# Anua vs OPTASE

Page: https://lovi.care/skincare/uk/compare/anua-vs-optase

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United Kingdom.

Anua and OPTASE are distinct skincare options featuring targeted formulations for diverse complexions. The Korean brand focuses on moisturizers, toners, [serums](https://lovi.care/skincare/uk/ingredients/serum), and cleansers using [hyaluronic acid](https://lovi.care/skincare/uk/ingredients/hyaluronic-acid), [heartleaf](https://lovi.care/skincare/uk/ingredients/heartleaf), and [niacinamide](https://lovi.care/skincare/uk/ingredients/niacinamide), making its offerings best suited for dry and oily acne-prone skin. Meanwhile, the second brand provides gentle makeup removers and balanced formulas, ensuring its products suit sensitive, dry, and irritated skin best. Ultimately, they differ through Anua specializing in blemish, aging, and hydration concerns with specific serums and toners, whereas OPTASE supports calm and comfortable daily routines through soothing and restorative care.

Anua is a Korean skincare brand founded in 2019 and owned by The Founders Inc..

[prnewswire.com](https://www.prnewswire.com/news-releases/k-beauty-brand-anua-expands-to-1-400-ulta-beauty-stores-nationwide-302377860.html) [kedglobal.com](https://www.kedglobal.com/venture-capital/newsView/ked202508270007) [tracxn.com](https://tracxn.com/d/companies/anua/__ACk-pOjQlSruvr7Y8cEcbxHxoGCJM7IgYiTu-IOyWfA) [v.daum.net](https://v.daum.net/v/20250829150137871)

This page compares some of the most popular Anua and OPTASE products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgda2a183090).

### Popular Anua vs OPTASE products

#### Anua

- [Heartleaf Pore Control Cleansing Oil](https://lovi.care/skincare/uk/p/anua/heartleaf-pore-control-cleansing-oil/for/sensitive-skin) — High fit — [£18.00 at Amazon](https://www.amazon.co.uk/dp/B0CX8X7LVM?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Heartleaf 77% Soothing Toner](https://lovi.care/skincare/uk/p/anua/heartleaf-77-soothing-toner/for/mature-skin) — High fit — [£17.00 at Amazon](https://www.amazon.co.uk/dp/B0CRKW57B8?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Niacinamide 10% + TXA 4% Serum](https://lovi.care/skincare/uk/p/anua/niacinamide-10-txa-4-serum/for/oily-acne-prone-skin) — Superior fit — [£19.79 at Amazon](https://www.amazon.co.uk/dp/B0DL92QM79?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [PDRN Hyaluronic Acid Capsule 100 Serum](https://lovi.care/skincare/uk/p/anua/pdrn-hyaluronic-acid-capsule-100-serum/for/dark-spots) — High fit — [£28.40 at Notino](https://www.notino.co.uk/anua/k-pop-demon-hunters-pdrn-hyaluronic-acid-capsule-100-serum-moisturising-and-nourishing-serum-with-collagen/p-16394713/)
- [Heartleaf Quercetin Pore Deep Cleansing Foam](https://lovi.care/skincare/uk/p/anua/heartleaf-quercetin-pore-deep-cleansing-foam/for/acne-prone-skin) — High fit — [£13.00 at Amazon](https://www.amazon.co.uk/dp/B0DKSVZR69?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Rice 70 Glow Milky Toner](https://lovi.care/skincare/uk/p/anua/rice-70-glow-milky-toner/for/dry-skin) — Superior fit — [£19.00 at Amazon](https://www.amazon.co.uk/dp/B0DKRXGHS7?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [PEACH 70% NIACINAMIDE SERUM](https://lovi.care/skincare/uk/p/anua/peach-70-niacinamide-serum/for/acne-prone-skin) — High fit — [£20.00 at Amazon](https://www.amazon.co.uk/dp/B0DKS82VSC?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)
- [Heartleaf 77% Clear Pad](https://lovi.care/skincare/uk/p/anua/heartleaf-77-clear-pad/for/sensitive-skin) — High fit — [£18.00 at Amazon](https://www.amazon.co.uk/dp/B08JLMRTZS?tag=lovi-care-web-product-21&linkCode=osi&th=1&psc=1)

#### OPTASE

- [LIFE SENSITIVE EYE MAKEUP REMOVER](https://lovi.care/skincare/uk/p/optase/life-sensitive-eye-makeup-remover/for/sensitive-skin) — High fit

## Questions and answers

### Anua or OPTASE: which is better?

Anua offers a much larger selection of skincare products on this page that fit dry, oily, and oily acne-prone skin best, whereas OPTASE features only a single eye makeup remover. Every product listed for both brands contains no fragrance.

