# Medicube vs Simple

Page: https://lovi.care/skincare/uk/compare/medicube-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Medicube and Simple represent two distinct skincare traditions, with the former being a South Korean innovator established in 2016 and the latter a British heritage line originating in 1960. The Korean brand is celebrated for nourishing moisturizers, [serums](https://lovi.care/skincare/uk/ingredients/serum), toners, and masks featuring [niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide), [collagen](https://lovi.care/skincare/uk/ingredients/collagen), and [hyaluronic acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid) to support dry and oily acne-prone skin. Conversely, the British line is cherished for gentle cleansers, makeup removers, moisturizers, and toners utilizing niacinamide and [glycerin](https://lovi.care/skincare/uk/ingredients/glycerin) to comfort acne-prone skin and skin with dark spots. Ultimately, they differ through their specialized offerings, as the former targets advanced elasticity and clarity while the latter emphasizes fundamental barrier health.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular Medicube and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg07f4e790a7).

### Popular Medicube vs Simple products

#### Medicube

- [Zero Pore Pad](https://lovi.care/skincare/uk/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [£15.30 at Amazon](https://www.amazon.co.uk/dp/B0CV7RX6ML?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Peptide Serum](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [£13.80 at Amazon](https://www.amazon.co.uk/dp/B0G29RKZ1H?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Collagen Jelly Cream](https://lovi.care/skincare/uk/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [£14.80 at Amazon](https://www.amazon.co.uk/dp/B0CM2PPNMW?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Collagen Night Wrapping Mask](https://lovi.care/skincare/uk/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit — [£17.90 at Lookfantastic](https://www.lookfantastic.com/p/medicube-collagen-night-wrapping-mask-75ml/16858530/)
- [PDRN Pink Collagen Gel Mask](https://lovi.care/skincare/uk/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin) — High fit — [£4.70 at Amazon](https://www.amazon.co.uk/dp/B0DBF52CLJ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [DEEP VITA-C CAPSULE CREAM](https://lovi.care/skincare/uk/p/medicube/deep-vita-c-capsule-cream/for/sensitive-skin) — Average fit — [£15.51 at Amazon](https://www.amazon.co.uk/dp/B0D2Z3GGCY?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [TRIPLE COLLAGEN CREAM](https://lovi.care/skincare/uk/p/medicube/triple-collagen-cream/for/mature-skin) — Average fit — [£25.83 at Amazon](https://www.amazon.co.uk/dp/B0FH6WTB14?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Zero Foam Cleanser](https://lovi.care/skincare/uk/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [£12.90 at Amazon](https://www.amazon.co.uk/dp/B09C1B7BH5?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

#### Simple

- [Micellar Water](https://lovi.care/skincare/uk/p/simple/micellar-water/for/mature-skin) — Average fit — [£19.49 at Amazon](https://www.amazon.co.uk/dp/B0DYZ8JHBQ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/uk/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [£19.48 at Amazon](https://www.amazon.co.uk/dp/B0DYZ8JHBQ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/uk/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [£2.56 at Amazon](https://www.amazon.co.uk/dp/B000LQX6XG?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/uk/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [£4.28 at Amazon](https://www.amazon.co.uk/dp/B00H1TUFAI?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/uk/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [£2.74 at Amazon](https://www.amazon.co.uk/dp/B014G4ZW1M?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/uk/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [£9.50 at Amazon](https://www.amazon.co.uk/dp/B0D1VFWTJ9?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/uk/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [£1.90 at Amazon](https://www.amazon.co.uk/dp/B076V2D94Y?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

