# NUE Barrier Clear Treatment for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [NUE](https://lovi.care/skincare/sg/brands/nue)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Suitable for normal skin, this treatment offers excellent barrier resilience due to live probiotic and ACB bio-chelate 5pf, which enhance barrier function and provide anti-inflammatory action. Mangifera Indica Leaf Extract offers general soothing benefits for redness and irritation, though specialized ingredients for sensitivity are not present.
- The formula is safe for your sensitive skin, as it lacks harsh ingredients and includes soothing Mangifera Indica Leaf Extract.
- The product is well-suited for normal skin types and addresses barrier resilience effectively.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/oily-acne-prone-skin): Average

## Key ingredients

Live Probiotic, Dendriclear

## What the research says

- Topical application of live Lactobacillus reuteri DSM 17938 and its lysate reduced proinflammatory IL-6 and IL-8 in UVB-R-induced inflammation models, with live bacteria also increasing aquaporin 3 expression and exhibiting antimicrobial activity against skin pathogens. ([Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/))
- Topical probiotics, synbiotics, and postbiotics promote antimicrobial and anti-inflammatory properties, angiogenesis, tissue regeneration, and skin barrier restoration in preclinical wound models compared to untreated or control conditions. ([Pharmaceuticals, 2025](https://pubmed.ncbi.nlm.nih.gov/40430523/))
- Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers. ([International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Laser-assisted delivery of vitamin C, vitamin E, and ferulic acid serum decreased postoperative edema and erythema and increased basic fibroblast growth factor expression in fifteen healthy adults compared to vehicle control. ([Lasers in Surgery and Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26612341/))

## What reviewers say

It is frequently highlighted as a gentle, effective solution for those with sensitive or breakout-prone skin who need barrier support alongside blemish control.

- Liked: Calms breakouts (often mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Non-greasy formula (sometimes noted)
- Liked: Strengthens barrier (sometimes noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does NUE Barrier Clear Treatment work for sensitive skin?

NUE Barrier Clear Treatment is an average fit for sensitive skin, as it is safe and includes soothing Mangifera Indica Leaf Extract, though it lacks specialized ingredients for sensitivity. To fit this skin better, a treatment of this type needs specialized soothing ingredients, potent antioxidants, hydrating components, and skin-repairing ingredients that calm redness and irritation without any risk of unsuitability.
Sources: [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/), [Pharmaceuticals, 2025](https://pubmed.ncbi.nlm.nih.gov/40430523/)

### Which ingredients make this treatment a good fit for sensitive skin?

This treatment is a safe fit for sensitive skin because it avoids harsh ingredients and includes soothing Mangifera Indica Leaf Extract. To work even better for sensitive skin, a product of this type needs specialized soothing ingredients, antioxidants, and hydrating components that reduce redness and irritation without causing adverse effects.
Sources: [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/), [Pharmaceuticals, 2025](https://pubmed.ncbi.nlm.nih.gov/40430523/)

### What does Live Probiotic do for sensitive skin?

Live probiotic helps calm sensitive skin by reducing irritation and boosting moisture so your face feels smooth and comfortable. It is unlikely to cause irritation and has a very safe profile for daily use.
Sources: [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38186043/)

### What does Dendriclear do for sensitive skin?

Dendriclear helps calm and balance oily or breakout-prone skin by targeting the root causes of blemishes to keep your complexion clear and smooth. Because sensitive skin can easily react to harsh blemish treatments, this ingredient is designed with a gentle profile that is unlikely to cause irritation.

### Where does it go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. It is safe for sensitive skin because it avoids harsh ingredients and includes soothing mango leaf extract, though a treatment for this skin needs specialized ingredients to fully calm redness and irritation.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol, but since it lacks specialized ingredients for sensitive skin, this skin needs a product that includes calming agents like centella asiatica or thermal spring water to keep things comfortable.

### How often should I use it?

Apply this treatment in the evening, using it during your PM routine as suggested by the routine guide. Sensitive skin needs products with specialized calming and soothing ingredients designed to target redness and irritation effectively.
Sources: [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/), [Pharmaceuticals, 2025](https://pubmed.ncbi.nlm.nih.gov/40430523/)

### Can this treatment clog pores, cause breakouts or purging for sensitive skin?

This treatment is unlikely to clog pores or cause breakouts for sensitive skin, as it lacks harsh ingredients and includes soothing Mangifera Indica Leaf Extract. To properly care for sensitive skin, a product of this type needs specialized calming ingredients and barrier-strengthening components that reduce redness and irritation.

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/sensitive-skin) — Average fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Live Probiotic, Dendriclear, Acb Bio-Chelate 5pf, Mangifera Indica Leaf Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/nue/barrier-clear-treatment/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/nue/barrier-clear-treatment/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/nue/barrier-clear-treatment/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/nue/barrier-clear-treatment/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/nue/barrier-clear-treatment/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/nue/barrier-clear-treatment/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/nue/barrier-clear-treatment/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/nue/barrier-clear-treatment/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/nue/barrier-clear-treatment/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/nue/barrier-clear-treatment/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/nue/barrier-clear-treatment/for/sensitive-skin