### What is the difference between Anua and OPTASE?

Anua offers a wide range of skincare products on this page tailored for dry skin, oily skin, and oily acne-prone skin, while OPTASE features only a single eye makeup remover. Every product across the pages for both brands lists no fragrance in its ingredients.

### Which is more affordable, Anua or OPTASE?

This page does not provide pricing information for either Anua or OPTASE, so affordability cannot be compared here.

### Which causes fewer breakouts, Anua or OPTASE?

Reviewers note that Anua's products on this page sometimes cause breakouts, whereas OPTASE features only a single eye makeup remover with no reported breakout concerns. Anua's wide range includes various cleansers, toners, and [serums](https://lovi.care/skincare/uk/ingredients/serum) where some users experience breakouts, but individual reactions vary across formulations.

### What are the founding years and parent companies of Anua and OPTASE?

Anua was founded in 2019 and is owned by The Founders Inc., while OPTASE was founded in 2016 and is owned by Scope Health Group.

### Which brand offers a greater variety of products for dry skin and acne-prone skin?

Anua offers a greater variety of products for dry skin and acne-prone skin, with multiple cleansers, toners, serums, and moisturizers reaching High or Superior fit levels for those skin types on this page. OPTASE only features a single makeup remover on the page, which has an Average fit for dry skin and acne-prone skin.

### Do either Anua or OPTASE products contain fragrance?

Every product on this page for both Anua and OPTASE lists no fragrance in its ingredients.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/27213821/) Curcuma longa root extract · Phytotherapy Research, 2016
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/17314442/) Melaleuca alternifolia tree extract · Indian Journal of Dermatology, Venereology and Leprology, 2007
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women](https://pubmed.ncbi.nlm.nih.gov/25378941/) Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy](https://pubmed.ncbi.nlm.nih.gov/39458583/) Centella asiatica extract · Pharmaceutics, 2024
- [Photoprotective Effects of a Hyperoside-Enriched Fraction Prepared from Houttuynia cordata Thunb. on Ultraviolet B-Induced Skin Aging in Human Fibroblasts through the MAPK Signaling Pathway](https://pubmed.ncbi.nlm.nih.gov/34961096/) Houttuynia cordata extract · Plants, 2021
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway](https://pubmed.ncbi.nlm.nih.gov/35204104/) Houttuynia cordata extract · Antioxidants, 2022
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ferulic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Injectable thermo-sensitive and wide-crack self-healing hydrogel loaded with antibacterial anti-inflammatory dipotassium glycyrrhizate for full-thickness skin wound repair](https://pubmed.ncbi.nlm.nih.gov/35245682/) Dipotassium glycyrrhizate · Acta Biomaterialia, 2022
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Madecassoside · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [Formulation and evaluation on human skin of a water-in-oil emulsion containing Muscat hamburg black grape seed extract](https://pubmed.ncbi.nlm.nih.gov/25402429/) Grape seed oil · International Journal of Cosmetic Science, 2015
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract, Madecassoside · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract](https://pubmed.ncbi.nlm.nih.gov/32812663/) Rice extract · International Journal of Cosmetic Science, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Encapsulation of alpha arbutin, a depigmenting agent, in nanosized ethosomes: Invitro and invivo human studies](https://pubmed.ncbi.nlm.nih.gov/37681127/) Alpha-arbutin · Heliyon, 2023
- [Nanogel Containing Gamma-Oryzanol-Loaded Nanostructured Lipid Carriers and TiO2/MBBT: A Synergistic Nanotechnological Approach of Potent Natural Antioxidants and Nanosized UV Filters for Skin Protection](https://pubmed.ncbi.nlm.nih.gov/37242453/) Rice extract · Pharmaceuticals, 2023
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid, Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2021
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Development of grape seed extract based formulations by using non-invasive biophysical technique and its impact on skin aging](https://pubmed.ncbi.nlm.nih.gov/34799340/) Grape seed oil · Pakistan Journal of Pharmaceutical Sciences, 2021
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia sinensis leaf extract · Molecules, 2024
- [Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres](https://pubmed.ncbi.nlm.nih.gov/25876142/) Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed oil · Skin Pharmacology and Physiology, 2007
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [A new topical biotechnological phytocomplex for truncal mild-moderate acne restores skin microbiota balance](https://pubmed.ncbi.nlm.nih.gov/39044362/) Succinic acid · Skin Research and Technology, 2024
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Histometric assessment of the age-related skin response to 2-hydroxy-5-octanoyl benzoic acid](https://pubmed.ncbi.nlm.nih.gov/9603669/) Capryloyl salicylic acid · Skin Pharmacology and Applied Skin Physiology, 1998
- [Genotoxicity of micro- and nano-particles of kaolin in human primary dermal keratinocytes and fibroblasts](https://pubmed.ncbi.nlm.nih.gov/32322315/) Kaolin · Genes and Environment, 2020
- [Emulgels powered by coco-glucoside: A stable and effective synbiotics delivery system for skin care](https://pubmed.ncbi.nlm.nih.gov/40845989/) Coco-glucoside · International Journal of Pharmaceutics, 2025
- [Investigating the Effects of a Manuka Honey, Royal Jelly, and Bee Venom-Derived Face Serum on Skin Health and Signs of Aging](https://pubmed.ncbi.nlm.nih.gov/40291268/) Manuka honey · Cureus, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023

