# Medik8 vs ISDIN

Page: https://lovi.care/skincare/uk/compare/medik8-vs-isdin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Medik8 and ISDIN are established skincare brands from the United Kingdom and Spain that offer diverse formulations for daily care. The British brand is known for [serums](https://lovi.care/skincare/uk/ingredients/serum), moisturizers, eye products, and toners built around [hyaluronic acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid), while the Spanish counterpart is beloved for sophisticated moisturizers, advanced sunscreens, targeted serums, and soothing eye products driven by meticulously crafted formulas. Both brands suit dry skin and sensitive skin best, though the former fits dry sensitive skin particularly well. They differ in their standout targeted solutions, specific key ingredients, and individual founding years.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular Medik8 and ISDIN products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg3c2faa50d8).

### Popular Medik8 vs ISDIN products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/uk/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [£51.15 at Amazon](https://www.amazon.co.uk/dp/B0DDY3D3QW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/uk/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [£50.00 at Amazon](https://www.amazon.co.uk/dp/B07Y5P314G?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/uk/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [£45.00 at Amazon](https://www.amazon.co.uk/dp/B07GFS6WXH?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/uk/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [£55.00 at Amazon](https://www.amazon.co.uk/dp/B0DP31336Z?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/uk/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [£42.00 at Amazon](https://www.amazon.co.uk/dp/B0C823PSTK?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/uk/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [£65.00 at Amazon](https://www.amazon.co.uk/dp/B093R4NDJS?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/uk/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [£50.00 at Amazon](https://www.amazon.co.uk/dp/B0CVBM45QZ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/uk/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [£60.00 at Amazon](https://www.amazon.co.uk/dp/B00JKSW24A?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/uk/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [£29.20 at Amazon](https://www.amazon.co.uk/dp/B00D3HXWCK?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/uk/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [£23.49 at Amazon](https://www.amazon.co.uk/dp/B00Z72U6JQ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/uk/p/isdin/k-ox-eyes/for/dry-skin) — High fit
- [Hyaluronic Concentrate](https://lovi.care/skincare/uk/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/uk/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [£38.90 at Amazon](https://www.amazon.co.uk/dp/B01BMLQ086?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/uk/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/uk/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [£71.32 at Amazon](https://www.amazon.co.uk/dp/B0BD9DK6SC?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

## People Say

Medik8

ISDIN

- Lightweight and Elegant Texture Often Mentioned Mostly Mentioned “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “Lightweight formula absorbs fast — ISDIN Hyaluronic Concentrate” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream”
- Deep Hydration and Plumping Often Mentioned Mostly Mentioned “Improved moisture and texture — ISDIN Hyaluronic Moisture” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water” “skin looks smooth and healthy — ISDIN K-Ox Eyes” “Restores moisture — Medik8 Liquid Peptides”
- Gentle and Non-Irritating Formulation Mostly Mentioned Often Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture”
- Brightening, Glow, and Fading Dark Spots Often Mentioned Sometimes Noted “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “pigmentation lightened slightly — Medik8 Oxy-R Peptides” “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- Improves Skin Texture and Smoothness Often Mentioned Rarely Noted “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3” “skin was much smoother — ISDIN Retinal Intense Serum”
- Good Makeup Compatibility Rarely Noted Sometimes Noted “acts like a primer — ISDIN Eryfotona Actinica” “Great under makeup — ISDIN Hyaluronic Concentrate” “layers well under sunscreen — Medik8 Total Moisture Daily Facial Cream”
- High Price Point and Value Often Mentioned Often Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “very expensive — ISDIN Eryfotona Actinica” “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water”
- Slow or Ineffective Results Sometimes Noted Rarely Noted “don't see result — ISDIN K-Ox Eyes” “no noticeable changes yet — ISDIN Retinal Intense Serum” “Not as effective as retinol — Medik8 Bakuchiol Peptides”
- Unpleasant Smell or Strong Fragrance Rarely Noted Often Mentioned “metallic scent — Medik8 Super C Ferulic” “smell is overpowering — ISDIN Eryfotona Actinica”

### Medik8 vs ISDIN routines for dry skin

#### Medik8-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [£8.29 at Amazon](https://www.amazon.co.uk/dp/B07C5R51Q9?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [£11.49 at Amazon](https://www.amazon.co.uk/dp/B07B65NJLV?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/uk/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [£60.00 at Amazon](https://www.amazon.co.uk/dp/B00JKSW24A?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/dry-skin) — Superior fit — [£22.00 at Amazon](https://www.amazon.co.uk/dp/B0C5WCCZ64?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [£13.58 at Amazon](https://www.amazon.co.uk/dp/B084Q16G8D?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/uk/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [£55.00 at Amazon](https://www.amazon.co.uk/dp/B0DP31336Z?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/uk/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0DWXHYJKY?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

