# ZO Skin Health Growth Factor Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [ZO Skin Health](https://lovi.care/skincare/sg/brands/zo-skin-health)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Highly suitable for your oily skin, Panthenyl Triacetate and Ethyl Linoleate help regulate sebum and reduce inflammation, though the formula primarily offers general hydration with Glycerin and Butylene Glycol rather than directly targeting oily shine.
- Buddleja Davidii Meristem Cell Culture and Dipeptide Diaminobutyroyl Benzylamide Diacetate provide moderate skin regeneration and fine line reduction, supporting overall skin health.
- The product is safe for your oily skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Dipeptide Diaminobutyroyl Benzylamide Diacetate, Adenosine Triphosphate, Beta-Glucan, Angelica Polymorpha Sinensis Root Extract, Hydrolyzed Sericin

## What the research says

- A lotion containing triethyl citrate and ethyl linoleate reduced Leeds grading, total, inflammatory, and noninflammatory lesion counts, and sebum production compared with a placebo in patients with mild to moderate acne. ([The British Journal of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17635508/))
- Treatment with a bioactive complex of Panthenyl triacetate and Ethyl linoleate at 3% protected human skin biopsies against UV-induced protein oxidation by 72% with pre-treatment and 78% with post-treatment, while also stimulating the expression of protein repairing enzymes compared to UV-irradiated controls. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/19818086/))
- Bakuchiol and ethyl (linoleate/oleate) synergistically inhibit eCB degradation to favor eCB mobilization and repress inflammatory mediators in keratinocytes. ([JID Innovations, 2023](https://pubmed.ncbi.nlm.nih.gov/36992949/))
- A novel anti-aging serum containing acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate, gluconolactone, niacinamide, and laminaria extract significantly increased anti-aging biomarkers and improved static and dynamic wrinkles as well as skin quality in clinical studies. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41668671/))
- Verbascoside- and teupolioside-containing extracts significantly accelerated wound healing, exhibited anti-inflammatory action, inhibited reactive oxygen species release, and suppressed chemokine and growth factor expression in cultured human keratinocytes compared to pro-inflammatory controls. ([Cellular and Molecular Biology, 2007](https://pubmed.ncbi.nlm.nih.gov/17543237/))
- The application of a vitamin B12 and adenosine triphosphate complex improved skin radiance, elasticity, and texture in human participants. ([Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/39194754/))
- Direct delivery of intracellular adenosine triphosphate using ATP-encapsulated fusogenic small unilamellar lipid vesicles accelerated wound healing, improved granular tissue development, re-epithelialization, and increased vascular endothelial growth factor expression compared to lipid vesicles alone in adult nude mice. ([American Journal of Surgery, 2007](https://pubmed.ncbi.nlm.nih.gov/17236849/))
- A self-powered chloroplast-driven nanophotosystem consisting of Chlorella-derived nanothylakoid units and hyaluronic acid microneedles increased mitochondrial biogenesis, adenosine triphosphate generation, and NAD(P)H pools in senescent fibroblasts, leading to increased collagen synthesis and alleviated skin photoaging. ([Journal of Nanobiotechnology, 2026](https://pubmed.ncbi.nlm.nih.gov/42144642/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Angelica sinensis essential oil at 5%-10% demonstrated significant anti-acne effects comparable to adapalene gel with reduced side effects in mice by suppressing Cutibacterium acnes and downregulating IL-1β. ([Journal of Ethnopharmacology, 2026](https://pubmed.ncbi.nlm.nih.gov/41482092/))
- An Angelica sinensis extract containing 1% ligustilide demonstrated anti-inflammatory, antioxidant, anti-senescence, matrix-supportive, and antimicrobial effects in human keratinocytes and dermal fibroblasts. ([Frontiers in Pharmacology, 2026](https://pubmed.ncbi.nlm.nih.gov/41948733/))
- Topical application of Angelica sinensis extract induced noticeable hair regrowth, restored hair shaft lengths and follicle size, and decreased apoptotic cells in C57BL/6 mice. ([The American Journal of Chinese Medicine, 2014](https://pubmed.ncbi.nlm.nih.gov/25004889/))
- Bacterial cellulose wound dressing containing silk sericin and PHMB improved wound quality and reduced pain compared to Bactigras in patients with split-thickness skin graft donor-site wounds. ([Archives of Dermatological Research, 2018](https://pubmed.ncbi.nlm.nih.gov/30302557/))
- A bacterial nanocellulose wound dressing incorporating polyhexamethylene biguanide and sericin showed no skin irritation in healthy volunteers and significantly promoted wound healing with lower wound size and higher collagen formation in full-thickness rat wounds compared to controls. ([Archives of Dermatological Research, 2016](https://pubmed.ncbi.nlm.nih.gov/26796543/))
- Topical application of sericin gels increased skin intrinsic moisturization, hydroxyproline content, and epidermal hydration while decreasing transepidermal water loss and skin impedance in healthy human volunteers. ([Journal of Cosmetic Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/17168872/))

## Why other serums fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Based on a very large amount of data, this product is highly regarded by users with aging, dry, and sensitive skin for its hydrating and plumping effects, visibly reducing fine lines. The lightweight gel formula is frequently praised for restoring the skin's moisture barrier and improving texture. However, some users with acne-prone skin report breakouts, and the high price is a common concern.

