# NINELESS A-Control 10% Azelaic Acid Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [NINELESS](https://lovi.care/skincare/sg/brands/nineless)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for combination skin.

## Why this fit

- Highly suitable for your combination skin, the azelaic acid and niacinamide effectively target oily shine and reduce pore appearance by controlling sebum production and offering anti-inflammatory benefits.
- Snail mucin further supports skin hydration and repair, complementing the primary actives for overall skin health.
- The formula is safe for your skin, with no risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Niacinamide, Snail Mucin

## What the research says

- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))
- Cruelty-free extracted snail slime promotes fibroblast viability, triggers recovery through Erk protein activation, reduces cyclooxygenase-2 expression, and increases angiopoietin 1 gene expression and collagen I release in skin cell populations. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/36770889/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- HelixComplex snail mucus protected human keratinocytes and reconstructed human epidermis models from ozone-induced oxidative damage and pro-inflammatory response following exposure to 0.5 ppm ozone for 2 hours. ([PloS One, 2020](https://pubmed.ncbi.nlm.nih.gov/32084249/))
- Topical treatment with Snail Secretion Filtrate significantly improves the speed and percentage of wound area closure, enhances proliferation and tissue remodeling, and reduces inflammation in a full-thickness excisional wound model in mice compared to untreated controls. ([Veterinary Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34437489/))
- Topical application of 48% and 96% snail mucus increases angiogenesis during wound healing in Wistar rat skin compared to lower concentrations and control. ([F1000Research, 2021](https://pubmed.ncbi.nlm.nih.gov/38912381/))

## What reviewers say

Users with acne-prone and sensitive skin highly praise this serum for its ability to calm redness and soothe inflammation without causing irritation. While the lightweight, watery texture is frequently complimented for layering well, many users note that fading hyperpigmentation (PIE/PIH) is a gradual process requiring consistent long-term use.

- Liked: Calms redness (mostly mentioned)
- Liked: Lightweight texture (mostly mentioned)
- Liked: Controls acne (often mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Hydrating effect (sometimes noted)
- Disliked: Slow on pigmentation (sometimes noted)
- Disliked: Dropper issues (rarely noted)
- Disliked: Initial purging (rarely noted)
- Disliked: Slight tackiness (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes NINELESS Azelaic Acid Serum a great fit for combination skin?

This serum is a great fit because azelaic acid and niacinamide help control oily shine and reduce pore size while calming the skin. Snail mucin further supports hydration and repair, keeping the skin balanced and healthy.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/)

### Which ingredients make this serum a good fit for combination skin?

Azelaic acid and niacinamide make this serum a great fit for combination skin because they control oily shine and reduce pore appearance, while snail mucin supports hydration and repair.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/36770889/)

### What does Azelaic Acid do for combination skin?

Azelaic acid helps combination skin by calming redness, clearing breakouts, and fading dark spots while keeping the skin smooth. It is unlikely to irritate dry areas while working on oily spots. Combination skin of this type needs a balanced routine with gentle exfoliants and soothing hydrators.
Sources: [Postepy Dermatologii I Alergologii, 2023](https://pubmed.ncbi.nlm.nih.gov/38282869/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26355614/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and before moisturizing. The formula helps control oily shine and calm the skin while supporting hydration, and it is unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36798538/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and then following with your retinol on separate nights or spaced out carefully to avoid irritation. Because both ingredients are active, alternating their use or introducing them slowly helps your skin adjust comfortably.

### How often should I use this serum?

This treatment is great for your combination skin and is used in the evening routine. It is a safe and gentle fit that helps control oily shine and large pores while keeping your skin calm.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores and carries only a low likelihood of causing initial breakouts for combination skin. Its soothing ingredients help control excess oil and calm inflammation while supporting your skin gently.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/36770889/)

## Alternatives for combination skin

- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/combination-skin) — High fit — S$28.55 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/combination-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [Whamisa Organic Flowers Toner Deep Rich](https://lovi.care/skincare/sg/p/whamisa/organic-flowers-toner-deep-rich/for/combination-skin) — Superior fit — S$64.81 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/sg/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — S$28.72 at Amazon

## Where to buy

- YesStyle: S$9.31 (https://www.yesstyle.com/en/nineless-a-control-10-azelaic-acid-serum-30ml/info.html/pid.1137753389?curr=SGD&rco=SG)
Prices checked 13 Oct 2026.

## Ingredients

Azelaic Acid, Niacinamide, Snail Mucin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/nineless/a-control-10-azelaic-acid-serum/for/combination-skin