# Mixa Urea Cica Repair for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Mixa](https://lovi.care/skincare/sg/brands/mixa)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin as urea and hyaluronic acid provide excellent humectant action and support barrier repair, offering moderate benefits for your wrinkles and fine lines.
- Panthenol and allantoin further enhance skin hydration and soothe the skin, contributing to a smoother appearance.
- The product is safe for your skin due to the absence of prohibited or harsh ingredients, posing no risks of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/oily-acne-prone-skin): Average

## Key ingredients

Urea, Niacinamide, Hyaluronic Acid, Panthenol, Allantoin

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical 40% urea cream achieved improvement in less time and showed superiority over 12% ammonium lactate lotion in skin roughness, fissure reduction, thickness, and dryness at day 14 in patients treated for moderate to severe xerosis. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/11978141/))
- Topical treatment with K101 achieved a significantly higher mycological cure rate compared to placebo in patients with ≤50% nail involvement (27.2% vs 10.4%), while showing early visible improvements in nail appearance and no safety issues. ([Mycoses, 2012](https://pubmed.ncbi.nlm.nih.gov/22681227/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Mixa Urea Cica Repair a great fit for mature skin?

Mixa Urea Cica Repair is a great fit for mature skin because urea and hyaluronic acid deeply hydrate and strengthen the skin barrier while helping smooth out wrinkles and fine lines. Panthenol and allantoin add even more moisture to keep your skin calm and give it a noticeably softer, smoother look.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for mature skin?

Urea and hyaluronic acid make this cream a great fit for mature skin by drawing in moisture and helping repair the skin barrier. Panthenol and allantoin further boost hydration and calm the skin, which helps smooth out the look of fine lines and wrinkles.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Urea do for mature skin?

Urea helps deeply hydrate dry and mature skin while improving the skin barrier and reducing flaking. It is generally safe and well tolerated, though higher strengths may occasionally cause mild smarting on very sensitive areas.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34596890/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does it go in a skincare routine for mature skin?

This moisturizing treatment goes in the evening routine after cleansing and before your usual moisturizer. Using a daily moisturizer helps keep mature skin soft and hydrated while supporting barrier repair.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this cream alongside retinol by applying the retinol first and following it with this moisturizer to help soothe the skin and lock in moisture. This combination is generally safe and helps keep mature skin soft while reducing dryness.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use it?

You can use this moisturizing treatment twice a day to help keep your mature skin soft and hydrated. Regular daily application supports your skin barrier and may improve the look of fine lines and wrinkles over time.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41231732/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

Mixa Urea Cica Repair is unlikely to clog pores, cause breakouts, or trigger purging on mature skin because it has a safe formula without harsh ingredients that cause irritation.

### Can I use it around the eyes or on my body?

You can use this moisturizing treatment safely both on your body and around your eyes, as it is very well tolerated by the skin. Its ingredients help keep the skin hydrated and smooth while posing virtually no risk of irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/sg/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — S$103.92 at Amazon
- [Sulwhasoo Ginseng Renewing Cream Ex](https://lovi.care/skincare/sg/p/sulwhasoo/ginseng-renewing-cream-ex/for/mature-skin) — Superior fit — S$73.41 at Amazon
- [NEOGEN DERMALOGY Probiotics Youth Repair Cream](https://lovi.care/skincare/sg/p/neogen-dermalogy/probiotics-youth-repair-cream/for/mature-skin) — Superior fit — S$47.90 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Urea, Cetearyl Alcohol, Butyrospermum Parkii Butter Shea Butter, Caprylic Capric Triglyceride, Cetearyl Glucoside, Dimethicone, Panthenol, Allantoin, Hyaluronic Acid, Tocopherol, Phenoxyethanol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mixa/urea-cica-repair/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mixa/urea-cica-repair/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/mixa/urea-cica-repair/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/mixa/urea-cica-repair/for/mature-skin
- France: https://lovi.care/skincare/fr/p/mixa/urea-cica-repair/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/mixa/urea-cica-repair/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/mixa/urea-cica-repair/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/mixa/urea-cica-repair/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/mixa/urea-cica-repair/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/mixa/urea-cica-repair/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/mixa/urea-cica-repair/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/mixa/urea-cica-repair/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mixa/urea-cica-repair/for/mature-skin