# The Ordinary Ascorbyl Glucoside Solution 12% for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [The Ordinary](https://lovi.care/skincare/sg/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate brightening for your combination skin due to Ascorbyl Glucoside, which provides antioxidant protection and helps even skin tone, while Propanediol offers humectant action.
- While the formula is generally supportive, its primary benefits are not directly targeted at addressing your acne, blemishes, and breakouts.
- The safety profile is excellent, with no risks of irritation for your acne-prone skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbyl Glucoside, Vitamin C Derivative, Propanediol, Xanthan Gum, Dimethyl Isosorbide

## What the research says

- Topical application of 1,3-propanediol at various concentrations, alone or combined with butylene glycol and/or glycerol, increased skin hydration and reduced trans epidermal water loss in 30 healthy female subjects over an 8-hour period, with the 15% concentration and the addition of glycerol providing greater benefits. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Treatment with ascorbyl glucoside-arginine complex lotion significantly decreased pigmentation scores and melanin index while increasing lightness in solar lentigos of Japanese females compared to placebo over 24 weeks. ([International Journal of Molecular Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/39769217/))
- A mixture of propanediol, xylitol, and caprylic acid demonstrated in vitro antimicrobial activity against C. acnes and S. aureus, reduced 5-alpha reductase expression, and decreased skin oiliness, porphyrin, and inflammatory lesions in participants over 28 days. ([Molecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34771112/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Sustainable cosmetic products formulated with renewable PDO-based emulsifiers showed equivalent performance in sensory and moisturization evaluations compared to those formulated with petroleum-derived PEG-based emulsifiers. ([Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/29465392/))
- Biodegradable wound dressings functionalized with silver nanoparticles showed >99% pathogen growth inhibition, bactericidal effects, free radical scavenging, reduced inflammatory response in macrophages, and accelerated wound healing in animals. ([International Journal of Biological Macromolecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35780920/))
- A topical xanthan gum nanogel containing gamma-oryzanol-loaded nanostructured lipid carriers and nanosized TiO2 and MBBT filters demonstrated high photoprotection with an SPF of 34 and no skin irritation or sensitization in a rat model. ([Pharmaceuticals, 2023](https://pubmed.ncbi.nlm.nih.gov/37242453/))
- Dense chitosan-xanthan membranes associated with multipotent mesenchymal stromal cells accelerated wound healing in Wistar rats compared to untreated conditions, demonstrating safety and feasibility for dermo-epidermal wound treatment. ([Journal of Biomaterials Applications, 2015](https://pubmed.ncbi.nlm.nih.gov/25281644/))

## Why other serums fit acne-prone skin better

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

Users frequently praise this serum for brightening dull complexions and evening skin tone, noting its gentle formulation suitable for sensitive or oily skin. While its lightweight texture and stable formula are appreciated, many users report a sticky finish and that results require patience compared to more potent alternatives.

- Liked: Affordable (often mentioned)
- Liked: Brightens & evens tone (often mentioned)
- Liked: Gentle & non-irritating (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: Sticky/tacky finish (often mentioned)
- Liked: Stable formula (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Disliked: Breakouts (rarely noted)
- Disliked: Pilling (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does The Ordinary Ascorbyl Glucoside Solution work for acne-prone skin?

This product is an average fit for your acne-prone skin because its main benefits brighten skin tone rather than directly target breakouts, though it is very safe and unlikely to cause irritation. To work better for this skin, a treatment needs effective ingredients like niacinamide and propolis or zinc pca that help clear blemishes while keeping your skin balanced and hydrated without excess oil.
Sources: [Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/), [International Journal of Molecular Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/39769217/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum works for your skin because Ascorbyl Glucoside helps even your skin tone and Propanediol keeps your face hydrated. However, it is only an average fit for your acne-prone skin because it lacks specific ingredients like niacinamide and propolis that directly target breakouts and blemishes.
Sources: [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/37699769/), [Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/)

### What does Ascorbyl Glucoside do for acne-prone skin?

Ascorbyl Glucoside helps acne-prone skin by providing antioxidant protection and supporting overall skin clarity. Vitamin C derivatives like this are known to improve inflammatory skin disorders and help keep skin calm.
Sources: [Journal of Cosmetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/23174055/), [International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/34679221/)

### What does Vitamin C do for acne-prone skin?

Vitamin C helps protect acne-prone skin and calm redness while working to fade dark spots left behind by breakouts. It is unlikely to cause irritation and may improve overall skin tone when used consistently in your routine.
Sources: [Giornale Italiano Di Dermatologia E Venereologia, 2014](https://pubmed.ncbi.nlm.nih.gov/25068233/), [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39231081/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after your cleansing toner and before your moisturizer. It is unlikely to cause irritation for your acne-prone skin, though it does not directly target breakouts and blemishes.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the Vitamin C derivative first in your routine and following it with retinol, provided your skin is comfortable with both. The formula has an excellent safety profile and is unlikely to cause irritation for your acne-prone skin. However, since this product is not directly targeted at blemishes, acne-prone skin needs products containing targeted blemish-fighting ingredients and retinoids to effectively treat breakouts.
Sources: [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this serum?

You can use this serum in the evening, applying it once a day or a few times a week as your skin adjusts. It is unlikely to cause irritation for your acne-prone skin, though acne-prone skin also needs targeted blemish-fighting ingredients to see the best results.
Sources: [Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to cause irritation for your acne-prone skin because it lacks harsh ingredients, though a few reviewers note a rare chance of breakouts. Acne-prone skin needs a treatment that directly targets blemishes and excess oil with specialized active ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/acne-prone-skin) — High fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

- YesStyle: S$34.53 (https://www.yesstyle.com/en/the-ordinary-ascorbyl-glucoside-solution-12-30ml/info.html/pid.1118152284?curr=SGD&rco=SG)
Prices checked 13 Oct 2026.

## Ingredients

Water, Ascorbyl Glucoside, Propanediol, Aminomethyl Propanol, Triethanolamine, Isoceteth-20, Xanthan Gum, Dimethyl Isosorbide, Ethoxydiglycol, Trisodium Ethylenediamine Disuccinate, 1,2-Hexanediol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-ordinary/ascorbyl-glucoside-solution-12/for/acne-prone-skin