## The brands

- Korean skincare: [Anua](https://lovi.care/skincare/uk/brands/anua)
- Skincare: [OPTASE](https://lovi.care/skincare/uk/brands/optase)

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- [SKIN1004 vs OPTASE](https://lovi.care/skincare/uk/compare/skin1004-vs-optase)
- [Anua vs Medicube](https://lovi.care/skincare/uk/compare/anua-vs-medicube)
- [Anua vs The Ordinary](https://lovi.care/skincare/uk/compare/anua-vs-the-ordinary)
- [Anua vs Beauty of Joseon](https://lovi.care/skincare/uk/compare/anua-vs-beauty-of-joseon)
- [Anua vs COSRX](https://lovi.care/skincare/uk/compare/anua-vs-cosrx)
- [Anua vs CeraVe](https://lovi.care/skincare/uk/compare/anua-vs-cerave)
- [Anua vs La Roche-Posay](https://lovi.care/skincare/uk/compare/anua-vs-la-roche-posay)
- [Anua vs Dr. Althea](https://lovi.care/skincare/uk/compare/anua-vs-dr-althea)
- [Anua vs Some By Mi](https://lovi.care/skincare/uk/compare/anua-vs-some-by-mi)
- [Anua vs Torriden](https://lovi.care/skincare/uk/compare/anua-vs-torriden)
- [Anua vs celimax](https://lovi.care/skincare/uk/compare/anua-vs-celimax)
- [Anua vs Purito](https://lovi.care/skincare/uk/compare/anua-vs-purito)
- [Anua vs Cetaphil](https://lovi.care/skincare/uk/compare/anua-vs-cetaphil)
- [Anua vs Paula's Choice](https://lovi.care/skincare/uk/compare/anua-vs-paula-s-choice)
- [Anua vs Neutrogena](https://lovi.care/skincare/uk/compare/anua-vs-neutrogena)
- [Anua vs Kiehl's](https://lovi.care/skincare/uk/compare/anua-vs-kiehl-s)
- [Anua vs Caudalie](https://lovi.care/skincare/uk/compare/anua-vs-caudalie)
- [Anua vs Dermalogica](https://lovi.care/skincare/uk/compare/anua-vs-dermalogica)
- [Anua vs Good Molecules](https://lovi.care/skincare/uk/compare/anua-vs-good-molecules)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/anua-vs-optase
- United Kingdom: https://lovi.care/skincare/uk/compare/anua-vs-optase (this page)
- Ireland: https://lovi.care/skincare/ie/compare/anua-vs-optase
- Germany: https://lovi.care/skincare/de/compare/anua-vs-optase
- France: https://lovi.care/skincare/fr/compare/anua-vs-optase
- Italy: https://lovi.care/skincare/it/compare/anua-vs-optase
- Netherlands: https://lovi.care/skincare/nl/compare/anua-vs-optase
- Spain: https://lovi.care/skincare/es/compare/anua-vs-optase
- Canada: https://lovi.care/skincare/ca/compare/anua-vs-optase
- Australia: https://lovi.care/skincare/au/compare/anua-vs-optase
- Singapore: https://lovi.care/skincare/sg/compare/anua-vs-optase
- Saudi Arabia: https://lovi.care/skincare/sa/compare/anua-vs-optase
- United Arab Emirates: https://lovi.care/skincare/ae/compare/anua-vs-optase