# Obagi Professional-C Serum 20% for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Obagi](https://lovi.care/skincare/sg/brands/obagi)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate brightening for your normal skin due to Ascorbic Acid and Ascorbyl Glucoside, which provide antioxidant benefits and support collagen production.
- While the formula offers general hydration and cleansing, these benefits are mostly supportive and not directly targeted at your redness and irritation.
- The product is safe for your sensitive skin as it lacks harsh or prohibited ingredients, minimizing irritation risks.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Sodium Hyaluronate, Ascorbyl Glucoside, Zinc Chloride, Propylene Glycol

## What the research says

- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Treatment with ascorbyl glucoside-arginine complex lotion significantly decreased pigmentation scores and melanin index while increasing lightness in solar lentigos of Japanese females compared to placebo over 24 weeks. ([International Journal of Molecular Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/39769217/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- An aloe-alginate film dressing showed no statistical difference in wound contraction but demonstrated anti-inflammatory activity, stimulated angiogenesis, and increased collagen type I fibers while decreasing type III fibers compared to sterile gauze in rats with incisional skin wounds. ([Acta Cirurgica Brasileira, 2020](https://pubmed.ncbi.nlm.nih.gov/32638846/))
- Treatment with a combination of propylene glycol, ethanol, water, and shampoo was found effective, easy to use, and cosmetically attractive with no observed side effects in patients with dandruff. ([Cutis, 1988](https://pubmed.ncbi.nlm.nih.gov/2970946/))
- A moisturizer containing glycerol and propylene glycol reduced transepidermal water loss, decreased epidermal thickness, increased stratum corneum thickness, and reduced dermal inflammatory infiltrate compared to untreated disrupted skin in six healthy beagle dogs. ([Veterinary Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32628309/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Based on a very large amount of data, users with normal to oily skin report this high-potency serum provides a significant glow and brightens the complexion while improving skin texture. Many reviewers praise its effectiveness in fading hyperpigmentation, acne scars, and sun spots. Some users note it can be drying or irritating for sensitive skin types.

- Liked: Brightens complexion (mostly mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Absorbs quickly (sometimes noted)
- Liked: Smoothes skin texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Oxidizes quickly (sometimes noted)
- Liked: Reduces fine lines (rarely noted)
- Disliked: Causes dryness/irritation (rarely noted)
- Disliked: Poor packaging (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Obagi Professional-C Serum 20% work for sensitive skin?

Obagi Professional-C Serum 20% works moderately well for sensitive skin, as it is safe and provides brightening and hydration, though it does not directly target redness and irritation. A treatment for sensitive skin needs ingredients like niacinamide or soothing plant extracts that directly calm redness and irritation while keeping the skin soft and comfortable.
Sources: [Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/)

### Which ingredients make this serum a good fit for sensitive skin?

Ascorbic Acid and Ascorbyl Glucoside make this serum a fit by offering antioxidant benefits that support brightening, while Sodium Hyaluronate provides hydration. Though it is safe and minimizes irritation risks, it lacks ingredients that directly target redness. Sensitive skin of this type needs products with ingredients like niacinamide and snail secretion filtrate to properly calm redness and irritation.
Sources: [Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/)

### What does Vitamin C do for sensitive skin?

Vitamin C helps brighten skin, smooth out fine lines, and fade dark spots. Clinical studies show it is generally safe and well-tolerated when improving overall skin quality.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after cleansing and a soothing toner, followed by a moisturizer. A product for sensitive skin of this type needs calming ingredients and extra hydration to directly target redness and irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum in your morning routine and the retinol in your evening routine to help prevent irritation on sensitive skin. Using them at different times of day allows you to get the brightening benefits of vitamin C without overwhelming your skin with too many strong treatments at once.

### How often should I use this serum?

This treatment is used in the evening for simplicity and extra safety around sun exposure, though some treatments can also be used in the morning or twice a day. This product works for your sensitive skin, but since it does not target redness and irritation, sensitive skin needs a product that brings soothing and calming ingredients to keep skin calm and comfortable.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts or clog pores on sensitive skin because it lacks heavy, pore-clogging ingredients. However, it may occasionally cause mild dryness or irritation since it does not directly target redness.

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/sensitive-skin) — Average fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Propylene Glycol, Water, Ascorbic Acid, Alcohol, Ascorbyl Glucoside, Ethoxydiglycol, Phenoxyethanol, Sorbitol, Sodium Hyaluronate, Zinc Chloride, Calcium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/obagi/professional-c-serum-20/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/obagi/professional-c-serum-20/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/obagi/professional-c-serum-20/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/obagi/professional-c-serum-20/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/obagi/professional-c-serum-20/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/obagi/professional-c-serum-20/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/obagi/professional-c-serum-20/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/obagi/professional-c-serum-20/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/obagi/professional-c-serum-20/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/obagi/professional-c-serum-20/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/obagi/professional-c-serum-20/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/obagi/professional-c-serum-20/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/obagi/professional-c-serum-20/for/sensitive-skin