NEOGEN DERMALOGY Probiotics Youth Repair Cream for acne-prone skin

How to apply

Questions and answers

What the research says

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine.

  Journal of Pharmacy & Pharmaceutical Sciences, 2015

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality.

  Archives of Facial Plastic Surgery, 2006

• A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days.

  Cureus, 2024

• The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls.

  Skin Research and Technology, 2026

• Applying an essence containing royal jelly extract significantly increased the stratum corneum water content of the cheeks compared to placebo in healthy Japanese adults over 4 weeks.

  Journal of Cosmetic Dermatology, 2022

• A prototype body cream containing bee venom, propolis, honey, beeswax, and royal jelly demonstrated stability for 90 days, high antioxidant capacity of 85.45%, lack of cytotoxicity with over 70% cell viability, and no irritation or allergic reaction in dermatological analysis, while improving skin parameters in a panel test.

  Journal of Cosmetic Dermatology, 2022

• Royal jelly protects against epidermal stress caused by UVB and menadione through the upregulation of NQO1 expression by its active compound 10-hydroxy-2-decenoic acid.

  International Journal of Molecular Sciences, 2021

Why other moisturizers fit acne-prone skin better

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

Ingredients

Water, Butylene Glycol, Caprylic Capric Triglyceride, Glycerin, Trehalose, Cyclopentasiloxane, Glyceryl Stearate, 1,2-Hexanediol, Niacinamide, Octyldodecyl Myristate, Peg-100 Stearate, Cyclohexasiloxane, Hydrogenated C6-14 Olefin Polymers, Dimethicone, Phytosteryl Behenyl Octyldodecyl Lauroyl Glutamate, Butyrospermum Parkii Butter Shea Butter, Palmitic Acid, Hydrogenated Olive Lauryl Esters Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Stearic Acid, Cetyl Peg Ppg-10 1 Dimethicone, Polyacrylamide, Cetyl Alcohol, Stearyl Alcohol, Tocopheryl Acetate, C13-14 Isoparaffin, Dimethiconol, Beeswax, Ethylhexylglycerin, Laureth-7, Microcrystalline Wax, Adenosine, Sodium Hyaluronate, Coptis Japonica Extract, Lactobacillus Lysate Ferment, Isopentyldiol, Dextrin, Theobroma Cacao Extract, Tocopherol, Betaine, Allantoin, Xylitol, Panthenol, Hydrolyzed Collagen, Juglans Regia Seed Oil, Squalane, Lactic Acid, Undaria Pinnatifida Extract, Polydecene, Propanediol, Honey Extract, Sodium Pca, Sodium Lactate, Arginine, Olea Europaea Oil Fruit Olive Oil Fruit, Bifida Lysate Ferment, Aspartic Acid, Adansonia Digitata Seed Oil, Hibiscus Sabdariffa Flower Extract, Pca, Ceramide Np, Hydrogenated Lecithin, Acacia Senegal Gum, Agar, Gluconic Acid, Streptococcus Thermophilus Ferment, Xanthan Gum, Glycine, Alanine, Royal Jelly Extract, Musa Sapientum Fruit Extract, Tuber Melanosporum Extract, Propolis Extract, Daucus Carota Sativa Root Extract Carrot Root Extract, Artemisia Capillaris Extract, Serine, Valine, Guaiazulene, Caprylyl Glycol, Cholesterol, Isoleucine, Threonine, Proline, Tuber Magnatum Extract, Phenylalanine, Histidine, Phellinus Linteus Extract, Glutathione, Ceramide Ns, Ceramide, Ceramide Eop, Ceramide Ap, Glucose, Beta-Glucan, Chondrus Crispus Extract, Panax Ginseng Extract Berry, Phytosterols, Hydroxypropyltrimonium Hyaluronate, Crocus Sativus Flower Extract, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Copper Tripeptide-1, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Acetyl Hexapeptide-8, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Hexapeptide-9, Tripeptide-2, Nonapeptide-1, Hexapeptide-11, Potassium Hyaluronate, Disodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.