# Medik8 vs Jole

Page: https://lovi.care/skincare/uk/compare/medik8-vs-jole

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Medik8 and Jole are sophisticated skincare options that offer distinct approaches to daily routines. The British brand features a broad selection of [serums](https://lovi.care/skincare/uk/ingredients/serum), moisturizers, eye products, and toners built around [hyaluronic acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid), while the other brand focuses exclusively on serums. Medik8 suits dry and dry sensitive skin best, with specialized items for acne-prone, dark spot, and mature skin concerns, whereas the alternative option highlights targeted care for acne-prone skin through its key formulation.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Medik8 and Jole products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg3b571789ca).

### Popular Medik8 vs Jole products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [£51.15 at Amazon](https://www.amazon.co.uk/dp/B0DDY3D3QW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/uk/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [£50.00 at Amazon](https://www.amazon.co.uk/dp/B07Y5P314G?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/uk/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [£45.00 at Amazon](https://www.amazon.co.uk/dp/B07GFS6WXH?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/uk/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [£55.00 at Amazon](https://www.amazon.co.uk/dp/B0DP31336Z?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/uk/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [£42.00 at Amazon](https://www.amazon.co.uk/dp/B0C823PSTK?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/uk/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [£65.00 at Amazon](https://www.amazon.co.uk/dp/B093R4NDJS?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/uk/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [£50.00 at Amazon](https://www.amazon.co.uk/dp/B0CVBM45QZ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/uk/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [£60.00 at Amazon](https://www.amazon.co.uk/dp/B00JKSW24A?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

#### Jole

- [Azelaic Acid 10% Serum](https://lovi.care/skincare/uk/p/jole/azelaic-acid-10-serum/for/combination-skin) — High fit

### Medik8 vs Jole [serums](https://lovi.care/skincare/uk/ingredients/serum) and treatments

#### Jole

- [Azelaic Acid 10% Serum](https://lovi.care/skincare/uk/p/jole/azelaic-acid-10-serum/for/combination-skin) — High fit

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [£51.15 at Amazon](https://www.amazon.co.uk/dp/B0DDY3D3QW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/uk/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [£50.00 at Amazon](https://www.amazon.co.uk/dp/B07Y5P314G?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/uk/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [£45.00 at Amazon](https://www.amazon.co.uk/dp/B07GFS6WXH?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/uk/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [£55.00 at Amazon](https://www.amazon.co.uk/dp/B0DP31336Z?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/uk/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [£65.00 at Amazon](https://www.amazon.co.uk/dp/B093R4NDJS?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Super C Ferulic](https://lovi.care/skincare/uk/p/medik8/super-c-ferulic/for/acne-prone-skin) — High fit — [£69.00 at Amazon](https://www.amazon.co.uk/dp/B07DVYFWMD?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Sleep Glycolic](https://lovi.care/skincare/uk/p/medik8/sleep-glycolic/for/oily-acne-prone-skin) — Average fit

## Questions and answers

### What is the difference between Medik8 and Jole?

Medik8 offers a much wider range of twelve products covering cleansers, toners, [serums](https://lovi.care/skincare/uk/ingredients/serum), and moisturizers with various Lovi fit levels, whereas Jole features just a single [azelaic acid](https://lovi.care/skincare/uk/ingredients/azelaic-acid) serum on this page. Medik8 products often highlight key ingredients like [hyaluronic acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid), which helps provide deep hydration and plumping for the skin.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Medik8 or Jole?

Jole offers a single targeted product, while reviewers frequently mention that the products on this page from Medik8 have a high price point.

### Which causes fewer breakouts, Medik8 or Jole?

Medik8 offers products on this page like Surface Radiance Cleanse that achieve a Superior Lovi fit level for acne-prone skin, while Jole features a single azelaic acid serum with a High fit.

### Which Medik8 products have a Superior fit level for dry skin?

On this page, Medik8 offers a few options with a Superior fit level for dry skin, including [Bakuchiol](https://lovi.care/skincare/uk/ingredients/bakuchiol) Peptides, Hydr8 B5 Intense, and Press & Glow.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### How many Medik8 products contain fragrance compared to Jole products?

Medik8 has 11 out of 12 products on this page with no fragrance and only Total Moisture Daily Facial Cream listing fragrance, while every Jole product on this page lists no fragrance.

### What are the common criticisms of Medik8 according to reviewers?

According to reviewers, the products on this page by Medik8 commonly face criticism for their high price point. Shoppers also sometimes note packaging issues as well as slow or delayed results.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024

## The brands

- British skincare: [Medik8](https://lovi.care/skincare/uk/brands/medik8)
- Skincare: [Jole](https://lovi.care/skincare/uk/brands/jole)

## More comparisons

- [SKIN1004 vs Medik8](https://lovi.care/skincare/uk/compare/skin1004-vs-medik8)
- [SKIN1004 vs Jole](https://lovi.care/skincare/uk/compare/skin1004-vs-jole)
- [Anua vs Medik8](https://lovi.care/skincare/uk/compare/anua-vs-medik8)
- [Anua vs Jole](https://lovi.care/skincare/uk/compare/anua-vs-jole)
- [Medicube vs Medik8](https://lovi.care/skincare/uk/compare/medicube-vs-medik8)
- [Medicube vs Jole](https://lovi.care/skincare/uk/compare/medicube-vs-jole)
- [The Ordinary vs Medik8](https://lovi.care/skincare/uk/compare/the-ordinary-vs-medik8)
- [The Ordinary vs Jole](https://lovi.care/skincare/uk/compare/the-ordinary-vs-jole)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-medik8)
- [Beauty of Joseon vs Jole](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-jole)
- [COSRX vs Medik8](https://lovi.care/skincare/uk/compare/cosrx-vs-medik8)
- [COSRX vs Jole](https://lovi.care/skincare/uk/compare/cosrx-vs-jole)
- [CeraVe vs Medik8](https://lovi.care/skincare/uk/compare/cerave-vs-medik8)
- [CeraVe vs Jole](https://lovi.care/skincare/uk/compare/cerave-vs-jole)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-medik8)
- [La Roche-Posay vs Jole](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-jole)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/uk/compare/dr-althea-vs-medik8)
- [Dr. Althea vs Jole](https://lovi.care/skincare/uk/compare/dr-althea-vs-jole)
- [Some By Mi vs Medik8](https://lovi.care/skincare/uk/compare/some-by-mi-vs-medik8)
- [Some By Mi vs Jole](https://lovi.care/skincare/uk/compare/some-by-mi-vs-jole)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medik8-vs-jole
- United Kingdom: https://lovi.care/skincare/uk/compare/medik8-vs-jole (this page)
- Ireland: https://lovi.care/skincare/ie/compare/medik8-vs-jole
- Germany: https://lovi.care/skincare/de/compare/medik8-vs-jole
- France: https://lovi.care/skincare/fr/compare/medik8-vs-jole
- Italy: https://lovi.care/skincare/it/compare/medik8-vs-jole
- Netherlands: https://lovi.care/skincare/nl/compare/medik8-vs-jole
- Spain: https://lovi.care/skincare/es/compare/medik8-vs-jole
- Canada: https://lovi.care/skincare/ca/compare/medik8-vs-jole
- Australia: https://lovi.care/skincare/au/compare/medik8-vs-jole
- Singapore: https://lovi.care/skincare/sg/compare/medik8-vs-jole
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medik8-vs-jole
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medik8-vs-jole