## People Say

Medicube

Simple

- Soothing and Gentle Formulas Often Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “refreshing sensation — Medicube PDRN Pink Collagen Gel Mask”
- Hydration and Moisture Mostly Mentioned Mostly Mentioned “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum” “glass skin — Medicube PDRN Pink Collagen Gel Mask” “banished dryness within days — Simple Replenishing Rich Moisturiser” “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water”
- Affordable Value Not noted Often Mentioned “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water”
- Packaging and Conveniences Often Mentioned Rarely Noted “tweezers included are hygienic — Medicube Zero Pore Pad” “perfect slip for my device — Medicube Collagen Jelly Cream” “keeps my skincare in place — Medicube Collagen Night Wrapping Mask” “No need to rinse... perfect for traveling or lazy nights. — Simple Micellar Cleansing Water”
- Lightweight and Non-Greasy Not noted Often Mentioned “sinks in instantly — Simple Water Boost Hydrating Gel Cream” “absorbs very quickly — Simple Hydrating Light Moisturiser” “absorbs really well — Simple Replenishing Rich Moisturiser”
- Glow and Radiance Often Mentioned Not noted “gave me instant glass skin — Medicube Collagen Jelly Cream” “woke up with glowing skin — Medicube Collagen Night Wrapping Mask” “Dark spots go away faster — Medicube Deep Vita C Pad”
- Sticky or Heavy Residue Often Mentioned Sometimes Noted “Feels slimy on skin — Simple Refreshing Facial Wash” “Still feeling a little bit of a film on my skin. — Simple Micellar Cleansing Water” “leaves a tacky film — Simple Kind to Skin Soothing Facial Toner” “hair sticks to my face — Medicube Collagen Jelly Cream”
- Breakouts and Skin Irritation Often Mentioned Sometimes Noted “caused redness and sensitivity — Medicube Zero Pore Pad” “woke up with whiteheads — Medicube Collagen Night Wrapping Mask” “Gave me tiny bumps on my forehead. — Simple Micellar Water” “caused major breakouts — Simple Hydrating Light Moisturiser”
- Drying and Stripping Effects Sometimes Noted Sometimes Noted “Skin feels very tight — Medicube Zero Foam Cleanser” “skin felt very tight — Medicube Zero Pore Blackhead Mud Mask” “not moisturizing enough — Simple Hydrating Light Moisturiser” “skin felt tight after an hour — Simple Water Boost Hydrating Gel Cream”

### Medicube vs Simple routines for dry skin

#### Medicube-focused routine

- Cleanser: [Zero Foam Cleanser](https://lovi.care/skincare/uk/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [£12.90 at Amazon](https://www.amazon.co.uk/dp/B09C1B7BH5?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/uk/p/medicube/triple-collagen-toner/for/dry-skin) — High fit — [£14.20 at Amazon](https://www.amazon.co.uk/dp/B085VS2J3T?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/uk/p/medicube/age-r-booster-gel/for/dry-skin) — Superior fit — [£13.11 at Amazon](https://www.amazon.co.uk/dp/B0DNPWYZMT?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/dry-skin) — Superior fit — [£22.00 at Amazon](https://www.amazon.co.uk/dp/B0C5WCCZ64?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/uk/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [£13.58 at Amazon](https://www.amazon.co.uk/dp/B084Q16G8D?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [One Day Exosome Shot 2000](https://lovi.care/skincare/uk/p/medicube/one-day-exosome-shot-2000/for/dry-skin) — High fit — [£11.99 at Amazon](https://www.amazon.co.uk/dp/B0D16L5F2M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Deep Peptide Radiance Mask](https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/dry-skin) — High fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0HGBQSTDY?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/uk/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [£4.28 at Amazon](https://www.amazon.co.uk/dp/B00H1TUFAI?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/uk/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [£11.49 at Amazon](https://www.amazon.co.uk/dp/B07B65NJLV?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/uk/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [£2.74 at Amazon](https://www.amazon.co.uk/dp/B014G4ZW1M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Torriden DIVE-IN Mild Sunscreen](https://lovi.care/skincare/uk/p/torriden/dive-in-mild-sunscreen/for/dry-skin) — Superior fit — [£22.00 at Amazon](https://www.amazon.co.uk/dp/B0C5WCCZ64?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/uk/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [£19.48 at Amazon](https://www.amazon.co.uk/dp/B0DYZ8JHBQ?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [£59.74 at Amazon](https://www.amazon.co.uk/dp/B08H4QPM19?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/uk/p/mediheal/vita-essential-mask/for/dry-skin) — Superior fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0DWXHYJKY?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medicube routine · £104.78 · 91% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B09C1B7BH5&Quantity.1=1&ASIN.2=B085VS2J3T&Quantity.2=1&ASIN.3=B0DNPWYZMT&Quantity.3=1&ASIN.4=B0C5WCCZ64&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0D16L5F2M&Quantity.6=1&ASIN.7=B0HGBQSTDY&Quantity.7=1&AssociateTag=lovi-care-web-routine-21) [Buy Simple routine · £136.73 · 83% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B00H1TUFAI&Quantity.1=1&ASIN.2=B07B65NJLV&Quantity.2=1&ASIN.3=B014G4ZW1M&Quantity.3=1&ASIN.4=B0C5WCCZ64&Quantity.4=1&ASIN.5=B0DYZ8JHBQ&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B0DWXHYJKY&Quantity.7=1&AssociateTag=lovi-care-web-routine-21) [See multi-brand routine · 99% fit](https://lovi.care/skincare/uk/skin/dry-skin)