- Liked: Lightweight gel (mostly mentioned)
- Liked: Hydrating, plumping (often mentioned)
- Disliked: Very expensive (often mentioned)
- Liked: Gentle, soothing (sometimes noted)
- Liked: Reduces lines (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Faulty pump (rarely noted)
- Disliked: Pills under makeup (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does ZO Growth Factor Serum work for oily skin?

This serum works reasonably well for oily skin, though other products fit it better. Panthenyl Triacetate and Ethyl Linoleate help regulate sebum and reduce inflammation, while other ingredients offer general hydration rather than directly targeting oily shine. Oily skin needs treatments with ingredients like niacinamide and zinc PCA to control oil production and enhance radiance.
Sources: [The British Journal of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17635508/), [International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/19818086/)

### Which ingredients make this serum a good fit for oily skin?

Panthenyl triacetate and ethyl linoleate help control oil and calm inflammation in your oily skin. To be a better fit for this skin type, a product of this kind needs ingredients like niacinamide, ferulic acid, and zinc PCA to actively target excess shine and enlarged pores.
Sources: [The British Journal of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17635508/), [International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/19818086/)

### What does Dipeptide Diaminobutyroyl Benzylamide Diacetate do for oily skin?

Dipeptide diaminobutyroyl benzylamide diacetate helps smooth out fine lines and wrinkles while improving overall skin texture. For oily skin, a product of this type needs lightweight hydrators and balancing ingredients that refine pores without feeling heavy or greasy.
Sources: [International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41668671/)

### What does Adenosine Triphosphate do for oily skin?

Adenosine Triphosphate is unlikely to help oily skin and may cause unwanted irritation or increased sensitivity. A product for oily skin needs oil-absorbing or balancing ingredients to keep the skin clear and calm.
Sources: [Brain, 2000](https://pubmed.ncbi.nlm.nih.gov/10825361/)

### Where does this serum go in a skincare routine for oily skin?

This treatment serum goes in the evening routine after cleansing and toning, and before moisturizing. Oily skin works best with products that help regulate oil and reduce shine while providing lightweight hydration.

### Can I use this serum with retinol, and in what order?

Yes, you can use this treatment with retinol by applying the treatment first and following with your retinol. The formula is safe and unlikely to cause irritation on oily skin, but an average fit for this skin type also needs ingredients that directly manage excess oil and shine.

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after cleansing and toning. Oily skin works well with a lighter, oil-controlling product that contains ingredients like niacinamide or salicylic acid to help reduce shine.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to cause breakouts for your oily skin, as it has a safe formula with no harsh ingredients. However, it only offers general hydration rather than directly targeting oily shine, so oily skin needs lightweight, oil-balancing ingredients that help control excess sebum.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum). Oleyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for oily skin

- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — S$50.41 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/oily-skin) — High fit — S$28.55 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/oily-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

- Amazon.sg: S$214.57 (https://www.amazon.sg/dp/B00FSBMJHI?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Cyclopentasiloxane, Dipropylene Glycol, Propylene Glycol, Dimethicone, Glycerin, Dimethicone Crosspolymer, Dimethicone Peg-10 15 Crosspolymer, Peg-12 Dimethicone Crosspolymer, Butylene Glycol, Dimethicone Vinyl Dimethicone Crosspolymer, Sodium Phosphate, Panthenyl Triacetate, Magnesium Sulfate, Hydrolyzed Sericin, Ethyl Linoleate, Buddleja Davidii Meristem Cell Culture, Angelica Polymorpha Sinensis Root Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Lactobacillus Panax Ginseng Root Extract Ferment Filtrate, Disodium Acetyl Glucosamine Phosphate, Acetyl Tyrosine, Dimethiconol, Oleyl Alcohol, Proline, Parfum, Tocopherol, Beta-Glucan, Adenosine Triphosphate, Hydrolyzed Protein, Sodium Chloride, Xanthan Gum, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/zo-skin-health/growth-factor-serum/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/zo-skin-health/growth-factor-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/zo-skin-health/growth-factor-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/zo-skin-health/growth-factor-serum/for/oily-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/zo-skin-health/growth-factor-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/zo-skin-health/growth-factor-serum/for/oily-skin