# ISDIN vs FANCL

Page: https://lovi.care/skincare/uk/compare/isdin-vs-fancl

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

ISDIN and FANCL are respected skincare brands from Spain and Japan that offer gentle, nourishing care for sensitive and dry skin. The Spanish brand is known for its sophisticated moisturizers, advanced sunscreens, targeted [serums](https://lovi.care/skincare/uk/ingredients/serum), and soothing eye products driven by meticulously crafted formulas, while the Japanese counterpart is loved for thoughtful makeup removers and gentle exfoliants crafted from pure, effective formulas. Both lines feature standout solutions for specific needs, such as the former's Fusion [Water](https://lovi.care/skincare/uk/ingredients/water), Eryfotona Actinica, and K-Ox Eyes, alongside the latter's Facial Washing Powder and Mild Cleansing Oil. They differ primarily in their cultural origins and specific product lineups, with the European house emphasizing advanced sun and targeted care and the Asian house focusing on mild cleansing and daily balance.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

FANCL is a Japanese skincare brand founded in 1980 and owned by Kirin Holdings Company, Limited since 2024.

[fancl.jp](https://www.fancl.jp/en/about/outline/index.html) [en.wikipedia.org](https://en.wikipedia.org/wiki/FANCL_Corporation) [pitchbook.com](https://pitchbook.com/profiles/company/40398-22)

This page compares some of the most popular ISDIN and FANCL products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg0cc391e61f).

### Popular ISDIN vs FANCL products

#### FANCL

- [Mild Cleansing Oil](https://lovi.care/skincare/uk/p/fancl/mild-cleansing-oil/for/dry-sensitive-skin) — Superior fit
- [Facial Washing Powder](https://lovi.care/skincare/uk/p/fancl/facial-washing-powder/for/sensitive-skin) — Superior fit — [£22.24 at Amazon](https://www.amazon.co.uk/dp/B01KTJXVI4?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/uk/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [£29.20 at Amazon](https://www.amazon.co.uk/dp/B00D3HXWCK?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/uk/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [£23.49 at Amazon](https://www.amazon.co.uk/dp/B00Z72U6JQ?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/uk/p/isdin/k-ox-eyes/for/dry-skin) — High fit
- [Hyaluronic Concentrate](https://lovi.care/skincare/uk/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/uk/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [£38.90 at Amazon](https://www.amazon.co.uk/dp/B01BMLQ086?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/uk/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/uk/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [£71.32 at Amazon](https://www.amazon.co.uk/dp/B0BD9DK6SC?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### ISDIN or FANCL: which is better?

Neither brand is universally better, as ISDIN fits sensitive, dry, and acne-prone skin best with options like Eryfotona Actinica, while FANCL focuses on gentle cleansing and exfoliating products with zero added fragrance.

### What is the difference between ISDIN and FANCL?

ISDIN offers a broad selection of sunscreens, moisturizers, [serums](https://lovi.care/skincare/uk/ingredients/serum), and eye products, whereas FANCL features just two items on this page, a cleansing oil and an exfoliating powder. Additionally, every FANCL product on this page lists no fragrance, while several ISDIN products contain added fragrance.

### Which is more affordable, ISDIN or FANCL?

The products on this page for ISDIN feature a high price point according to reviewers, while FANCL is not noted for high pricing on this page.

### Which causes fewer breakouts, ISDIN or FANCL?

FANCL products on this page are well suited for acne-prone skin with High or Superior Lovi fit levels across its items, whereas ISDIN products on this page have more varied acne fits that can range down to Caution and Warning levels for certain moisturizers.

### Which brand has been around longer and where were they founded?

ISDIN has been around longer, having been founded in Spain in 1975, whereas FANCL was founded in Japan in 1980.

### Do both ISDIN and FANCL offer fragrance-free products?

Yes, both ISDIN and FANCL offer fragrance-free options, as 3 of 8 ISDIN products and every FANCL product on this page list no fragrance.

### What are the main pros and cons reviewers mention about ISDIN products?

Reviewers mostly mention that ISDIN products offer ultralight, lightweight, makeup-friendly, and skin-friendly sunscreens and moisturizers, but often note a high price point and sometimes point out a strong fragrance.

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/uk/brands/isdin)
- Japanese skincare: [FANCL](https://lovi.care/skincare/uk/brands/fancl)

## More comparisons

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- [SKIN1004 vs FANCL](https://lovi.care/skincare/uk/compare/skin1004-vs-fancl)
- [Anua vs ISDIN](https://lovi.care/skincare/uk/compare/anua-vs-isdin)
- [Anua vs FANCL](https://lovi.care/skincare/uk/compare/anua-vs-fancl)
- [Medicube vs ISDIN](https://lovi.care/skincare/uk/compare/medicube-vs-isdin)
- [Medicube vs FANCL](https://lovi.care/skincare/uk/compare/medicube-vs-fancl)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/uk/compare/the-ordinary-vs-isdin)
- [The Ordinary vs FANCL](https://lovi.care/skincare/uk/compare/the-ordinary-vs-fancl)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-isdin)
- [Beauty of Joseon vs FANCL](https://lovi.care/skincare/uk/compare/beauty-of-joseon-vs-fancl)
- [COSRX vs ISDIN](https://lovi.care/skincare/uk/compare/cosrx-vs-isdin)
- [COSRX vs FANCL](https://lovi.care/skincare/uk/compare/cosrx-vs-fancl)
- [CeraVe vs ISDIN](https://lovi.care/skincare/uk/compare/cerave-vs-isdin)
- [CeraVe vs FANCL](https://lovi.care/skincare/uk/compare/cerave-vs-fancl)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-isdin)
- [La Roche-Posay vs FANCL](https://lovi.care/skincare/uk/compare/la-roche-posay-vs-fancl)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/uk/compare/dr-althea-vs-isdin)
- [Dr. Althea vs FANCL](https://lovi.care/skincare/uk/compare/dr-althea-vs-fancl)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/uk/compare/some-by-mi-vs-isdin)
- [Some By Mi vs FANCL](https://lovi.care/skincare/uk/compare/some-by-mi-vs-fancl)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/isdin-vs-fancl
- United Kingdom: https://lovi.care/skincare/uk/compare/isdin-vs-fancl (this page)
- Ireland: https://lovi.care/skincare/ie/compare/isdin-vs-fancl
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- Spain: https://lovi.care/skincare/es/compare/isdin-vs-fancl
- Canada: https://lovi.care/skincare/ca/compare/isdin-vs-fancl
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