# ZO Skin Health Daily Power Defense for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [ZO Skin Health](https://lovi.care/skincare/sg/brands/zo-skin-health)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your dry and sensitive skin, with glycerin and beta-glucan providing humectant and emollient actions, while safflower palm aminopropanediol esters oil nourishes deeply.
- The inclusion of Arabidopsis Thaliana Extract and Marrubium Vulgare Meristem Cell Culture offers excellent protection against environmental stressors, complementing the general skincare benefits.
- The product is safe for your skin, as it contains no harsh ingredients and poses no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Beta-Glucan, Arabidopsis Thaliana Extract, Tocopheryl Acetate, Palmitoyl Tripeptide-1

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Topical application of photolyase-containing liposomes followed by photoreactivating light decreased UVB-induced dimers by 40-45% and prevented immunosuppression, erythema, and sunburn-cell formation in healthy human subjects. ([Proceedings of the National Academy of Sciences of the United States of America, 2000](https://pubmed.ncbi.nlm.nih.gov/10660687/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of oat beta-glucan ameliorates epidermal hyperplasia and accelerates epidermal barrier recovery by promoting keratinocyte differentiation through dectin-1-mediated ERK and p38 signaling pathways that upregulate CaSR expression. ([International Journal of Biological Macromolecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34237364/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))

## What reviewers say

Based on limited data, this serum is highly regarded for its ability to repair the skin barrier, providing a healthy glow and improved texture. Most users appreciate its lightweight feel and hydrating properties. Some users report experiencing initial irritation or breakouts due to active ingredients, and the high price point is a frequent concern.

- Liked: Barrier repair (mostly mentioned)
- Liked: Lightweight & absorbent (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Anti-aging results (sometimes noted)
- Liked: Versatile hydration (sometimes noted)
- Disliked: Initial irritation (sometimes noted)
- Disliked: Counterfeit risk (rarely noted)
- Disliked: Scent/packaging (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Daily Power Defense work for dry sensitive skin?

This treatment works for your dry sensitive skin, though other products fit it better because they offer stronger hydration and barrier support with ingredients like ceramides and multiple forms of vitamin C.

### Which ingredients make this serum a good fit for dry sensitive skin?

Glycerin and beta-glucan help make this serum a fit for dry sensitive skin by providing moisture and soothing benefits. To work best for this skin type, a product of this type needs rich hydrating and nourishing ingredients, along with ceramides and multiple forms of vitamin C to support moisture retention and skin barrier strength without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Retinol do for dry sensitive skin?

Retinol is often too strong for dry sensitive skin because it may cause scaling and stinging, so a product of this type needs gentle soothing ingredients and extra moisture to keep the skin calm and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### What does Beta-Glucan do for dry sensitive skin?

Beta-glucan helps calm dry, sensitive skin while improving hydration and repairing the skin barrier to keep it soft and smooth. It works well for this skin type because it has soothing and moisturizing properties that are very unlikely to cause irritation.
Sources: [Food Science & Nutrition, 2025](https://pubmed.ncbi.nlm.nih.gov/40291929/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. A product of this type for dry sensitive skin needs extra soothing ingredients and deep nourishing oils to provide better comfort.

### Can I use this serum with vitamin C, and in what order?

You can use this treatment with vitamin C by applying vitamin C first in the morning and saving this treatment for your evening routine. This helps your skin stay calm while getting the full benefits of both products. To work best for dry sensitive skin, a product of this type needs rich nourishing oils, gentle soothing plant extracts, and deep daily hydration.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Because this product is an average fit for dry and sensitive skin, a product of this type needs extra soothing ingredients and rich moisturizers to keep your skin calm and comfortable.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This product is unlikely to clog pores, but the retinol it contains may cause initial irritation or mild purging on dry sensitive skin. A product of this type needs rich moisturizing ingredients like ceramides, hyaluronic acid, and plant oils to keep dry skin feeling soft and calm.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum and limonene). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/dry-sensitive-skin) — High fit — S$50.41 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/sg/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-sensitive-skin) — High fit — S$40.09 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/dry-sensitive-skin) — High fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — S$25.06 at Amazon
- Soothing Toner: [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/sg/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/dry-sensitive-skin) — High fit — S$34.52 at Amazon
- Moisturizer with Sun Protection: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/sg/p/dr-g/green-mild-up-sun/for/dry-sensitive-skin) — Superior fit — S$59.06 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, 1,2-Hexanediol, Dicaprylyl Carbonate, Cetearyl Isononanoate, Glycerin, Pentylene Glycol, Cetearyl Alcohol, Steareth-20, Safflower Palm Aminopropanediol Esters Oil, Laminaria Digitata Extract, Opuntia Ficus-Indica Stem Extract, Arabidopsis Thaliana Extract, Marrubium Vulgare Meristem Cell Culture, Leontopodium Alpinum Meristem Cell Culture, Retinyl Palmitate, Tocopheryl Acetate, Tocopherol, Micrococcus Lysate, Caprylyl Glycol, Hexylene Glycol, Lactose, Galactoarabinan, Schizophyllan, Beta-Glucan, Carbomer, Cellulose, Maltodextrin, C14-22 Alcohols, C12-20 Alkyl Glucoside, Hydroxypropyl Methylcellulose, Disodium Edta, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Parfum, Ultramarines, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/zo-skin-health/daily-power-defense/for/dry-sensitive-skin