# Paula's Choice Pro-Collagen Multi-Peptide Booster for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Paula's Choice](https://lovi.care/skincare/sg/brands/paula-s-choice)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your normal skin, as Glycerin and Sodium Hyaluronate provide excellent humectant action while Palmitoyl Tripeptide-5 stimulates collagen for plumping.
- The formula also addresses your redness and irritation with Palmitoyl Tripeptide-5 and Polygonum Bistorta Root Extract, which soothe and reduce inflammation.
- The product is safe for your sensitive skin, containing no harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/oily-acne-prone-skin): Average

## Key ingredients

6x Peptide Complex, Sodium Hyaluronate, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Palmitoyl Tripeptide-5

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- A cosmetic cream with 6% standardized wild apple fruit extract and a conventional emulsifier demonstrated stable antioxidant activity of 19.25 %RSC, increased skin moisturization, and a decreased melanin index by -31.40 without causing skin irritation. ([International Journal of Cosmetic Science, 2019](https://pubmed.ncbi.nlm.nih.gov/31050807/))
- Postresurfacing use of a tripeptide/hexapeptide system improved healing, reduced erythema, exudation, tenderness, and burning/stinging, and increased subject satisfaction compared to a bland ointment and cream in 14 female subjects following facial laser resurfacing. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28371204/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25844613/))
- A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells. ([Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/25898765/))
- Topical formulations containing 1.25% Malus sp. extract or 0.75% rutin protected against UVB-induced sunburn cells, caspase-3 activation, cyclobutane pyrimidine dimers, lipid peroxidation, and metalloproteinase formation in ex vivo skin explants and 3D tissue-engineered skin. ([Rejuvenation Research, 2020](https://pubmed.ncbi.nlm.nih.gov/32242497/))

## What reviewers say

Users report this lightweight gel booster provides immediate plumping and hydration, often improving skin texture and softening fine lines overnight. While it is highly effective for firming and layering, a moderate number of users found the scent and price to be drawbacks, and a low number experienced breakouts or redness.

- Liked: Plumps and firms (mostly mentioned)
- Liked: Hydrates and glows (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: Expensive for size (often mentioned)
- Liked: Smooths lines (sometimes noted)
- Disliked: Messy packaging (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Caused breakouts (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Paula's Choice Pro-Collagen Multi-Peptide Booster a great fit for sensitive skin?

This booster is a great fit because it uses glycerin and sodium hyaluronate to keep your skin hydrated while palmitoyl tripeptide-5 helps firm and plump it. The formula also helps calm redness and irritation using soothing ingredients like polygonum bistorta root extract. It has a high safety profile and is unlikely to cause irritation on sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Which ingredients make this booster a good fit for sensitive skin?

This booster is a great fit because it contains Palmitoyl Tripeptide-5 and Polygonum Bistorta Root Extract to calm redness and reduce irritation. It is also very safe for sensitive skin because it is free of harsh ingredients that could trigger discomfort.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/), [International Journal of Cosmetic Science, 2019](https://pubmed.ncbi.nlm.nih.gov/31050807/)

### What does Peptide Complex do for sensitive skin?

Peptide complex helps improve hydration and smooths the look of fine lines for sensitive skin without causing irritation. It supports a healthy moisture barrier so skin stays soft and comfortable over time.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335808/), [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/41924746/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this booster go in a skincare routine for sensitive skin?

This booster goes in the evening routine after your toner and before your moisturizer. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this booster with retinol, and in what order?

You can use this booster with retinol by applying it after your retinol and before your moisturizer to keep your skin calm and hydrated. The formula is safe for sensitive skin and is unlikely to cause irritation.

### How often should I use this booster?

You can use this booster in your evening routine, applying it after your cleansing and toning steps and before your moisturizer. It is safe for sensitive skin and is unlikely to cause irritation because it contains no harsh ingredients.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this booster clog pores, cause breakouts or purging for sensitive skin?

Paula's Choice Pro-Collagen Multi-Peptide Booster is unlikely to clog pores or cause breakouts, as reviewers report a very low likelihood of this issue. Its gentle formula contains no harsh ingredients that typically upset sensitive skin, keeping your face calm and clear.

### Is this booster fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/sensitive-skin) — Average fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Pentylene Glycol, Hydrolyzed Yeast Extract, Pyrus Malus Fruit Extract, Dimethicone, Propanediol, 1,2-Hexanediol, Glyceryl Glucoside, Palmitoyl Tripeptide-72 Amide, Sh-Polypeptide-121, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tridecapeptide-1, Polyglucuronic Acid, Sodium Hyaluronate, C9-12 Alkane, Ammonium Polyacryloyldimethyl Taurate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Polygonum Bistorta Root Extract, Bacillus Ferment, Lecithin, Sodium Phytate, Coco-Caprylate Caprate, Hexylene Glycol, Cetyl Hydroxyethylcellulose, Xanthan Gum, Ethylhexylglycerin, Caprylyl Glycol, Magnesium Chloride, Potassium Sorbate, Sodium Benzoate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/sensitive-skin