# MEDIHEAL AGE-R for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/mediheal/age-r/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [MEDIHEAL](https://lovi.care/skincare/sg/brands/mediheal)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate plumping and firming for your normal skin due to collagen and peptides, which also provide soothing effects for redness and irritation.
- The presence of glutathione further supports general skincare benefits, enhancing overall skin health.
- The product is safe for your sensitive skin as it lacks harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/oily-skin): Caution
- [Dry skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/sg/p/mediheal/age-r/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/mediheal/age-r/for/oily-acne-prone-skin): Caution

## Key ingredients

Glutathione, Collagen, Peptides

## What the research says

- Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen. ([Dermatology Practical & Conceptual, 2022](https://pubmed.ncbi.nlm.nih.gov/35223163/))
- The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage. ([Current Issues in Molecular Biology, 2024](https://pubmed.ncbi.nlm.nih.gov/38534748/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Glutathione at 500 mg/day orally or 2.0% topically may brighten skin color in sun-exposed areas measured by melanin index, though current evidence remains inconclusive. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30895708/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- RayGel reduced skin reaction severity with a lower average score of 93.7 compared to 123.3 for the placebo group in patients undergoing whole breast external-beam irradiation. ([American Journal of Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/15862509/))
- Combining high-intensity focused ultrasound with a topical agent containing glutathione and hyaluronic acid significantly improves skin quality, fine wrinkles, hyperpigmentation, hydration, and brightness in female volunteers compared to the topical agent alone. ([The Journal of Dermatological Treatment, 2024](https://pubmed.ncbi.nlm.nih.gov/39326871/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))

## What reviewers say

Based on a very large amount of data, users frequently achieve a 'glass skin' appearance and improved facial contouring, with many reporting enhanced product absorption and a more radiant complexion. While effective for dullness and mild sagging, results are highly dependent on consistent daily use, which some users find difficult to maintain. The device is also noted for improving skin texture and reducing pore visibility.

- Liked: Enhanced absorption (mostly mentioned)
- Liked: Glass skin glow (often mentioned)
- Disliked: Time-consuming routine (often mentioned)
- Liked: Improved texture (sometimes noted)
- Liked: Visible lifting (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Unpleasant sensation (sometimes noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Mediheal AGE-R work for sensitive skin?

Mediheal AGE-R works for sensitive skin, though other treatments fit it better by being exceptionally well-suited and highly compatible. A treatment for this skin needs effective ingredients that calm redness and irritation, provide deep hydration, and protect against irritation while supporting overall skin health.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### Which ingredients make this cream a good fit for sensitive skin?

Glutathione, collagen, and peptides help make this treatment a safe and moderate fit for your sensitive skin by offering soothing effects for redness and irritation while avoiding harsh ingredients. A treatment that fits this skin type even better needs powerful soothing ingredients, deep hydration, and helpful antioxidants like niacinamide or snail secretion filtrate to calm redness safely.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### What does Glutathione do for sensitive skin?

Glutathione helps calm sensitive skin by reducing oxidative stress and protecting against environmental irritation. It is unlikely to cause irritation and has a very safe profile when used on the skin.
Sources: [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/), [Indian Journal of Dermatology, Venereology and Leprology, 2016](https://pubmed.ncbi.nlm.nih.gov/27088927/)

### What does Collagen do for sensitive skin?

Collagen helps soothe sensitive skin by reducing dryness, redness, and rough patches while keeping moisture locked in. It improves the skin barrier so it is less easily irritated, and studies show it is well tolerated and safe for sensitive skin types.
Sources: [International Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19496838/), [Pharmaceutical Development and Technology, 2014](https://pubmed.ncbi.nlm.nih.gov/23675949/)

### Where does this cream go in a skincare routine for sensitive skin?

This treatment goes in your evening routine, applied after your cleanser and soothing toner and before your moisturizer. It is safe for your sensitive skin because it lacks harsh ingredients, though a product of this type for your skin needs soothing ingredients and gentle hydrators to keep redness calm and soft.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol in your evening routine, but this product may only be an average fit for your sensitive skin. To truly feel comfortable and smooth while using both, this skin needs gentle, fragrance-free hydrating ingredients and soothing plant extracts that calm redness without harsh actives.

### How often should I use this cream?

You can use this treatment in the evening as part of your routine. Sensitive skin needs a product of this type that features gentle soothing ingredients and lacks harsh components to keep redness calm and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/), [Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/)

### Can it clog pores, cause breakouts or purging for sensitive skin?

This treatment is unlikely to clog pores or cause breakouts on sensitive skin as it lacks harsh or prohibited ingredients. However, it may cause mild irritation for some users since a few reviewers report an unpleasant sensation.

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/sensitive-skin) — Average fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Glutathione, Collagen, Peptides
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/age-r/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/age-r/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/age-r/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/age-r/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/mediheal/age-r/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/age-r/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/age-r/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/age-r/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/age-r/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/age-r/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/age-r/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/age-r/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/age-r/for/sensitive-skin