# Skin Better Science Alto Advanced Defense and Repair Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Skin Better Science](https://lovi.care/skincare/sg/brands/skin-better-science)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- Offers excellent protection against environmental stressors due to the presence of antioxidants like Ergothioneine and Superoxide Dismutase, which are beneficial for your dry and sensitive skin. Glycerin and Sodium PCA provide hydration, supporting your dry or flaky skin concerns.
- The inclusion of barrier repair ingredients such as Ceramide NP, Ceramide AP, and Ceramide EOP further enhances suitability for dry skin by aiding in moisture retention.
- The product is safe for your dry and sensitive skin as it contains no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Superoxide Dismutase, Tetrahexyldecyl Ascorbate, Carnosine, Ceramide Ap

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Treatment with a Rhodiola rosea extract and L-carnosine-associated compound produced in vivo protective effects on skin barrier function and positive subjective responses in 124 volunteers with sensitive skin compared to placebo. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18482014/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- A night cream containing melatonin, carnosine, and Helichrysum italicum extract reduced oxidative stress ex vivo and improved hydration, reduced transepidermal water loss, decreased wrinkles and spots, and lowered skin reactivity in 117 individuals over up to 12 weeks of nightly use. ([Dermatology and Therapy, 2020](https://pubmed.ncbi.nlm.nih.gov/32915393/))
- Supramolecular carnosine improves skin reactivity, upregulates Nrf2 expression, activates antioxidant defenses, and reduces AGE levels while demonstrating whitening efficacy in cells and clinical tests compared to conventional carnosine. ([Advanced Healthcare Materials, 2024](https://pubmed.ncbi.nlm.nih.gov/39279568/))
- A targeted skincare regimen containing active ingredients such as rhodophyceae extract, ergothioneine, and L-carnosine significantly reduced transepidermal water loss by 24.09%, improved skin elasticity, and decreased redness, dryness, and desquamation in thirty-five female Chinese participants over 4 weeks following advanced optimal pulse technology treatment. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40497421/))

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Alto Advanced Defense and Repair Serum a great fit for dry sensitive skin?

This serum is a great fit because it contains potent antioxidants like superoxide dismutase to protect your skin, while glycerin and sodium PCA draw in moisture to calm dryness. It also includes ceramides to help lock in hydration, and its gentle formula is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for dry sensitive skin?

This serum is a great fit for your dry sensitive skin because it contains glycerin and sodium PCA to boost hydration, along with ceramides that help lock in moisture. It also features powerful antioxidants like superoxide dismutase and ergothioneine to protect your skin without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Superoxide Dismutase do for dry sensitive skin?

Superoxide dismutase helps calm dry sensitive skin by reducing oxidative stress and defending against daily environmental damage. It supports the skin barrier and is unlikely to cause irritation.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/), [Evidence-based Complementary and Alternative Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32908567/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment serum goes in the evening routine after your toner and before your moisturizer. Applying it at night provides extra safety around sun exposure, and the formula is unlikely to irritate your dry and sensitive skin since it contains no harsh ingredients.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first in your evening routine, allowing it to absorb before putting on your retinol. This approach helps protect your dry and sensitive skin from irritation while delivering antioxidants and hydration.

### How often should I use this serum?

This serum is used in your evening routine, applied after toning and before moisturizing. You can start using it once a day or a few times a week depending on how your skin feels.

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores, cause breakouts, or lead to purging on dry sensitive skin. Its gentle formula contains no harsh or prohibited ingredients that could cause irritation.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/dry-sensitive-skin) — High fit — S$50.41 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/sg/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-sensitive-skin) — High fit — S$40.09 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/dry-sensitive-skin) — High fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — S$25.06 at Amazon
- Soothing Toner: [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/sg/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/dry-sensitive-skin) — High fit — S$34.52 at Amazon
- Moisturizer with Sun Protection: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/sg/p/dr-g/green-mild-up-sun/for/dry-sensitive-skin) — Superior fit — S$59.06 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Acacia Decurrens Wax Flower, Acacia Senegal Gum, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Water, Arabidopsis Thaliana Extract, Arginine, Benzylidene Dimethoxydimethylindanone, Bisabolol, Buddleja Officinalis Flower Extract, Butylene Glycol, Camellia Sinensis Leaf Extract, Carbomer, Carnosine, Ceramide Ap, Ceramide Eop, Ceramide Np, Cetearyl Alcohol, Ceteth-20 Phosphate, Chlorogenic Acids, Cholesterol, Citric Acid, Coffea Arabica Extract Cell Leaf Coffee Extract Cell Leaf, Crocus Sativus Extract Cell Leaf Culture, Curcuma Longa Root Extract, Dextran, Dicetyl Phosphate, Diisostearyl Malate, Dimethyl Isosorbide, Ergothioneine, Ethylhexyl Olivate, Ethylhexylglycerin, Euterpe Oleracea Fruit Extract, Glycerin, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Helianthus Annuus Wax Seed Sunflower Wax Seed, Hydrolyzed Sodium Hyaluronate, Jojoba Esters, Lauryl Lactate, Lecithin, Linoleic Acid, Linolenic Acid, Methyl Gluceth-20, Micrococcus Lysate, Niacinamide, Olea Europaea Fruit Extract Olive Fruit Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Pentylene Glycol, Phenoxyethanol, Phytosphingosine, Plankton Extract, Polyglycerin-3, Propanediol, Propanediol Dicaprylate Caprate, Pyrroloquinoline Quinone Allyl Ester, Ricinoleth-40, Sea Whip Extract, Sodium Hydroxide, Sodium Lauroyl Lactylate, Sodium Pca, Sodium Phytate, Steareth-2, Superoxide Dismutase, Tetrahexyldecyl Ascorbate, Theobroma Cacao Seed Extract, Tocopherol, Tocopheryl Acetate, Trifluoroacetyl Tripeptide-2, Ubiquinone, Vitis Vinifera Seed Extract Grape Seed Extract, Xanthan Gum, Zingiber Officinale Root Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/skin-better-science/alto-advanced-defense-and-repair-serum/for/dry-sensitive-skin