#### ISDIN-focused routine

- Cleanser: [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [£8.29 at Amazon](https://www.amazon.co.uk/dp/B07C5R51Q9?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [£11.49 at Amazon](https://www.amazon.co.uk/dp/B07B65NJLV?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — [£14.74 at Amazon](https://www.amazon.co.uk/dp/B0BTPGPK7H?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/uk/p/isdin/fusion-water/for/dry-skin) — Superior fit — [£23.49 at Amazon](https://www.amazon.co.uk/dp/B00Z72U6JQ?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [£13.58 at Amazon](https://www.amazon.co.uk/dp/B084Q16G8D?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/dry-skin) — Average fit — [£38.90 at Amazon](https://www.amazon.co.uk/dp/B01BMLQ086?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/uk/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0DWXHYJKY?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · £187.36 · 97% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B07C5R51Q9&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B0C5WCCZ64&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0DP31336Z&Quantity.6=1&ASIN.7=B0DWXHYJKY&Quantity.7=1&AssociateTag=lovi-care-web-routine-21) [Buy ISDIN routine · £127.49 · 94% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B07C5R51Q9&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B0BTPGPK7H&Quantity.3=1&ASIN.4=B00Z72U6JQ&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B01BMLQ086&Quantity.6=1&ASIN.7=B0DWXHYJKY&Quantity.7=1&AssociateTag=lovi-care-web-routine-21) [See multi-brand routine · 99% fit](https://lovi.care/skincare/uk/skin/dry-skin)

### Medik8 vs ISDIN routines for oily skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [£8.29 at Amazon](https://www.amazon.co.uk/dp/B07C5SKVL7?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [£13.98 at Amazon](https://www.amazon.co.uk/dp/B08125WDCF?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — [£14.80 at Amazon](https://www.amazon.co.uk/dp/B01CLTKI4A?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/uk/p/isdin/eryfotona-actinica/for/oily-skin) — High fit — [£29.20 at Amazon](https://www.amazon.co.uk/dp/B00D3HXWCK?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/uk/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0DNJMQFHK?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/uk/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [£29.00 at Amazon](https://www.amazon.co.uk/dp/B0FJ8Y4MTL?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/oily-skin) — High fit — [£38.90 at Amazon](https://www.amazon.co.uk/dp/B01BMLQ086?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Dr. Sebagh Deep Exfoliating Mask](https://lovi.care/skincare/uk/p/dr-sebagh/deep-exfoliating-mask/for/oily-skin) — Superior fit — [£61.99 at Amazon](https://www.amazon.co.uk/dp/B003E71NPC?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/uk/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [£8.29 at Amazon](https://www.amazon.co.uk/dp/B07C5SKVL7?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [£13.98 at Amazon](https://www.amazon.co.uk/dp/B08125WDCF?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/uk/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [£60.00 at Amazon](https://www.amazon.co.uk/dp/B00JKSW24A?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/uk/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [£11.29 at Amazon](https://www.amazon.co.uk/dp/B0BT6VDJ5M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/uk/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0DNJMQFHK?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/uk/p/medik8/press-and-glow/for/oily-skin) — Average fit — [£29.00 at Amazon](https://www.amazon.co.uk/dp/B093RPJY32?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/uk/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [£65.00 at Amazon](https://www.amazon.co.uk/dp/B093R4NDJS?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Dr. Sebagh Deep Exfoliating Mask](https://lovi.care/skincare/uk/p/dr-sebagh/deep-exfoliating-mask/for/oily-skin) — Superior fit — [£61.99 at Amazon](https://www.amazon.co.uk/dp/B003E71NPC?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · £232.16 · 93% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B00D3HXWCK&Quantity.4=1&ASIN.5=B0DNJMQFHK&Quantity.5=1&ASIN.6=B0FJ8Y4MTL&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B0FNWV4X1F&Quantity.8=1&ASIN.9=B003E71NPC&Quantity.9=1&AssociateTag=lovi-care-web-routine-21) [Buy Medik8 routine · £285.55 · 89% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B0BT6VDJ5M&Quantity.4=1&ASIN.5=B0DNJMQFHK&Quantity.5=1&ASIN.6=B093RPJY32&Quantity.6=1&ASIN.7=B093R4NDJS&Quantity.7=1&ASIN.8=B0FNWV4X1F&Quantity.8=1&ASIN.9=B003E71NPC&Quantity.9=1&AssociateTag=lovi-care-web-routine-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/uk/skin/oily-skin)