### Medicube vs Simple routines for oily skin

#### Medicube-focused routine

- Cleanser: [Red Foam Cleanser](https://lovi.care/skincare/uk/p/medicube/red-foam-cleanser/for/oily-skin) — High fit — [£12.90 at Amazon](https://www.amazon.co.uk/dp/B073ZBXSJD?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/uk/p/medicube/triple-collagen-toner/for/oily-skin) — High fit — [£14.20 at Amazon](https://www.amazon.co.uk/dp/B085VS2J3T?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/uk/p/medicube/age-r-booster-gel/for/oily-skin) — High fit — [£13.11 at Amazon](https://www.amazon.co.uk/dp/B0DNPWYZMT?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/uk/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [£11.29 at Amazon](https://www.amazon.co.uk/dp/B0BT6VDJ5M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/uk/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0DNJMQFHK?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/uk/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [£15.30 at Amazon](https://www.amazon.co.uk/dp/B0CV7RX6ML?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/uk/p/medicube/zero-pore-blackhead-mud-mask/for/oily-skin) — Average fit — [£14.00 at Amazon](https://www.amazon.co.uk/dp/B0D1G7XF9X?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/uk/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [£4.28 at Amazon](https://www.amazon.co.uk/dp/B00H1TUFAI?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/uk/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [£13.98 at Amazon](https://www.amazon.co.uk/dp/B08125WDCF?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/uk/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [£2.74 at Amazon](https://www.amazon.co.uk/dp/B014G4ZW1M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/uk/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [£11.29 at Amazon](https://www.amazon.co.uk/dp/B0BT6VDJ5M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/uk/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [£19.48 at Amazon](https://www.amazon.co.uk/dp/B0DYZ8JHBQ?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/uk/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [£29.00 at Amazon](https://www.amazon.co.uk/dp/B0FJ8Y4MTL?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [£59.74 at Amazon](https://www.amazon.co.uk/dp/B08H4QPM19?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Dr. Sebagh Deep Exfoliating Mask](https://lovi.care/skincare/uk/p/dr-sebagh/deep-exfoliating-mask/for/oily-skin) — Superior fit — [£61.99 at Amazon](https://www.amazon.co.uk/dp/B003E71NPC?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medicube routine · £116.80 · 88% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B073ZBXSJD&Quantity.1=1&ASIN.2=B085VS2J3T&Quantity.2=1&ASIN.3=B0DNPWYZMT&Quantity.3=1&ASIN.4=B0BT6VDJ5M&Quantity.4=1&ASIN.5=B0DNJMQFHK&Quantity.5=1&ASIN.6=B0CV7RX6ML&Quantity.6=1&ASIN.7=B0FNWV4X1F&Quantity.7=1&ASIN.8=B0D1G7XF9X&Quantity.8=1&AssociateTag=lovi-care-web-routine-21) [Buy Simple routine · £221.50 · 87% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B00H1TUFAI&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B014G4ZW1M&Quantity.3=1&ASIN.4=B0BT6VDJ5M&Quantity.4=1&ASIN.5=B0DYZ8JHBQ&Quantity.5=1&ASIN.6=B0FJ8Y4MTL&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B0FNWV4X1F&Quantity.8=1&ASIN.9=B003E71NPC&Quantity.9=1&AssociateTag=lovi-care-web-routine-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/uk/skin/oily-skin)

