# Theramid Copper Peptide for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Theramid](https://lovi.care/skincare/sg/brands/theramid)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this product features Bifida Lysate Ferment and Glycerin for excellent humectant action and barrier repair, while copper tripeptide-1 and acetyl hexapeptide-1 provide significant anti-aging benefits by smoothing fine lines and wrinkles.
- While it offers general hydration through Sodium Hyaluronate, its primary focus on repair and anti-aging offers less direct support for your main concerns of acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Copper Tripeptide-1, Acetyl Tetrapeptide-2, Sodium Hyaluronate, Bifida Lysate Ferment, Acetyl Glutamine

## What the research says

- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- Copper applied transdermally as a tripeptide on human skin ex vivo permeated the tissue and was retained in amounts potentially effective for treating inflammatory diseases. ([Inflammation Research, 2010](https://pubmed.ncbi.nlm.nih.gov/20703511/))
- Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls. ([International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))

## What reviewers say

A lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.

- Liked: Improves firmness (often mentioned)
- Liked: Lightweight, fast-absorbing (often mentioned)
- Liked: Boosts radiance (sometimes noted)
- Liked: Gentle, non-irritating (sometimes noted)
- Disliked: Hard to combine (sometimes noted)
- Disliked: High silicone content (rarely noted)
- Disliked: No visible results (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Theramid Copper Peptide Serum a great fit for oily acne-prone skin?

Theramid Copper Peptide Serum is a great fit for your oily acne-prone skin because it features Bifida Lysate Ferment and glycerin to repair your skin barrier while copper tripeptide-1 and acetyl hexapeptide-1 smooth fine lines without causing irritation. It is very safe for your skin type since it lacks harsh or prohibited ingredients, though it focuses more on anti-aging and repair than directly treating breakouts.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Bifida lysate ferment and glycerin make this serum a good fit for your oily skin by providing great hydration and repairing your skin barrier without causing irritation. Copper tripeptide-1 and acetyl hexapeptide-1 also help smooth fine lines and wrinkles while remaining very gentle.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/)

### What does Copper Tripeptide-1 do for oily acne-prone skin?

Copper Tripeptide-1 helps calm oily, acne-prone skin by reducing inflammation and protecting against damage, while also improving overall skin barrier health. This ingredient supports tissue repair and helps smooth out skin texture, making it a useful addition for managing breakouts.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Biomaterials Science. Polymer Edition, 2008](https://pubmed.ncbi.nlm.nih.gov/18644225/)

### What does Acetyl Tetrapeptide-2 do for oily acne-prone skin?

Acetyl Tetrapeptide-2 helps firm up the skin, making it feel more resilient. While it is studied for its overall anti-aging effects on skin cells, oily and acne-prone skin generally benefits more from ingredients that balance oil and soothe breakouts.
Sources: [International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. It is unlikely to irritate oily skin due to the absence of harsh ingredients.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the copper peptide treatment first and following with your retinol after it absorbs. This approach helps smooth fine lines while keeping your oily skin comfortable, as the formula is unlikely to cause irritation.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. It has a very safe formula that is unlikely to irritate oily skin.

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for oily skin because it has an excellent safety profile with no harsh ingredients. However, since its main focus is on anti-aging and repair rather than acne, it does not actively treat breakouts.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/oily-acne-prone-skin) — High fit — S$28.55 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-acne-prone-skin) — Superior fit — S$168.51 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/sg/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — S$41.48 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/theramid/copper-peptide/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/theramid/copper-peptide/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/theramid/copper-peptide/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/oily-acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/theramid/copper-peptide/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/theramid/copper-peptide/for/oily-acne-prone-skin