# VT Reedle Shot 300 for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [VT](https://lovi.care/skincare/sg/brands/vt)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Offers high suitability for your normal skin as niacinamide and sodium hyaluronate work to repair the skin barrier and provide essential hydration. Hydrolyzed sponge and niacinamide also improve skin texture and tone, addressing your concerns about wrinkles and fine lines.
- Adenosine and Centella Asiatica Extract further support collagen production and skin repair, enhancing the product's effectiveness for your specific skin concerns.
- The product is safe for your normal skin, with no identified risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica, Hyaluron, Niacinamide, Centella Asiatica Extract, Propolis Extract

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical propolis application significantly reduced postoperative pain, hemorrhage, and accelerated wound healing in patients undergoing tonsillectomy compared to a control group. ([Clinical and Experimental Otorhinolaryngology, 2018](https://pubmed.ncbi.nlm.nih.gov/29665628/))
- Topical treatment with ethanol propolis extract resulted in complete mycological and clinical cure in 56.25% of patients with onychomycosis, demonstrating non-toxicity and effective antifungal activity against Trichophyton spp. both in vitro and in patients. ([Frontiers in Microbiology, 2018](https://pubmed.ncbi.nlm.nih.gov/29922236/))

## What reviewers say

Based on a very large amount of data, users report this essence significantly improves skin texture and radiance, acting as a powerful booster for enhanced absorption of other products. It is highly effective for smoothing roughness, minimizing pores, and fading acne scars. However, the unique prickly sensation requires tolerance and may be too harsh for sensitive skin barriers.

- Liked: Smoother skin texture (mostly mentioned)
- Disliked: Intense prickly sensation (mostly mentioned)
- Liked: Enhanced absorption (often mentioned)
- Liked: Radiance and glow (often mentioned)
- Liked: Pore & scar reduction (sometimes noted)
- Disliked: Skin irritation possible (sometimes noted)
- Disliked: Counterfeit product risk (rarely noted)
- Disliked: Temporary purging phase (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes VT Reedle Shot 300 a great fit for mature skin?

VT Reedle Shot 300 is a great fit for mature skin because niacinamide and sodium hyaluronate repair the skin barrier and deliver deep moisture while smoothing out fine lines. Adenosine and centella asiatica extract help boost collagen and repair skin to keep it looking firm and youthful. It is very safe for daily use and is unlikely to cause irritation.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/)

### Which ingredients make this serum a good fit for mature skin?

Niacinamide and sodium hyaluronate make this a great fit by repairing the skin barrier and giving mature skin deep hydration. Ingredients like hydrolyzed sponge, adenosine, and centella asiatica extract also help smooth fine lines and support collagen for a firmer feel.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/)

### What does Centella Asiatica do for mature skin?

Centella asiatica helps mature skin by boosting moisture, keeping it smooth, and supporting collagen to make skin look firmer and less wrinkled. It also helps calm redness and protect skin from daily stress and aging.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516082/), [Scientific Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34188145/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by significantly improving skin hydration, elasticity, and reducing the depth of wrinkles. Regular use of these formulations makes dry skin feel much softer and smoother while helping to diminish the appearance of fine lines over time.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does it go in a skincare routine for mature skin?

VT Reedle Shot 300 goes in your evening routine as a treatment step, used after cleansing and toning and before your moisturizer. It is unlikely to irritate your mature skin, as it helps repair the skin barrier and supports collagen production to address fine lines and wrinkles.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol, applying this product first in your evening routine and following with your retinol. Because this product features ingredients like niacinamide and hyaluronic acid that repair the skin barrier and support hydration, it is unlikely to cause irritation when paired thoughtfully with active ingredients.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### How often should I use it?

VT Reedle Shot 300 is used as an evening treatment step in your routine once every three days or as directed since it contains an intensive micro-needling formula. It is unlikely to cause irritation when used properly, helping to smooth fine lines and improve skin texture over time.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/)

### Can it clog pores, cause breakouts or purging for mature skin?

VT Reedle Shot 300 is unlikely to cause breakouts, but it may cause a low temporary purging phase for mature skin. Reviewers also note an intense prickly sensation during use, though the formula has a safe profile without harsh ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — S$50.41 at Amazon
- [PCA Skin C&E Strength Max](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-strength-max/for/mature-skin) — High fit — S$179.75 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/mature-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

- YesStyle: S$3.85 (https://www.yesstyle.com/en/vt-reedle-shot-300-2-step-mask-1-5g-25g-x-1-sheet/info.html/pid.1128725411?curr=SGD&rco=SG)
Prices checked 17 Oct 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Niacinamide, Butylene Glycol, Macadamia Ternifolia Seed Oil, 1,2-Hexanediol, Ethylhexyl Palmitate, Sodium Acrylate Sodium Acryloyldimethyltaurate Copolymer, Polyisobutene, Hydrolyzed Sponge, Glycereth-26, Ethylhexylglycerin, Caprylyl Glycol, Adenosine, Sodium Polyacrylate, Sodium Hyaluronate, Centella Asiatica Extract, Caprylyl Capryl Glucoside, Sorbitan Oleate, Xanthan Gum, Propolis Extract, Asiaticoside, Madecassoside, Madecassic Acid, Asiatic Acid, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Histidine, Methionine, Cysteine
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/vt/reedle-shot-300/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/vt/reedle-shot-300/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/vt/reedle-shot-300/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/vt/reedle-shot-300/for/mature-skin
- France: https://lovi.care/skincare/fr/p/vt/reedle-shot-300/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/vt/reedle-shot-300/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/vt/reedle-shot-300/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/vt/reedle-shot-300/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/vt/reedle-shot-300/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/vt/reedle-shot-300/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/vt/reedle-shot-300/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/vt/reedle-shot-300/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/vt/reedle-shot-300/for/mature-skin