# Tree of Life Hyaluronic Acid Serum for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Tree of Life](https://lovi.care/skincare/sg/brands/tree-of-life)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your normal skin due to Sodium Hyaluronate and Aloe Barbadensis Leaf Extract, which provide hydration supportive for wrinkles and fine lines.
- Camellia Sinensis Extract and Centella Asiatica Extract offer general skincare benefits, contributing to overall skin health.
- The product is safe for your normal skin, with no risks of irritation from harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Aloe Barbadensis Leaf Extract, Vitamin E Tocopheryl Acetate, Glycerin, Centella Asiatica Extract

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Application of green tea extracts on normal human skin resulted in dose-dependent inhibition of UV-evoked erythema, reduced sunburn cells, protected Langerhans cells, and decreased UV-induced DNA damage compared to untreated UV-exposed skin. ([Journal of the American Academy of Dermatology, 2001](https://pubmed.ncbi.nlm.nih.gov/11209110/))
- Topical application of (-)-epigallocatechin-3-gallate (EGCG) to human skin before UV irradiation decreases UV-induced production of hydrogen peroxide by 68-90% and nitric oxide by 30-100%, inhibits leukocyte infiltration and lipid peroxidation by 41-84%, and restores glutathione levels and glutathione peroxidase activity compared to UV exposure alone. ([Carcinogenesis, 2001](https://pubmed.ncbi.nlm.nih.gov/11181450/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## Why other moisturizers fit mature skin better

- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))

## What reviewers say

Based on a very large amount of data, this serum is a popular, affordable option that provides surface-level hydration and a plumping effect for normal, combination, and oily skin types. Many users appreciate its gentle, botanical-infused formula, though those with sensitive or reactive skin should be cautious due to the inclusion of witch hazel and geranium essential oil.

- Liked: Affordable price (mostly mentioned)
- Liked: Hydrates skin (often mentioned)
- Liked: Lightweight feel (sometimes noted)
- Liked: Plumping effect (sometimes noted)
- Disliked: Fragrance presence (sometimes noted)
- Disliked: Modest results (sometimes noted)
- Disliked: Potential irritant (sometimes noted)
- Disliked: Witch hazel base (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Tree of Life Hyaluronic Acid Serum work for mature skin?

This serum offers moderate moisture for mature skin through ingredients like sodium hyaluronate and aloe vera, which help soften fine lines. While it is safe and gentle, mature skin often benefits more from products packed with targeted anti-wrinkle ingredients and skin-repairing nourishers.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this serum a good fit for mature skin?

Sodium Hyaluronate and Aloe Barbadensis Leaf Extract make this serum a good fit by providing hydration that helps with wrinkles and fine lines. Camellia Sinensis Extract and Centella Asiatica Extract also contribute general skincare benefits and support overall skin health. To fit mature skin even better, a product of this type needs highly effective anti-wrinkle and hydrating ingredients along with skin-repairing components.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### What does Aloe Vera Leaf Extract do for mature skin?

Aloe vera leaf extract helps mature skin by improving moisture and supporting firmness. It aids in boosting hydration and collagen production to keep skin feeling soft and smooth.
Sources: [Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/), [Skin Pharmacology and Physiology, 2016](https://pubmed.ncbi.nlm.nih.gov/28088806/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in the evening routine after cleansing and before moisturizing. Mature skin needs products with richer hydrators and targeted anti-aging actives to properly smooth fine lines and improve firmness.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate your skin and then following with your retinol product. This helps keep your skin soft and smooth while reducing the dryness that sometimes comes with retinol use. To best care for mature skin, a product of this type needs richer nourishing ingredients and barrier-supporting ceramides to deeply smooth and firm.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

This serum is used in the evening for your mature skin routine, as treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure. Some serums of this type can also be used in the morning or twice a day if your skin tolerates them well.

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts on mature skin, as it has a safe profile with no harsh ingredients. However, a product for this skin needs richer nourishing oils and deep hydrators to truly smooth lines and keep dry areas plump.
Sources: [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this serum around the eyes or on my body?

You can use this serum on your body, but the skin around the eyes is much thinner and may need a product with extra firming peptides, low molecular weight hydrating agents, and rich soothing plant oils for the best results.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/sg/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/mature-skin) — Average fit — S$41.73 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin) — High fit — S$23.12 at YesStyle
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/sg/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/mature-skin) — Average fit — S$21.96 at YesStyle

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Witch Hazel, Cassia Angustifolia Polysaccharide Seed Sodium Hyaluronate Seed, Aloe Barbadensis Leaf Extract, Dimethyl Sulfone, Tocopheryl Acetate Vitamin E, Sodium Ascorbyl Phosphate Ascorbic Acid, Jojoba Oil, Pelargonium Graveolens Oil Essential Oil Geranium Oil Essential Oil, Camellia Sinensis Extract, Centella Asiatica Extract, Equisetum Arvense Extract, Dandelion Extract, Geranium Extract, Hydroxyethyl Ethylcellulose, Chondrus Crispus Gum, Sodium Benzoate, Potassium Sorbate, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/tree-of-life/hyaluronic-acid-serum/for/mature-skin