# Theramid Copper Peptide for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Theramid](https://lovi.care/skincare/sg/brands/theramid)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Highly suitable for your combination skin, this product leverages copper tripeptide-1 and bifida lysate ferment to boost collagen and repair your skin barrier, addressing fine lines and wrinkles effectively.
- While it offers excellent hydration and anti-aging benefits, it lacks specialized ingredients to directly target oily shine, which is your main concern.
- The formulation is safe for your combination skin, containing no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/oily-acne-prone-skin): High

## Key ingredients

Copper Tripeptide-1, Acetyl Tetrapeptide-2, Sodium Hyaluronate, Bifida Lysate Ferment, Acetyl Glutamine

## What the research says

- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls. ([International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))

## What reviewers say

A lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.

- Liked: Improves firmness (often mentioned)
- Liked: Lightweight, fast-absorbing (often mentioned)
- Liked: Boosts radiance (sometimes noted)
- Liked: Gentle, non-irritating (sometimes noted)
- Disliked: Hard to combine (sometimes noted)
- Disliked: High silicone content (rarely noted)
- Disliked: No visible results (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Theramid Copper Peptide serum a great fit for combination skin?

Theramid Copper Peptide serum is a great fit for combination skin because it uses copper tripeptide-1 and bifida lysate ferment to boost collagen, repair your skin barrier, and smooth fine lines. It also provides strong hydration while maintaining a very safe profile that is unlikely to cause irritation.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### Which ingredients make this serum a good fit for combination skin?

Copper Tripeptide-1 and Bifida Lysate Ferment make this serum a great fit for your combination skin because they help boost collagen and repair your skin barrier. They improve fine lines while keeping your skin calm and protected without causing irritation.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### What does Copper Tripeptide-1 do for combination skin?

Copper Tripeptide-1 helps calm combination skin, smooth fine lines, and support a strong skin barrier. It protects against sun damage and helps tighten the skin, keeping it looking firm and healthy.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [BioMed Research International, 2015](https://pubmed.ncbi.nlm.nih.gov/26236730/)

### What does Acetyl Tetrapeptide-2 do for combination skin?

Acetyl Tetrapeptide-2 helps strengthen the skin and maintains its firmness across different areas of combination skin. This ingredient is well suited for daily use to support elasticity and keep the skin looking firm.
Sources: [International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/)

### Where does this serum go in a skincare routine for combination skin?

This treatment goes in your evening routine, applied after cleansing and toning and before your moisturizer. Treatments are placed in the evening for simplicity and extra safety around sun exposure, though some may also be used in the morning or twice a day.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it first to give your skin a boost of hydration and repair, followed by your retinol once it is fully absorbed. This combination is generally safe and unlikely to cause irritation, helping to smooth fine lines while keeping your skin barrier protected.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after cleansing and toning and before moisturizing. It is safe for daily use on combination skin, helping to smooth fine lines and strengthen your skin barrier without causing irritation.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on your combination skin because it contains no harsh or prohibited ingredients that could cause irritation. It also features a safe formulation with a low likelihood of adverse reactions.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — S$28.55 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — S$64.81 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — S$28.72 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/theramid/copper-peptide/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/theramid/copper-peptide/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/theramid/copper-peptide/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/theramid/copper-peptide/for/combination-skin
- France: https://lovi.care/skincare/fr/p/theramid/copper-peptide/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/theramid/copper-peptide/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/theramid/copper-peptide/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/theramid/copper-peptide/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/theramid/copper-peptide/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/theramid/copper-peptide/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/theramid/copper-peptide/for/combination-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/theramid/copper-peptide/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/theramid/copper-peptide/for/combination-skin