### Medik8 vs ISDIN routines for combination skin

#### ISDIN-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [£14.99 at Amazon](https://www.amazon.co.uk/dp/B0013522FC?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [£30.37 at Amazon](https://www.amazon.co.uk/dp/B07P7VZ2J9?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/uk/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — [£14.80 at Amazon](https://www.amazon.co.uk/dp/B01CLTKI4A?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/uk/p/isdin/eryfotona-actinica/for/combination-skin) — High fit — [£29.20 at Amazon](https://www.amazon.co.uk/dp/B00D3HXWCK?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/uk/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [£23.92 at Amazon](https://www.amazon.co.uk/dp/B08QTT1QBX?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [REN Clean Skincare Ready Steady Glow Daily AHA Tonic](https://lovi.care/skincare/uk/p/ren-clean-skincare/ready-steady-glow-daily-aha-tonic/for/combination-skin) — Superior fit — [£30.99 at Amazon](https://www.amazon.co.uk/dp/B07BDKDWCB?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/combination-skin) — High fit — [£38.90 at Amazon](https://www.amazon.co.uk/dp/B01BMLQ086?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/uk/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0DHGWK3FT?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medik8-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/uk/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [£14.99 at Amazon](https://www.amazon.co.uk/dp/B0013522FC?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [£30.37 at Amazon](https://www.amazon.co.uk/dp/B07P7VZ2J9?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/uk/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [£60.00 at Amazon](https://www.amazon.co.uk/dp/B00JKSW24A?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/uk/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [£23.92 at Amazon](https://www.amazon.co.uk/dp/B08QTT1QBX?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/uk/p/medik8/press-and-glow/for/combination-skin) — High fit — [£29.00 at Amazon](https://www.amazon.co.uk/dp/B093RPJY32?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/uk/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [£65.00 at Amazon](https://www.amazon.co.uk/dp/B093R4NDJS?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/uk/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0DHGWK3FT?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · £221.17 · 93% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B0013522FC&Quantity.1=1&ASIN.2=B07P7VZ2J9&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B00D3HXWCK&Quantity.4=1&ASIN.5=B08QTT1QBX&Quantity.5=1&ASIN.6=B07BDKDWCB&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B0FNWV4X1F&Quantity.8=1&ASIN.9=B0DHGWK3FT&Quantity.9=1&AssociateTag=lovi-care-web-routine-21) [Buy Medik8 routine · £261.28 · 92% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B0013522FC&Quantity.1=1&ASIN.2=B07P7VZ2J9&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B08QTT1QBX&Quantity.4=1&ASIN.5=B093RPJY32&Quantity.5=1&ASIN.6=B093R4NDJS&Quantity.6=1&ASIN.7=B0FNWV4X1F&Quantity.7=1&ASIN.8=B0DHGWK3FT&Quantity.8=1&AssociateTag=lovi-care-web-routine-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/uk/skin/combination-skin)

## Questions and answers

### Medik8 or ISDIN: which is better?

Both brands are great choices depending on your skin goals, as ISDIN reaches a superior routine fit for oily skin and acne-prone skin, while Medik8 excels in gentle formulations and brightening. For deep hydration and plumping, the products on this page help improve skin quality with ingredients like [hyaluronic acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid).

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Medik8 and ISDIN?

Medik8 stands out for its gentle, non-irritating [serums](https://lovi.care/skincare/uk/ingredients/serum) and its focus on brightening and improving skin texture, whereas ISDIN is best known for its ultralight, highly compatible sunscreens and lightweight moisturizers. Both brands share a high price point, but Medik8 products on this page generally avoid added fragrance while several ISDIN formulas include it.

### Medik8 or ISDIN for dry skin?

Both Medik8 and ISDIN are great choices for dry skin, earning a Superior routine fit on this page. ISDIN stands out for its ultralight sunscreens and lightweight moisturizers, while Medik8 is known for gentle, hydrating formulas with hyaluronic acid that help improve skin texture.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or ISDIN: which moisturizer is better?