### Medicube vs Simple routines for combination skin

#### Medicube-focused routine

- Cleanser: [Red Foam Cleanser](https://lovi.care/skincare/uk/p/medicube/red-foam-cleanser/for/combination-skin) — High fit — [£12.90 at Amazon](https://www.amazon.co.uk/dp/B073ZBXSJD?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/uk/p/medicube/triple-collagen-toner/for/combination-skin) — High fit — [£14.20 at Amazon](https://www.amazon.co.uk/dp/B085VS2J3T?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/uk/p/medicube/age-r-booster-gel/for/combination-skin) — High fit — [£13.11 at Amazon](https://www.amazon.co.uk/dp/B0DNPWYZMT?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Pyunkang Yul Deep Cleansing Oil](https://lovi.care/skincare/uk/p/pyunkang-yul/deep-cleansing-oil/for/combination-skin) — Superior fit — [£23.92 at Amazon](https://www.amazon.co.uk/dp/B08QTT1QBX?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/uk/p/medicube/zero-pore-pad/for/combination-skin) — Superior fit — [£15.30 at Amazon](https://www.amazon.co.uk/dp/B0CV7RX6ML?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/uk/p/medicube/zero-pore-blackhead-mud-mask/for/combination-skin) — Average fit — [£14.00 at Amazon](https://www.amazon.co.uk/dp/B0D1G7XF9X?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/uk/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [£4.28 at Amazon](https://www.amazon.co.uk/dp/B00H1TUFAI?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/uk/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [£30.37 at Amazon](https://www.amazon.co.uk/dp/B07P7VZ2J9?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/uk/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [£2.74 at Amazon](https://www.amazon.co.uk/dp/B014G4ZW1M?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/uk/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [£19.48 at Amazon](https://www.amazon.co.uk/dp/B0DYZ8JHBQ?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [REN Clean Skincare Ready Steady Glow Daily AHA Tonic](https://lovi.care/skincare/uk/p/ren-clean-skincare/ready-steady-glow-daily-aha-tonic/for/combination-skin) — Superior fit — [£30.99 at Amazon](https://www.amazon.co.uk/dp/B07BDKDWCB?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/uk/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [£59.74 at Amazon](https://www.amazon.co.uk/dp/B08H4QPM19?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/uk/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0FNWV4X1F?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/uk/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0DHGWK3FT?tag=lovi-care-web-routine-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medicube routine · £112.43 · 86% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B073ZBXSJD&Quantity.1=1&ASIN.2=B085VS2J3T&Quantity.2=1&ASIN.3=B0DNPWYZMT&Quantity.3=1&ASIN.4=B08QTT1QBX&Quantity.4=1&ASIN.5=B0CV7RX6ML&Quantity.5=1&ASIN.6=B0FNWV4X1F&Quantity.6=1&ASIN.7=B0D1G7XF9X&Quantity.7=1&AssociateTag=lovi-care-web-routine-21) [Buy Simple routine · £185.60 · 85% fit](https://www.amazon.co.uk/gp/aws/cart/add.html?ASIN.1=B00H1TUFAI&Quantity.1=1&ASIN.2=B07P7VZ2J9&Quantity.2=1&ASIN.3=B014G4ZW1M&Quantity.3=1&ASIN.4=B0DYZ8JHBQ&Quantity.4=1&ASIN.5=B07BDKDWCB&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B0FNWV4X1F&Quantity.7=1&ASIN.8=B0DHGWK3FT&Quantity.8=1&AssociateTag=lovi-care-web-routine-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/uk/skin/combination-skin)

## Questions and answers

### Medicube or Simple: which is better?

Medicube is better for glow and radiance and packaging conveniences, while Simple is better for soothing and gentle formulas, affordable value, and lightweight and non-greasy feel. For dry skin routines, Lovi rates Medicube as Superior and Simple as High.

