, and acne-prone skin types.

### Which is more affordable, Mesoestetic or Biluma?

Neither Mesoestetic nor Biluma is shown as more affordable, as price information is not available on this page.

### Which causes fewer breakouts, Mesoestetic or Biluma?

Both Mesoestetic and Biluma have an Average Lovi fit for acne-prone skin with the products on this page.

### Which brand is older and where were they founded, Mesoestetic or Biluma?

Mesoestetic is the older brand, having been founded in Spain in 1984, whereas Biluma was founded in India in 2014.

### Do any of the products from Mesoestetic or Biluma contain fragrance?

Every product on this page from Mesoestetic and Biluma lists no fragrance in its ingredients.

### Which company owns Biluma, and when was it founded?

Biluma is owned by Galderma Group AG and was founded in 2014.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations](https://pubmed.ncbi.nlm.nih.gov/26119285/) Arbutin · Journal of Cosmetic Dermatology, 2015
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies](https://pubmed.ncbi.nlm.nih.gov/37681127/) Alpha arbutin · Heliyon, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025

## The brands

- Spanish skincare: [Mesoestetic](https://lovi.care/skincare/uk/brands/mesoestetic)
- Indian skincare: [Biluma](https://lovi.care/skincare/uk/brands/biluma)

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- [The Ordinary vs Mesoestetic](https://lovi.care/skincare/uk/compare/the-ordinary-vs-mesoestetic)
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- [CeraVe vs Mesoestetic](https://lovi.care/skincare/uk/compare/cerave-vs-mesoestetic)
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- [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-mesoestetic)
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- [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/uk/compare/dr-althea-vs-mesoestetic)
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- [Some By Mi vs Mesoestetic](https://lovi.care/skincare/uk/compare/some-by-mi-vs-mesoestetic)
- [Some By Mi vs Biluma](https://lovi.care/skincare/uk/compare/some-by-mi-vs-biluma)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/mesoestetic-vs-biluma
- United Kingdom: https://lovi.care/skincare/uk/compare/mesoestetic-vs-biluma (this page)
- Ireland: https://lovi.care/skincare/ie/compare/mesoestetic-vs-biluma
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- Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-biluma
- Canada: https://lovi.care/skincare/ca/compare/mesoestetic-vs-biluma
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