# numbuz:n No.3 Skin Softening Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [numbuz:n](https://lovi.care/skincare/sg/brands/numbuz-n)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your combination skin, this serum leverages Bifida Lysate Ferment and Galactomyces Ferment Filtrate to effectively regulate oil production and repair your skin barrier, addressing your acne and breakouts.
- Niacinamide further supports barrier function and reduces inflammation, while ingredients like squalane and sodium hyaluronate provide essential hydration without clogging pores.
- The product is safe for your skin, featuring a gentle formula with soothing agents and no harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/oily-acne-prone-skin): High

## Key ingredients

Bifida Lysate Ferment, Galactomyces Ferment Filtrate, Niacinamide, Sodium Hyaluronate, Squalane

## What the research says

- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- Application of Galactomyces ferment filtrate skin care formula significantly reduced the net values and daily fluctuation of facial pore area, roughness, and redness in young Japanese women. ([Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/))
- Daily application of Galactomyces ferment filtrate-containing skin products for 12 months significantly and cumulatively reversed 11-year facial skin aging parameters of wrinkles, hyperpigmented spots, and roughness, and increased skin hydration in 86 female volunteers. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/36769815/))
- A combination serum containing galactomyces ferment filtrate, dexpanthenol, and Centella asiatica effectively treated post-acne hyperpigmentation in subjects with colored skin by significantly increasing lightness scores in Fitzpatrick skin type V and reducing the melanin index in Fitzpatrick skin type IV compared to placebo. ([Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/))
- Galactomyces ferment filtrate promotes epidermal interconnectivity, barrier development, cell adhesion, keratinocyte differentiation and proliferation, and protects cellular bioenergetics against stress in keratinocytes and ex vivo skin explants compared to untreated controls. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38924095/))
- Galactomyces ferment filtrate activates AHR and NRF2, upregulates filaggrin and terminal differentiation markers, exhibits antioxidative activity, promotes antiinflammatory IL-37, and downregulates CDKN2A, IL-33, CXCL14, and IL6R in epidermal keratinocytes. ([Journal of Clinical Medicine, 2022](https://pubmed.ncbi.nlm.nih.gov/36362566/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Based on a very large amount of data, this serum is highly effective at softening and smoothing skin, providing a radiant glow and deep hydration, with many users achieving a 'glass skin' appearance. However, a moderate number of users report breakouts and fungal acne flare-ups, while a low number experience irritation or find the finish sticky. This summary should be definitely taken into account.

- Liked: Softens skin (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Improves radiance (often mentioned)
- Liked: Elegant texture (sometimes noted)
- Disliked: Causes breakouts (sometimes noted)
- Disliked: Causes irritation (rarely noted)
- Disliked: No results (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes numbuz:n No.3 Skin Softening Serum a great fit for acne-prone skin?

This serum is a great fit for your acne-prone skin because it uses fermented ingredients to help regulate oil and repair your skin barrier. It also includes niacinamide to calm redness, along with squalane and sodium hyaluronate to deliver lightweight hydration that keeps your skin smooth without clogging pores.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit because Bifida Lysate Ferment and Galactomyces Ferment Filtrate regulate oil and repair the skin barrier to help clear breakouts. Niacinamide further calms redness, while squalane and sodium hyaluronate deliver lightweight hydration that is unlikely to clog pores.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/)

### What does Bifida Ferment Lysate do for acne-prone skin?

Bifida Ferment Lysate helps acne-prone skin by calming redness and keeping the skin barrier strong. This ingredient may also support the skin's defenses against irritation, making it less likely to flare up.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Galactomyces Ferment Filtrate do for acne-prone skin?

Galactomyces ferment filtrate helps keep acne-prone skin calm and smooth by reducing redness and evening out dark spots left behind by breakouts. It also helps manage daily changes in pore size so your skin stays clearer and more balanced.
Sources: [Skinmed, 2021](https://pubmed.ncbi.nlm.nih.gov/33938432/), [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to hydrate and calm your skin, followed by your retinol. This gentle formula helps reduce irritation while supporting your skin barrier during active treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this serum?

This serum is a great fit for your acne-prone skin and is designed to be used in the evening as part of your routine. Daily application helps keep your skin calm and balanced while providing essential hydration without clogging pores.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is a great fit for your acne-prone skin because it uses fermentation ingredients like Galactomyces and Bifida to balance oil and strengthen your skin barrier. While some reviewers mention breakouts, the formula is gentle and includes ingredients like squalane and sodium hyaluronate to hydrate without clogging pores.
Sources: [Journal of Clinical Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34198790/)

### Can I use this serum around the eyes or on my body?

This serum is safe to use on the thin skin around the eyes and on the body because its gentle formula provides essential hydration without clogging pores. The delicate eye area and body skin may benefit from its soothing agents and barrier-supporting ingredients.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/sg/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin) — High fit — S$41.73 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/sg/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/acne-prone-skin) — High fit — S$21.96 at YesStyle
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin) — Average fit — S$23.12 at YesStyle

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sg/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — S$36.14 at Amazon

## Where to buy

- Amazon.sg: S$36.60 (https://www.amazon.sg/dp/B0F63CBMYL?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Galactomyces Ferment Filtrate, Butylene Glycol, Methyl Gluceth-20, Water, Niacinamide, Peg-90, 1,2-Hexanediol, Glycerin, Squalane, Alteromonas Extract Ferment, Silk Extract, Goat Extract Milk, Sodium Hyaluronate, Panthenol, Adenosine, Glycereth-26, Xanthan Gum, Polyglyceryl-3 Distearate, Glyceryl Stearate Se, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Carbomer, Tromethamine, Ethylhexylglycerin, Caprylyl Glycol, Tropolone, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/numbuz-n/no-3-skin-softening-serum/for/acne-prone-skin