### What is the difference between Medicube and Simple?

Medicube is a South Korean brand founded in 2016 that excels in glow and radiance, while Simple is a British brand founded in 1960 that focuses on soothing, gentle, and budget-friendly formulas. Both brands offer solid routines for various skin types, but Medicube is often noted for deep hydration and packaging conveniences, whereas Simple provides lightweight and non-greasy options with zero fragrance across its page products.

### Medicube or Simple for dry skin?

Medicube is a better fit for dry skin, where Lovi rates its routine as Superior compared to Simple at High. Reviewers note that Medicube products help provide deep hydration and a radiant glow, though some mention a sticky residue.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medicube or Simple: which cleanser is better?

Medicube is a better fit for cleansers on this page, as its Zero Foam Cleanser and Red Foam Cleanser rate High for dry skin, sensitive skin, and oily acne-prone skin, whereas Simple cleansers rate Low for dry and dry sensitive skin.

### Which is more affordable, Medicube or Simple?

Simple is more affordable, offering value-friendly moisturizers and gentle makeup removers. Reviewers often mention pricing issues and small quantities with Medicube.

### Which brand offers better glow and radiance, Medicube or Simple?

Medicube offers better glow and radiance compared to Simple. Reviewers on the page frequently mention a radiant glow as one of the key benefits of using Medicube products.

### Do Medicube products contain fragrance?

Medicube is mostly fragrance-free, as 23 of the 25 products on this page list no fragrance. Only the [Collagen](https://lovi.care/skincare/uk/ingredients/collagen) Jelly Cream and Deep Vita A [Retinol](https://lovi.care/skincare/uk/ingredients/retinol) [Serum](https://lovi.care/skincare/uk/ingredients/serum) include fragrance in their ingredients.

### Which brand has better packaging and conveniences?

Medicube is better for packaging and conveniences, as it outperforms Simple in that specific review theme.

### Medicube or Simple for oily skin?

Both brands offer a high Lovi fit for oily skin. Medicube features a wider variety of targeted serums and cleansers, while Simple is known for gentle and lightweight everyday options.

### Medicube or Simple: which moisturizer is better?

Medicube is a better option for moisturizers if you want deep hydration and a radiant glow, whereas Simple is better for lightweight, budget-friendly formulas. Lovi rates Medicube's routine fit for dry skin as Superior and Simple's as High.

### Medicube or Simple for sensitive skin?

Medicube and Simple both fit sensitive skin at a High level on this page. Simple offers more soothing and gentle formulas, while Medicube provides better glow and radiance.

### Medicube or Simple for acne-prone skin?

Both brands fit acne-prone skin well, with Lovi rating Medicube High and Simple High. Medicube focuses on targeted treatments with key ingredients like [salicylic acid](https://lovi.care/skincare/uk/ingredients/salicylic-acid) and [niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide), while Simple offers gentle, fragrance-free basics.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/37377400/) Exosome cica · Journal of Cosmetic Dermatology, 2023
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivatives · Experimental Dermatology, 2003
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Aha · Journal of Dermatological Science, 2017
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Tea tree oil reduces histamine-induced skin inflammation](https://pubmed.ncbi.nlm.nih.gov/12452873/) Tree · The British Journal of Dermatology, 2002
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica flower extract · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Protective effects of Camellia japonica flower extract against urban air pollutants](https://pubmed.ncbi.nlm.nih.gov/30691451/) Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28341613/) Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen extract · Nutrients, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Vitamin c derivatives · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid, Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract, Madecassoside, Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine](https://pubmed.ncbi.nlm.nih.gov/34284096/) Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Lifting peptide · Journal of the European Academy of Dermatology and Venereology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis flower extract · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract](https://pubmed.ncbi.nlm.nih.gov/33410284/) Camellia japonica flower extract · FEBS Open Bio, 2021
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial](https://pubmed.ncbi.nlm.nih.gov/37726676/) Portulaca oleracea extract · BMC Oral Health, 2023
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed extract · Skin Pharmacology and Physiology, 2007
- [Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract](https://pubmed.ncbi.nlm.nih.gov/35403355/) Grape seed extract · Journal of Cosmetic Dermatology, 2022
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Composition characterization and clinical efficacy study of a salmon egg extract](https://pubmed.ncbi.nlm.nih.gov/23738607/) Salmon egg extract · International Journal of Cosmetic Science, 2013
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations](https://pubmed.ncbi.nlm.nih.gov/31435711/) Ethanolamine · Archives of Toxicology, 2019
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora](https://pubmed.ncbi.nlm.nih.gov/41516097/) Sodium dna, Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025
- [Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy](https://pubmed.ncbi.nlm.nih.gov/40840755/) Sodium dna · International Journal of Biological Macromolecules, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023

