# REJURAN DUAL EFFECT AMPOULE for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [REJURAN](https://lovi.care/skincare/sg/brands/rejuran)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as niacinamide helps regulate sebum and hyaluronic acid provides hydration, but it lacks stronger oil-controlling ingredients for optimal results.
- The inclusion of Bisabolol and Calendula Officinalis Flower Extract offers soothing benefits, which are supportive for general skincare needs.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract

## What the research says

- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- A blackberry and dill extract combination synergistically increased skin elasticity and induced elastogenesis compared to each ingredient alone and placebo. ([International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/32583541/))
- Tropical highland blackberry juice reduced UVB-mediated DNA damage and increased apoptosis in human epidermal keratinocytes and a reconstituted skin equivalent model. ([Photochemistry and Photobiology, 2013](https://pubmed.ncbi.nlm.nih.gov/23711186/))
- Strawberry and blackberry crude extracts, anthocyanin-enriched fractions, and proanthocyanidin-enriched fractions demonstrated anti-inflammatory effects through ROS reduction, gene expression inhibition, and NO suppression, while anthocyanin fractions promoted fibroblast migration in vitro. ([Food Research International, 2019](https://pubmed.ncbi.nlm.nih.gov/31108769/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Topical application of Glycyrrhiza glabra and Sophora japonica flavonoid-rich fractions individually and in combination significantly increased the wound healing rate and reduced oxidative stress compared to wound and Nolaver-treated groups. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37049756/))
- Topical application of Calendula officinalis extract cream significantly improved skin hydration and firmness (reflected in significant changes in R0 and R6 parameters) in 21 healthy human volunteers compared to a base cream. ([Acta Poloniae Pharmaceutica, 2011](https://pubmed.ncbi.nlm.nih.gov/21928714/))
- Treatment with standardized extract of Calendula officinalis L. led to a shorter epithelization time and faster healing speed compared to mineral oil in patients with acute skin loss wounds of the hand and fingers healing by secondary intention. ([Tissue Barriers, 2022](https://pubmed.ncbi.nlm.nih.gov/34674610/))
- Topical administration of Calendula provides weak evidence of effectiveness in acute and chronic wounds compared to standard treatments based on a narrative review of available trials. ([Wounds, 2008](https://pubmed.ncbi.nlm.nih.gov/25941793/))

## Why other moisturizers fit oily acne-prone skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## What reviewers say

This ampoule is widely praised for delivering the "glass skin" look, with users reporting immediate improvements in hydration, radiance, and skin texture. It is particularly favored by those with aging or damaged skin for its ability to smooth fine lines and repair the skin barrier using its signature salmon DNA (PDRN) formula, though its high price point is a common contention.

- Liked: Instant Glow (mostly mentioned)
- Disliked: High price point (mostly mentioned)
- Liked: Deep Hydration (often mentioned)
- Liked: Texture Smoothing (often mentioned)
- Disliked: Packaging issues (often mentioned)
- Liked: Fast Absorption (sometimes noted)
- Liked: Soothing & Repair (sometimes noted)
- Disliked: Breakouts/Irritation (rarely noted)
- Disliked: Heavy/Sticky finish (rarely noted)
- Disliked: Not hydrating enough (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Rejuran Dual Effect Ampoule work for oily acne-prone skin?

This moisturizing treatment works moderately well for your oily acne-prone skin, as niacinamide helps control oil and hyaluronic acid provides hydration without clogging pores. Bisabolol and calendula extract help calm your skin with a low risk of irritation. A product of this type needs stronger oil-controlling ingredients, lightweight ceramides, and targeted blemish-fighting components for an optimal fit on oily skin.

### Which ingredients make this ampoule a good fit for oily acne-prone skin?

Niacinamide helps manage oil, while hyaluronic acid gives light hydration, and bisabolol and calendula flower extract soothe skin safely. Oily acne-prone skin needs stronger oil-controlling ingredients, lightweight hydration without clogged pores, and pore-balancing agents.

### What does Blackberry Leaf Extract do for oily acne-prone skin?

Blackberry Leaf Extract helps calm oily, acne-prone skin by soothing irritation and balancing everyday shine. Its natural properties keep pores clear and help your skin feel fresh and smooth throughout the day.

### What does Licorice Extract do for oily acne-prone skin?

Licorice extract helps calm oily, acne-prone skin by reducing redness and fighting bacteria linked to breakouts. It may also lower skin stress and help keep pores clear when used regularly.
Sources: [Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/)

### Where does this ampoule go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing. Oily acne-prone skin needs a product of this type that also includes stronger oil-controlling ingredients for optimal results.

### Can I use this ampoule with retinol, and in what order?

Yes, you can use this ampoule with retinol to keep your skin calm and hydrated while you treat it. Apply the ampoule before your retinol at night to help make your skin more comfortable, as a moisturizing treatment works well to support skin barrier recovery.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this ampoule?

You can use this treatment in your evening routine for simplicity and extra safety around sun exposure. It is safe for your oily skin and is unlikely to cause irritation, but an oily skin type needs stronger oil-controlling ingredients for optimal results.

### Can this ampoule clog pores, cause breakouts or purging for oily acne-prone skin?

This ampoule is unlikely to cause breakouts, as it is safe for your skin with no harsh ingredients and includes soothing components. However, this product of this type needs stronger oil-controlling ingredients to work best for oily acne-prone skin.

### Can I use this ampoule around the eyes or on my body?

You can use this moisturizing treatment around the eyes or on your body, as it has a very good safety profile for the skin. However, an average fit for oily acne-prone skin means this type of product needs stronger oil-controlling ingredients for optimal results.

### Is this ampoule fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/sg/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-acne-prone-skin) — High fit — S$41.73 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/sg/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-acne-prone-skin) — High fit — S$21.96 at YesStyle
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin) — Average fit — S$23.12 at YesStyle

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-acne-prone-skin) — Superior fit — S$168.51 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/sg/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — S$41.48 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Blackberry Leaf Extract, Glycyrrhiza Glabra Extract Licorice Extract, Calendula Officinalis Flower Extract, Aloe Barbadensis Leaf Juice, Blueberry Fruit Extract, Morus Nigra Fruit Extract, Peg-6, Glycerin, Water, Hyaluronic Acid, Niacinamide, Dipropylene Glycol, Butylene Glycol, 1,2-Hexanediol, Carbomer, Gerotine Hydrolyzed Dna, Hydrolyzed Dna, Xanthan Gum, Polysorbate 20, Adenosine, Tocopheryl Acetate, Bisabolol, Arbutin, Ethylhexylglycerin, Caprylyl Glycol, Hexylene Glycol, Trehalose, Urea, Serine, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Pullulan, Disodium Phosphate, Potassium Phosphate, Squalane, Hydrogenated Lecithin, Ceramide Np, Oleic Acid, Inulin Lauryl Carbamate, Cholesterol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/rejuran/dual-effect-ampoule/for/oily-acne-prone-skin