# the SAEM Power Ampoule for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: the SAEM
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your redness and irritation due to the presence of Centella Asiatica Extract and Panthenol, which provide hydration and soothing effects supportive for your normal skin. Niacinamide and beta-glucan further aid in anti-inflammatory action and barrier repair, enhancing overall skin health.
- Adenosine contributes to smoothing skin texture, offering additional general skincare advantages.
- The product is safe for your normal skin, with no risks of irritation from harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Sodium Hyaluronate, Ceramide Np, Palmitoyl Pentapeptide-4, Centella Asiatica Extract

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))

## What reviewers say

The SAEM Power Ampoule line provides targeted solutions for various skin concerns. The Hydra and Vitamin versions are highly praised for delivering deep hydration and brightening effects, particularly beneficial for dry or dull skin. The Pore Tightening version is divisive; while some users with oily skin achieve a matte finish, a notable number report breakouts or no visible pore reduction. A common issue across all versions is a frequently malfunctioning dropper.

- Disliked: Defective dropper (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Fast absorption (often mentioned)
- Liked: Affordable price (sometimes noted)
- Liked: Brightening effect (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Ineffective on pores (sometimes noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the SAEM Power Ampoule work for sensitive skin?

The SAEM Power Ampoule works as an average fit for sensitive skin, offering moderate hydration and soothing effects through ingredients like Centella Asiatica extract and panthenol. It may help calm redness and irritation, but sensitive skin requires a treatment with potent antioxidants, superior barrier-repairing components, and a total absence of potential irritants like ethanol for optimal results.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Which ingredients make this serum a good fit for sensitive skin?

Centella Asiatica extract and panthenol help calm redness and irritation, while niacinamide and beta-glucan support barrier repair. To work best for sensitive skin, a treatment of this type needs soothing and hydrating ingredients alongside a gentle, allergen-free formula that poses no risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Sensitive skin needs a product of this type to include calming and barrier-repairing ingredients like centella asiatica, panthenol, niacinamide, and ceramides.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment after your retinol product in your evening routine. Sensitive skin needs gentle soothing ingredients like centella asiatica and panthenol, alongside barrier-repairing ceramides, to keep the skin calm and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### How often should I use it?

You can use this treatment in the evening as part of your routine. Products of this type work best for sensitive skin when they include calming plant extracts and barrier-repairing ingredients to keep skin soft and comfortable.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

It may cause breakouts for sensitive skin, as some reviewers note. A product of this type needs gentle, non-clogging soothing ingredients and lightweight hydrators to keep sensitive skin calm and clear.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (ethanol).

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/sensitive-skin) — Average fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethanol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Niacinamide, Methyl Gluceth-20, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Piper Methysticum Stem Extract Root Leaf, Acmella Oleracea Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Centella Asiatica Extract, Panax Ginseng Extract Berry, Corallina Officinalis Extract, Honey Extract, Monascus Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Camellia Sinensis Seed Oil, Camellia Japonica Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Macadamia Ternifolia Seed Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Laurate, Methylpropanediol, Ceramide Np, Sodium Citrate, Sucrose Distearate, Xanthan Gum, Citric Acid, Adenosine, Fructooligosaccharides, Disodium Edta, Beta-Glucan, Polyquaternium-51, Glyceryl Stearate, Butylene Glycol, Bifida Lysate Ferment, Panthenol, Hydrolyzed Hyaluronic Acid, Raffinose, Folic Acid, Cholesterol, Aureobasidium Pullulans Ferment, Tromethamine, Palmitoyl Pentapeptide-4, Nonapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Hexapeptide-9, Hydrogenated Polydecene, Polyglyceryl-10 Oleate, Hydroxyacetophenone, Ethylhexylglycerin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-saem/power-ampoule/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-saem/power-ampoule/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-saem/power-ampoule/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-saem/power-ampoule/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-saem/power-ampoule/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-saem/power-ampoule/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-saem/power-ampoule/for/sensitive-skin
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- Australia: https://lovi.care/skincare/au/p/the-saem/power-ampoule/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-saem/power-ampoule/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-saem/power-ampoule/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-saem/power-ampoule/for/sensitive-skin