## The brands

- Korean skincare: [Medicube](https://lovi.care/skincare/uk/brands/medicube)
- British skincare: [Simple](https://lovi.care/skincare/uk/brands/simple)

## More comparisons

- [SKIN1004 vs Medicube](https://lovi.care/skincare/uk/compare/skin1004-vs-medicube)
- [SKIN1004 vs Simple](https://lovi.care/skincare/uk/compare/skin1004-vs-simple)
- [Anua vs Medicube](https://lovi.care/skincare/uk/compare/anua-vs-medicube)
- [Anua vs Simple](https://lovi.care/skincare/uk/compare/anua-vs-simple)
- [Medicube vs The Ordinary](https://lovi.care/skincare/uk/compare/medicube-vs-the-ordinary)
- [Medicube vs Beauty of Joseon](https://lovi.care/skincare/uk/compare/medicube-vs-beauty-of-joseon)
- [Medicube vs COSRX](https://lovi.care/skincare/uk/compare/medicube-vs-cosrx)
- [Medicube vs CeraVe](https://lovi.care/skincare/uk/compare/medicube-vs-cerave)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/uk/compare/medicube-vs-la-roche-posay)
- [Medicube vs Dr. Althea](https://lovi.care/skincare/uk/compare/medicube-vs-dr-althea)
- [Medicube vs Some By Mi](https://lovi.care/skincare/uk/compare/medicube-vs-some-by-mi)
- [Medicube vs Torriden](https://lovi.care/skincare/uk/compare/medicube-vs-torriden)
- [Medicube vs celimax](https://lovi.care/skincare/uk/compare/medicube-vs-celimax)
- [Medicube vs Purito](https://lovi.care/skincare/uk/compare/medicube-vs-purito)
- [Medicube vs Cetaphil](https://lovi.care/skincare/uk/compare/medicube-vs-cetaphil)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/uk/compare/medicube-vs-paula-s-choice)
- [Medicube vs Neutrogena](https://lovi.care/skincare/uk/compare/medicube-vs-neutrogena)
- [Medicube vs Kiehl's](https://lovi.care/skincare/uk/compare/medicube-vs-kiehl-s)
- [Medicube vs Caudalie](https://lovi.care/skincare/uk/compare/medicube-vs-caudalie)
- [Medicube vs Dermalogica](https://lovi.care/skincare/uk/compare/medicube-vs-dermalogica)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medicube-vs-simple
- United Kingdom: https://lovi.care/skincare/uk/compare/medicube-vs-simple (this page)
- Ireland: https://lovi.care/skincare/ie/compare/medicube-vs-simple
- Germany: https://lovi.care/skincare/de/compare/medicube-vs-simple
- France: https://lovi.care/skincare/fr/compare/medicube-vs-simple
- Italy: https://lovi.care/skincare/it/compare/medicube-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/medicube-vs-simple
- Spain: https://lovi.care/skincare/es/compare/medicube-vs-simple
- Canada: https://lovi.care/skincare/ca/compare/medicube-vs-simple
- Australia: https://lovi.care/skincare/au/compare/medicube-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/medicube-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medicube-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medicube-vs-simple