# Vichy LiftActiv B3 Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Vichy](https://lovi.care/skincare/sg/brands/vichy)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate exfoliation and skin tone evening for your combination skin, as niacinamide and glycolic acid work to regulate oil and smooth texture.
- While it provides general hydration and mild exfoliation, it lacks targeted ingredients like salicylic acid to effectively address your acne, blemishes, and breakouts.
- The product is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like niacinamide and allantoin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Glycerin, Glycolic Acid, Tranexamic Acid, Ascorbyl Glucoside

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

This serum is frequently praised for its lightweight, fast-absorbing formula that effectively targets dark spots, uneven skin tone, and fine lines. Users with various skin types report a brighter, smoother complexion with consistent use over several weeks. Some users find the price point to be high and note that results can take time, with a few experiencing issues with the packaging.

- Liked: Fast absorption (mostly mentioned)
- Liked: Evens skin tone (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Brightening effect (sometimes noted)
- Liked: Gentle formula (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Packaging design (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Vichy LiftActiv B3 Serum work for acne-prone skin?

Vichy LiftActiv B3 Serum works moderately well for acne-prone skin by offering mild smoothing and oil control, though it lacks targeted ingredients like salicylic acid for breakouts. Treatments that fit this skin better need ingredients like salicylic acid, propolis, or zinc PCA to effectively clear blemishes and control oil.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum works for acne-prone skin because niacinamide and glycolic acid help regulate oil and smooth texture. However, it lacks targeted ingredients like salicylic acid to address breakouts, so acne-prone skin needs products containing effective ingredients like salicylic acid, zinc PCA, propolis, or antioxidants to clear blemishes and maintain balance without irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. An acne-prone skin type needs a product of this type that also contains targeted ingredients like salicylic acid to effectively address blemishes and breakouts.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol product, or by using them on alternate nights to keep your skin calm. Because this product offers moderate exfoliation and hydration with soothing ingredients like niacinamide, it is unlikely to irritate your skin when paired carefully with retinol.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

You can use this serum in your evening routine once a week to start, and then carefully use it more often if your skin tolerates it well and sees good results.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

Vichy LiftActiv B3 Serum is unlikely to cause irritation on acne-prone skin, but it lacks salicylic acid and other targeted ingredients needed to effectively clear breakouts and clogged pores.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/acne-prone-skin) — High fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Niacinamide, Hydroxyethylpiperazine Ethane Sulfonic Acid, Glycerin, Hydroxyethyl Urea, Propylene Glycol, Glycolic Acid, Tranexamic Acid, Allantoin, Sodium Hydroxide, Phenoxyethanol, Chlorphenesin, Ascorbyl Glucoside, Caprylyl Glycol, Hydrolyzed Rice Protein, Vitreoscilla Ferment, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Pentylene Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/vichy/liftactiv-b3-serum/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/vichy/liftactiv-b3-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/vichy/liftactiv-b3-serum/for/acne-prone-skin