StriVectin Contour Restore Tightening & Sculpting Face Cream for sensitive skin

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Questions and answers

What the research says

• Topical myristyl nicotinate increased skin cell NAD, stratum corneum thickness, epidermal thickness, epidermal renewal, minimal erythemal dose, and barrier resistance while reducing transepidermal water loss in subjects with photodamaged skin compared to placebo.

  Experimental Dermatology, 2007

• Cosmetic products containing 4-t-butylcyclohexanol demonstrated a faster and more pronounced soothing effect on capsaicin-induced burning compared to those containing acetyl dipeptide-1 cetyl ester in volunteers with sensitive skin.

  Journal of the European Academy of Dermatology and Venereology, 2016

• Prior and concurrent use of myristyl nicotinate with retinoic acid therapy for facial photodamage mitigated barrier impairment, reduced side-effects, and improved tolerability without interfering with clinical efficacy in female subjects.

  Experimental Dermatology, 2007

• A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.

  The Journal of Dermatological Treatment, 2017

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells.

  International Journal of Cosmetic Science, 2025

• Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months.

  The Journal of Dermatology, 2008

• Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants.

  International Journal of Molecular Sciences, 2026

• Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts.

  International Journal of Molecular Sciences, 2021

• Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy.

  Journal of Cosmetic Dermatology, 2021

• Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups.

  Dermatology and Therapy, 2023

• Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment.

  The Journal of Dermatology, 2022

Ingredients

Water, Neopentyl Glycol Diethylhexanoate, C12-15 Alkyl Benzoate, Glycol Distearate, Palmitic Acid, Glycerin, Stearic Acid, Undecane, Cetearyl Alcohol, Myristyl Nicotinate, Cetyl Alcohol, Acetyl Dipeptide-1 Cetyl Ester, Beta-Glucan, Thymus Vulgaris Leaf Extract Flower, Paeonia Albiflora Root Extract, Commiphora Mukul Extract Resin, Tetrahydrodiferuloylmethane, Ornithine, Glycolipids, Butyrospermum Parkii Butter Shea Butter, Sodium Hyaluronate, Sucrose Palmitate, Adenosine, Hydroxyethylcellulose, Allantoin, Panthenol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Potassium Cetyl Phosphate, Caprylic Capric Triglyceride, Levulinic Acid, Glyceryl Caprylate, Butylene Glycol, Tridecane, Propanediol, Isostearyl Isostearate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Linoleate, Pentylene Glycol, Polysorbate 60, Cetyl Stearate, Lecithin, Tocopherol, Caprylhydroxamic Acid, Sorbitan Laurate, Disodium Edta, Ethylhexylglycerin, Caprylyl Glycol, Parfum, Citric Acid, P-Anisic Acid, Benzyl Alcohol, Sodium Hydroxide, Phenoxyethanol, Potassium Sorbate, Limonene, Citral

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.