Medik8 stands out for its deep hydration and gentle, fragrance-conscious approach, while ISDIN offers exceptionally lightweight moisturizers with ultralight finishes. Lovi rates Medik8 as High for dry skin and sensitive skin, and ISDIN as Average for those same types. Topical hyaluronic acid, a key ingredient featured in these formulations, helps provide deep hydration and improve skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Medik8 or ISDIN?

Both Medik8 and ISDIN share a high price point as a common drawback noted by reviewers, meaning neither brand is notably more affordable than the other.

### Between Medik8 and ISDIN, which brand is better for reducing dark spots and brightening the skin?

Medik8 does better for brightening, glow, and fading dark spots among the products on this page.

### Which brand has more fragrance-free products, Medik8 or ISDIN?

Medik8 has more fragrance-free products on this page, with eleven out of twelve products listing no fragrance compared to three out of eight for ISDIN.

### Medik8 or ISDIN: which is better for improving skin texture and smoothness?

Medik8 is better for improving skin texture and smoothness.

### Medik8 or ISDIN for oily skin?

For oily skin, ISDIN reaches a Superior routine fit, while Medik8 reaches a High fit. Reviewers mostly mention ISDIN for ultralight and lightweight sunscreens and moisturizers.

### Medik8 or ISDIN for sensitive skin?

Both Medik8 and ISDIN have a Superior Lovi fit for sensitive skin, but Medik8 is often noted for its especially gentle and non-irritating formulations. Topical hyaluronic acid, a key ingredient in products on this page, helps improve skin quality and hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or ISDIN for acne-prone skin?

For acne-prone skin, Lovi rates ISDIN as Superior and Medik8 as High. The products on this page help improve hydration and skin appearance with key ingredients like hyaluronic acid.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
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## The brands

- British skincare: [Medik8](https://lovi.care/skincare/uk/brands/medik8)
- Spanish skincare: [ISDIN](https://lovi.care/skincare/uk/brands/isdin)

## More comparisons

- [SKIN1004 vs Medik8](https://lovi.care/skincare/uk/compare/skin1004-vs-medik8)
- [SKIN1004 vs ISDIN](https://lovi.care/skincare/uk/compare/skin1004-vs-isdin)
- [Anua vs Medik8](https://lovi.care/skincare/uk/compare/anua-vs-medik8)
- [Anua vs ISDIN](https://lovi.care/skincare/uk/compare/anua-vs-isdin)
- [Medicube vs Medik8](https://lovi.care/skincare/uk/compare/medicube-vs-medik8)
- [Medicube vs ISDIN](https://lovi.care/skincare/uk/compare/medicube-vs-isdin)
- [The Ordinary vs Medik8](https://lovi.care/skincare/uk/compare/the-ordinary-vs-medik8)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/uk/compare/the-ordinary-vs-isdin)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-medik8)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-isdin)
- [COSRX vs Medik8](https://lovi.care/skincare/uk/compare/cosrx-vs-medik8)
- [COSRX vs ISDIN](https://lovi.care/skincare/uk/compare/cosrx-vs-isdin)
- [CeraVe vs Medik8](https://lovi.care/skincare/uk/compare/cerave-vs-medik8)
- [CeraVe vs ISDIN](https://lovi.care/skincare/uk/compare/cerave-vs-isdin)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-medik8)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-isdin)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/uk/compare/dr-althea-vs-medik8)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/uk/compare/dr-althea-vs-isdin)
- [Some By Mi vs Medik8](https://lovi.care/skincare/uk/compare/some-by-mi-vs-medik8)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/uk/compare/some-by-mi-vs-isdin)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medik8-vs-isdin
- United Kingdom: https://lovi.care/skincare/uk/compare/medik8-vs-isdin (this page)
- Ireland: https://lovi.care/skincare/ie/compare/medik8-vs-isdin
- Germany: https://lovi.care/skincare/de/compare/medik8-vs-isdin
- France: https://lovi.care/skincare/fr/compare/medik8-vs-isdin
- Italy: https://lovi.care/skincare/it/compare/medik8-vs-isdin
- Netherlands: https://lovi.care/skincare/nl/compare/medik8-vs-isdin
- Spain: https://lovi.care/skincare/es/compare/medik8-vs-isdin
- Canada: https://lovi.care/skincare/ca/compare/medik8-vs-isdin
- Australia: https://lovi.care/skincare/au/compare/medik8-vs-isdin
- Singapore: https://lovi.care/skincare/sg/compare/medik8-vs-isdin
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medik8-vs-isdin
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medik8-vs-isdin