# Medik8 Sleep Glycolic for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Medik8](https://lovi.care/skincare/sg/brands/medik8)
Category: [Exfoliants](https://lovi.care/skincare/sg/best/exfoliators)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other products fit it better.

## Why this fit

- Offers moderate exfoliation for your combination skin, as glycolic acid helps to resurface the skin and address acne and blemishes by providing keratolytic action.
- Glycerin is included to provide humectant action, supporting skin hydration for combination skin.
- The product is generally safe for your skin, with a low risk of irritation from glycolic acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/oily-acne-prone-skin): Average

## Key ingredients

Glycolic Acid, Glycerin, Lespedeza Capitata Stem Extract Flower Leaf, Dimethicone, Cyclodextrin

## What the research says

- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- A combination of dermapen and glycolic acid peel significantly decreased acne scar grades and resulted in higher patient satisfaction compared to either monotherapy in 30 patients. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30548170/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- The circadian clock component PER represses MMP-1 expression via the cAMP signaling pathway and mediates the MMP-1 suppression induced by Lespedeza capitata extract in HaCaT keratinocytes. ([Molecules, 2018](https://pubmed.ncbi.nlm.nih.gov/29570674/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Topical retinoic acid-beta-cyclodextrin complex formulations at 0.025% showed greater acne improvement scores (4.0-4.1) and lower irritation than a commercial 0.05% retinoic acid gel (score 3, with side effects in all patients) after 3 months in 66 patients with acne vulgaris. ([Journal of the European Academy of Dermatology and Venereology, 2004](https://pubmed.ncbi.nlm.nih.gov/15196153/))
- Tretinoin cyclodextrin complex demonstrated an antiwrinkle effect equal to that of conventional tretinoin with more moderate irritant reactions in photoaged patients. ([Aesthetic Plastic Surgery, 2012](https://pubmed.ncbi.nlm.nih.gov/22538278/))
- Binary systems of trans-resveratrol with polyethylene glycol or beta-cyclodextrin enhanced its antioxidant activity and in vivo skin anti-aging effects compared to trans-resveratrol alone in human keratinocytes and volunteers. ([Drug Development and Industrial Pharmacy, 2014](https://pubmed.ncbi.nlm.nih.gov/23862976/))

## What reviewers say

Based on a very large amount of data, this product is highly praised for its ability to transform dull skin into a glowing, radiant complexion. Users report significant improvements in skin texture, hyperpigmentation, and fine lines, with many noting a lack of irritation. Some users experience a mild tingling sensation or dryness.

- Liked: Glowing, radiant skin (mostly mentioned)
- Liked: Smoother skin texture (mostly mentioned)
- Liked: No irritation (often mentioned)
- Liked: Reduces dullness (sometimes noted)
- Disliked: Causes mild dryness (rarely noted)
- Disliked: Slight tingling sensation (rarely noted)
- Disliked: Too strong frequently (rarely noted)

## How to apply

- Use this exfoliant PM once a week to start, and gradually increase if your combination skin tolerates it well. Always apply SPF the next morning to protect your clear skin.
- Apply the exfoliant after cleansing and toning, but right before your moisturizer step. This ensures the treatment targets blemishes effectively.
- Gently press 2-3 drops of the exfoliant into your skin without rubbing. Let it absorb for a minute before moving to the next step.
- Apply the exfoliant on clean, dry skin to help control breakouts safely. Since your skin is not sensitive, this dry application method ensures good product absorption.
- Avoid the sensitive eye area and do a patch test before your first use. Do not mix this exfoliant with other strong acids in the same routine.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### How well does Medik8 Sleep Glycolic work for acne-prone skin?

Medik8 Sleep Glycolic works moderately well for acne-prone skin, as it helps resurface the skin and address blemishes with a low risk of irritation. To fit this skin type best, an exfoliant treatment needs effective ingredients like niacinamide, propolis, or zinc PCA that target breakouts and control oiliness while keeping the skin balanced and hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this exfoliant a good fit for acne-prone skin?

Glycolic acid helps resurface your acne-prone skin and address blemishes by clearing away dead cells, while glycerin supports skin hydration. To work best for this skin type, a product of this type needs calming and balancing ingredients like niacinamide, propolis, or zinc PCA that target breakouts while keeping hydration balanced without extra oiliness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycolic Acid do for acne-prone skin?

Glycolic acid helps clear acne-prone skin by reducing pimples and breakouts. It also helps fade dark spots left behind by acne and controls skin oiliness, with very few side effects when used properly.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33617668/), [Dermatologic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24447110/)

### What does Glycerin do for acne-prone skin?

Glycerin helps keep acne-prone skin hydrated and calm without clogging pores or feeling heavy. It supports the skin barrier so it stays soft and smooth while handling everyday treatments.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [International Journal of Toxicology, 2019](https://pubmed.ncbi.nlm.nih.gov/31840548/)

### Where does this exfoliant go in a skincare routine for acne-prone skin?

This exfoliant goes in the evening routine after cleansing, because treatments with active ingredients are best used at night for simplicity and safety around sun exposure. This product works for your skin, though other products fit it better, so an acne-prone skin type needs a product that offers gentle exfoliation with soothing and hydrating ingredients to clear blemishes while keeping skin calm and comfortable.

### Can I use it with retinol, and in what order?

Using this treatment with retinol on acne-prone skin may easily lead to irritation, so it is best to use them on alternate nights rather than together. When combining potent actives like these, incorporating soothing ingredients and reliable moisturizers helps keep the skin calm and hydrated.

### How often should I use it?

Start by using it once a week in the evening, and if your skin feels comfortable and you see good results, you can carefully use it more often. This type of skin needs gentle exfoliating ingredients paired with hydrating ingredients to keep the skin calm and clear.

### Can this exfoliant clog pores, cause breakouts or purging for acne-prone skin?

Medik8 Sleep Glycolic is unlikely to clog pores or cause breakouts on acne-prone skin, and may help resurface the skin to address blemishes with a low risk of irritation. Because this product is an average fit, acne-prone skin needs products containing ingredients like salicylic acid and soothing agents to better target breakouts without extra dryness.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [Clean & Clear Persa-Gel 10 Acne Medication](https://lovi.care/skincare/sg/p/clean-and-clear/persa-gel-10/for/acne-prone-skin) — Superior fit — S$25.46 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — S$28.55 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycolic Acid, Cyclodextrin, Caprylic Capric Triglyceride, Dimethicone, Glyceryl Stearate, Sucrose Stearate, Sodium Hydroxide, Glycerin, Phenoxyethanol, Lespedeza Capitata Stem Extract Flower Leaf, Propanediol, Xanthan Gum, Ethylhexylglycerin, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Sorbitan Isostearate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medik8/sleep-glycolic/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medik8/sleep-glycolic/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medik8/sleep-glycolic/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medik8/sleep-glycolic/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medik8/sleep-glycolic/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medik8/sleep-glycolic/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medik8/sleep-glycolic/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medik8/sleep-glycolic/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medik8/sleep-glycolic/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medik8/sleep-glycolic/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medik8/sleep-glycolic/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/medik8/sleep-glycolic/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medik8/sleep-glycolic/for/acne-prone-skin