# SpaLife retinol night serum for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [SpaLife](https://lovi.care/skincare/sg/brands/spalife)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Suitable for normal skin due to the presence of retinol for desquamation regulation and hyaluronic acid for humectant action, this serum offers moderate skin treatment by promoting skin renewal and hydration.
- While it provides general skincare benefits like hydration, these are mostly supportive and not directly targeted at your primary concerns of wrinkles and fine lines.
- The safety profile is good, with no risks of irritation for your normal skin due to the absence of harsh ingredients and the inclusion of soothing hyaluronic acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/dry-sensitive-skin): Warning
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Hyaluronic Acid, Glycerin

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## Why other serums fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

The product is designed to target fine lines, uneven skin texture, and dark spots through a lightweight, retinol-infused formula. Because there is a lack of consumer feedback, its real-world efficacy for specific skin conditions remains unverified by user experience. This summary is based on limited data.

- Liked: Adds luminosity (rarely noted)
- Liked: Improves texture (rarely noted)
- Liked: Lightweight formula (rarely noted)
- Disliked: Limited availability (rarely noted)
- Disliked: Potential irritation (rarely noted)
- Disliked: Weak active ingredients (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does SPALIFE Retinol Night Serum work for mature skin?

This serum works moderately well for mature skin by helping with hydration and skin renewal, though other products target wrinkles and fine lines more directly. To truly smooth mature skin, a product needs potent antioxidants, peptides, and high-quality ingredients that specifically target aging concerns.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this serum a good fit for mature skin?

Retinol and hyaluronic acid make this serum a good fit for mature skin by renewing the skin and keeping it hydrated. To best care for mature skin, a product of this type needs high concentrations of potent antioxidants, peptides, and skin-repairing ingredients that effectively target wrinkles and fine lines while offering exceptional safety and no risk of irritation.

### What does Retinol do for mature skin?

Retinol helps smooth out fine lines and wrinkles while improving overall skin thickness and firmness over time. It may also cause temporary dryness, scaling, or stinging as your skin gets used to it.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Putting it at night keeps it simple and avoids extra safety concerns around sun exposure.

### Can I use it with vitamin C, and in what order?

You can use this serum with vitamin C by applying vitamin C in the morning and this retinol serum at night to keep your skin calm and avoid irritation. Mature skin needs targeted anti-aging ingredients like potent antioxidants and higher concentrations of retinol to effectively smooth fine lines and wrinkles.

### How often should I use this serum?

Use this serum in your evening routine. A mature skin product of this type needs targeted ingredients like potent retinoids and peptides to effectively smooth fine lines and wrinkles while boosting collagen.

### Can it clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to clog pores or cause breakouts for mature skin, and it has a good safety profile with a low risk of irritation. However, because it works for this skin type only moderately well, a mature skin product of this type needs stronger active ingredients and targeted wrinkle-fighting components to properly address fine lines.

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for mature skin

- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — S$50.41 at Amazon
- [PCA Skin C&E Strength Max](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-strength-max/for/mature-skin) — High fit — S$179.75 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/mature-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Peg Ppg-17 6 Copolymer, Butylene Glycol, Caprylic Capric Triglyceride, Caprylyl Glycol, Agar, Calcium Alginate, Carbon Black, Ci 60725, Glycerin, Propylene Glycol, Caprylhydroxamic Acid, Phenoxyethanol, Ethylhexylglycerin, Carbomer, Triethanolamine, Retinol, Xanthan Gum, Hyaluronic Acid, Disodium Edta, Peg-40 Hydrogenated Castor Oil, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/spalife/retinol-night-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/spalife/retinol-night-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/spalife/retinol-night-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/spalife/retinol-night-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/spalife/retinol-night-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/spalife/retinol-night-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/spalife/retinol-night-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/spalife/retinol-night-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/spalife/retinol-night-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/spalife/retinol-night-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/spalife/retinol-night-serum/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/spalife/retinol-night-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/spalife/retinol-night-serum/for/mature-skin