# Youth To The People Polypeptide-121 Future Cream for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Youth To The People](https://lovi.care/skincare/sg/brands/youth-to-the-people)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your dry skin, this cream utilizes hydrolyzed hyaluronic acid and niacinamide to deeply hydrate and strengthen your skin barrier, effectively addressing dryness and flakiness.
- The inclusion of ceramides and peptides further supports skin repair and resilience, making it a highly beneficial choice for your skin concerns.
- The formulation is safe for your skin, containing soothing ingredients like aloe barbadensis leaf juice and bisabolol with no harsh or irritating components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Biotech Collagen, Hydrolyzed Hyaluronic Acid, Niacinamide, Acetyl Tetrapeptides, Aloe Barbadensis Leaf Juice

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls. ([International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))

## What reviewers say

Based on a very large amount of data, users with dry and sensitive skin frequently praise this cream for its ability to provide deep, long-lasting hydration without feeling heavy, often describing a "dewy" and "plump" finish. Many appreciate its barrier-strengthening ingredients and lightweight texture under makeup. Some users with oily or acne-prone skin experienced breakouts, and others found the price point too high for the amount of product provided.

- Liked: Deep hydration (mostly mentioned)
- Liked: Lightweight texture (mostly mentioned)
- Liked: Makeup compatibility (often mentioned)
- Disliked: Expensive for size (often mentioned)
- Liked: Soothing formula (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Unhygienic packaging (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Youth To The People Polypeptide-121 Future Cream a great fit for dry skin?

This cream is a great fit because it uses hyaluronic acid and niacinamide to deeply hydrate dry skin and strengthen your skin barrier. Ceramides and peptides help repair the skin, while soothing ingredients like aloe make the formula gentle and safe for daily use.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### Which ingredients make this cream a good fit for dry skin?

This cream is a great fit for dry skin because it uses hydrolyzed hyaluronic acid and niacinamide to deeply hydrate and strengthen your skin barrier. It also includes ceramides, peptides, and soothing aloe to repair dryness and flakiness safely.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### What does Biotech Collagen do for dry skin?

Biotech Collagen helps dry skin by improving skin moisture and hydration when taken daily over several weeks. It also helps make dry skin more smooth and elastic while reducing dryness signs.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26362110/), [Journal of the Science of Food and Agriculture, 2016](https://pubmed.ncbi.nlm.nih.gov/26840887/)

### What does Hydrolyzed Hyaluronic Acid do for dry skin?

Hydrolyzed hyaluronic acid helps dry skin by deeply boosting moisture levels and keeping skin soft and smooth. Clinical studies show that applying it regularly significantly improves skin hydration and helps restore a healthy, comfortable feel.
Sources: [International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34638528/)

### Where does this cream go in a skincare routine for dry skin?

This moisturizing treatment goes in the morning routine after your hydrating toner, and in the evening routine as the final moisturizing step. Using a moisturizer helps lock in hydration and significantly improves dry skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying the moisturizer after your retinol treatment to help soothe and keep dry skin comfortable. Using a barrier-supporting moisturizer alongside active treatments is unlikely to cause irritation and helps maintain skin hydration.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your morning and evening routine to keep dry skin hydrated and comfortable. Daily use helps improve moisture levels and supports your skin barrier over time.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for dry skin?

This cream is unlikely to cause breakouts for dry skin, as shopper complaints about breakouts are low and the formula contains gentle, soothing ingredients without harsh irritants. Studies suggest that its hydrating components maintain a safe profile while improving skin hydration.

### Can I use this cream around the eyes or on my body?

This cream is well suited for dry skin and safely brings deep hydration and barrier repair to the thin skin around the eyes and body.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry skin

- [NEOGEN DERMALOGY Probiotics Youth Repair Cream](https://lovi.care/skincare/sg/p/neogen-dermalogy/probiotics-youth-repair-cream/for/dry-skin) — Superior fit — S$47.90 at Amazon
- [Sulwhasoo Ginseng Renewing Cream Ex](https://lovi.care/skincare/sg/p/sulwhasoo/ginseng-renewing-cream-ex/for/dry-skin) — Superior fit — S$73.41 at Amazon
- [LANEIGE Water Bank Moisture Cream](https://lovi.care/skincare/sg/p/laneige/water-bank-moisture-cream/for/dry-skin) — Superior fit — S$38.31 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — S$25.06 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/propolis-synergy-toner/for/dry-skin) — Superior fit — S$41.07 at Amazon
- SPF: [Thinkbaby Safe Sunscreen SPF 50+](https://lovi.care/skincare/sg/p/thinkbaby/safe-sunscreen-spf-50/for/dry-skin) — Superior fit — S$21.09 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Dicaprylyl Carbonate, Hydrolyzed Hyaluronic Acid, Trimethylolpropane Tricaprylate Tricaprate, Tridecyl Trimellitate, Propanediol, Sh-Polypeptide-121, Polyglyceryl-3 Methylglucose Distearate, Panthenol, Niacinamide, Proline, Tocopheryl Acetate, Aloe Barbadensis Leaf Juice, Hydrolyzed Cannabis Sativa Seed Extract Cannabis Sativa Seed Extract, Hydrolyzed Rice Protein, Hydrolyzed Pea Protein, Salvia Hispanica Seed Extract, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Hibiscus Sabdariffa Fruit Extract, Ammonium Acryloyldimethyltaurate Beheneth-25 Methacrylate Crosspolymer, Hydrolyzed Linseed Seed, Castor Ipdi Copolymer Oil, Ceramide Ap, Ceramide Np, Cetearyl Alcohol, Cetearyl Glucoside, Glycerin, Hydrolyzed Sodium Hyaluronate, Coco-Caprylate Caprate, Dilinoleic Acid Propanediol Pdi Crosspolymer, Benzyl Alcohol, Zingiber Officinale Root Extract, Bisabolol, Caprylyl Glycol, Carbomer, Dimethyl Isosorbide, Dipropylene Glycol, Erythritol, Ethylhexylglycerin, Glucose, 1,2-Hexanediol, Trisodium Ethylenediamine Disuccinate, Glyceryl Monostearate, Phytosphingosine, Polyacrylate Crosspolymer-6, Polysorbate 20, Caprylhydroxamic Acid, Potassium Sorbate, Glycine, Hydroxyacetophenone, Sodium Benzoate, T-Buty Alcohol, Citric Acid, Sodium Citrate, Sodium Lactate, Triheptanoin, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- United Kingdom: https://lovi.care/skincare/uk/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- France: https://lovi.care/skincare/fr/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/youth-to-the-people/polypeptide-121-future-cream/for/dry-skin