# The INKEY List Polyglutamic Acid Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Superior · Safety: High.

Page: https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [The INKEY List](https://lovi.care/skincare/sg/brands/the-inkey-list)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for sensitive skin.

## Why this fit

- Highly suitable for your normal skin, this serum effectively addresses redness and irritation with a high concentration of polyglutamic acid, which provides excellent hydration and soothing effects.
- Dimethicone further enhances skin comfort by offering emollient action, complementing the humectant properties of polyglutamic acid.
- The formulation is safe for your sensitive skin, as it lacks any harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/oily-acne-prone-skin): High

## Key ingredients

Polyglutamic Acid, Glycerin, Dimethicone, Butylene Glycol, Rice Bran Extract

## What the research says

- Poly-gamma-glutamic acid derived from a novel Bacillus subtilis strain dose-dependently increased skin barrier markers, hyaluronic acid synthesis, and aquaporin 3 expression in keratinocytes, and elevated filaggrin, involucrin, CD44, and aquaporin 3 expression in a reconstructed skin model compared to the control. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/))
- Curcumin-loaded polyglutamic acid and gum arabic electrospun nanofibers accelerated wound healing, increased TGF-beta1 and VEGF expression, reduced inflammatory factors, and enhanced re-epithelialization and tissue regeneration in a mouse model with acute full-thickness skin defects. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38554903/))
- Petrolatum-based skin protectants demonstrated protection against irritants and maceration while providing skin hydration, whereas dimethicone and zinc oxide products showed varying or limited performance across parameters among 18 healthy volunteers compared to positive and negative controls. ([Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/))
- Polyglutamic acid and polylysine composite hydrogels promote wound repair and hemostasis through high water absorption, bioadhesion, calcium ion-mediated coagulation factor activation, and inherent antibacterial properties in a deep skin defect model. ([Macromolecular Bioscience, 2021](https://pubmed.ncbi.nlm.nih.gov/33656254/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Externally applied substances such as ceramides, hyaluronic acid, licorice extracts, dimethicone, petrolatum, and paraffin wax treat skin disease resulting from damage to the skin barrier. ([Clinics in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22507050/))
- Topical gel and cream formulations containing niosomes entrapped with rice bran bioactive compounds improved skin hydration, lightening, thickness, roughness, and elasticity in 30 human volunteers over 28 days compared to baseline. ([Pharmaceutical Biology, 2012](https://pubmed.ncbi.nlm.nih.gov/22235888/))
- Gel and cream formulations containing rice bran bioactive compounds entrapped in niosomes increased in vitro antioxidant activity (ORAC values of 20-28 micromol TE/g versus 16-18 micromol TE/g for placebo), enhanced lipid peroxidation inhibition in human sebum by about 1.5 times, and improved in vivo human skin hydration by approximately 3 to 30% depending on the measurement technique. ([Journal of Nanoscience and Nanotechnology, 2011](https://pubmed.ncbi.nlm.nih.gov/21449379/))
- Stirring Nukadoko fermented rice bran beds by hand leads to temporary settlement of microorganisms on human skin with quick shedding. ([FEMS Microbiology Letters, 2023](https://pubmed.ncbi.nlm.nih.gov/37960971/))

## What reviewers say

Based on a very large amount of data, this serum is frequently praised by users with dry or dehydrated skin for its ability to deeply hydrate and create a smooth, glass-like finish that works well under makeup. Many users find it superior to hyaluronic acid for plumping fine lines. A significant number of reviewers, however, note a strong chemical scent and a pump dispenser that can be difficult to control.

- Liked: Deep hydration (mostly mentioned)
- Liked: Excellent makeup base (often mentioned)
- Liked: Smooth/silky finish (often mentioned)
- Disliked: Unpleasant scent (often mentioned)
- Liked: Plumping effect (sometimes noted)
- Disliked: Poor packaging (sometimes noted)
- Disliked: Skin irritation (rarely noted)
- Disliked: Sticky feel (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes The INKEY List Polyglutamic Acid Serum a great fit for sensitive skin?

This serum is a great fit because it uses polyglutamic acid and glycerin to deliver deep hydration while calming redness and irritation. Dimethicone further helps keep skin soft and comfortable, and the formula is free of harsh ingredients that might upset sensitive skin.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### Which ingredients make this serum a good fit for sensitive skin?

Polyglutamic acid and glycerin make this serum a great fit by providing deep hydration, while dimethicone adds comfort and helps soothe redness. The formula lacks harsh ingredients, making it very safe for easily irritated skin.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### What does Polyglutamic Acid do for sensitive skin?

Polyglutamic acid helps keep sensitive skin deeply hydrated by boosting moisture and supporting the outer skin barrier. It is unlikely to cause irritation and may leave dry or delicate skin feeling soft and smooth.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Acta Dermato-venereologica, 1999](https://pubmed.ncbi.nlm.nih.gov/10598752/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after your toner and before your moisturizer. Applying it at night helps keep things simple and safe for your skin while delivering deep hydration and calming redness.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### Can I use this serum with hyaluronic acid, and in what order?

Yes, you can use this serum with hyaluronic acid by applying the thinner texture first or mixing them together. Both ingredients draw in moisture to make your skin soft and smooth, and this formula is unlikely to irritate sensitive skin.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### How often should I use this serum?

This serum is a great fit for your sensitive skin and is gentle enough to use daily in your evening routine. Regular application helps keep skin calm, deeply hydrated, and comfortable.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts or clog pores for sensitive skin, as its formulation lacks harsh or irritating ingredients. It helps keep skin calm and hydrated while supporting comfort.
Sources: [International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/)

### Can I use this serum around the eyes or on my body?

Yes, you can use this serum around the eyes and on your body because its gentle formula lacks harsh ingredients that could trigger irritation. It helps lock in moisture and calm redness, making it safe for delicate areas like the eyelids and the thinner skin found across various body regions.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/sg/p/revision-skincare/hydrating-serum/for/sensitive-skin) — High fit — S$127.77 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/sg/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/sensitive-skin) — High fit — S$35.27 at YesStyle
- [Isntree Green Tea Fresh Serum](https://lovi.care/skincare/sg/p/isntree/green-tea-fresh-serum/for/sensitive-skin) — High fit — S$17.18 at YesStyle

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

- Amazon.sg: S$34.59 (https://www.amazon.sg/dp/B09N9ZNP9M?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Dimethicone, Butylene Glycol, Bis-Peg-12 Dimethicone, Glycerin, Polymethylsilsesquioxane, Polysilicone-11, Phenoxyethanol, Polyglutamic Acid, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Propanediol, Coco-Glucoside, Sodium Benzoate, Hydroxyethylcellulose, Polysorbate 80, Ethylhexylglycerin, Potassium Sorbate, Decyl Glucoside, Dimethylacrylamide Acrylic Acid Polystyrene Ethyl Methacrylate Copolymer, Sorbitan Oleate, Trisodium Ethylenediamine Disuccinate, Caprylyl Glycol, Hexylene Glycol, Rice Bran Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-inkey-list/polyglutamic-acid-serum/for/sensitive-skin