# Medicube Zero Pore Serum 2.0 for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Medicube](https://lovi.care/skincare/sg/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for dry skin as butylene glycol and cetyl ethylhexanoate provide some hydration, though it lacks sufficient occlusive ingredients for optimal moisture retention on dry or flaky skin.
- The presence of fomes officinalis extract and cinnamomum zeylanicum bark extract offers moderate pore-minimizing effects, which is a supportive benefit for your skin.
- The product is safe for your dry and sensitive skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/oily-acne-prone-skin): Caution

## Key ingredients

Dimethicone, Mentha Rotundifolia Leaf Extract, Citrus Aurantifolia Peel Extract, Fomes Officinalis Extract Mushroom Extract

## What the research says

- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Aqueous extracts of apple mint leaves inhibited heat shock-induced production of reactive oxygen species, matrix metalloproteinases, interleukin-8, and mitogen-activated protein kinases in human dermal fibroblasts. ([Evidence-based Complementary and Alternative Medicine, 2018](https://pubmed.ncbi.nlm.nih.gov/30254686/))
- White button mushroom extract treatment increased VEGF densities, EGF, PCNA, and collagen fibers, while decreasing apoptotic cells and limiting TGF-beta and CD4 reactions in ICR mice and chorioallantoic culture, indicating beneficial effects on skin regeneration and injury. ([Microscopy Research and Technique, 2012](https://pubmed.ncbi.nlm.nih.gov/22581761/))

## Why other serums fit dry sensitive skin better

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A formulation containing glycerol (5%) and xylitol (5%) applied twice daily for 14 days increased skin hydration, filaggrin protein quantity, interdigitation index, and biomechanical properties, and decreased transepidermal water loss compared to untreated and vehicle-treated skin in twelve volunteers with dry skin. ([Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/))
- Colloidal oatmeal induced skin barrier-related gene expression in vitro and showed significant clinical improvements in skin dryness, moisturization, and barrier in 50 healthy female subjects treated with a colloidal oatmeal lotion. ([Journal of Drugs in Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27272074/))

## What reviewers say

Users with oily and combination skin frequently report that this serum effectively regulates sebum and improves overall skin texture, creating a smoother base for makeup. While many users noticed a visible tightening of pores and a "glass skin" effect, results regarding actual pore size reduction are mixed, with some finding it highly effective and others seeing no significant change.

- Liked: Smoother skin texture (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Oil & sebum control (often mentioned)
- Disliked: Sticky texture (often mentioned)
- Liked: Pore tightening (sometimes noted)
- Disliked: Ineffective for some (sometimes noted)
- Disliked: Unpleasant fragrance (sometimes noted)
- Disliked: Price vs. quantity (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Medicube Zero Pore Serum 2.0 work for dry sensitive skin?

Medicube Zero Pore Serum 2.0 works moderately well for dry sensitive skin by providing some hydration and pore-minimizing benefits without causing irritation. However, it lacks enough heavy sealing ingredients to lock in moisture, meaning dry skin of this type needs richer nourishing agents and protective barriers to stay fully soft and smooth.
Sources: [Journal of Controlled Release, 2022](https://pubmed.ncbi.nlm.nih.gov/35150813/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Butylene glycol and cetyl ethylhexanoate help by providing some hydration, while fomes officinalis extract and cinnamomum zeylanicum bark extract offer moderate pore-minimizing benefits for your skin. It is safe and unlikely to cause irritation, but because it is only an average fit for dry sensitive skin, this skin type needs products with richer heavy sealants to lock in moisture.
Sources: [Journal of Controlled Release, 2022](https://pubmed.ncbi.nlm.nih.gov/35150813/)

### What does Water do for dry sensitive skin?

Hard water increases soap deposits and dryness, making dry sensitive skin more prone to irritation and flare-ups. A product of this type needs gentle cleansers and soothing ingredients to calm the skin and protect its moisture barrier against hard water minerals.
Sources: [The Journal of Investigative Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/28927888/), [Clinical and Experimental Allergy, 2021](https://pubmed.ncbi.nlm.nih.gov/33259122/)

### What does Dimethicone do for dry sensitive skin?

Dimethicone helps protect dry sensitive skin, though it may show varying performance compared to other protectants. This type of product needs gentle, hydrating ingredients that support the skin barrier without causing irritation.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. It works for dry sensitive skin, though a product of this type for your skin needs rich moisturizing ingredients to help lock in lasting hydration.

### Can I use this serum with niacinamide, and in what order?

You can use this serum with niacinamide by applying niacinamide first and following with this treatment once it absorbs, as it is safe for your skin type. Because this product works moderately well for dry skin, a product of this type needs extra sealing ingredients to lock in moisture and keep flaky skin soft and smooth.

### How often should I use this serum?

You can use this treatment in your evening routine, as products of this type go in the PM for simplicity and safety around sun exposure. It works for your skin, though dry skin needs richer hydrators and heavy sealing ingredients to lock in moisture.
Sources: [Journal of Controlled Release, 2022](https://pubmed.ncbi.nlm.nih.gov/35150813/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts for dry and sensitive skin as it has a very safe profile without harsh ingredients. However, a product of this type needs richer moisturizing and sealing ingredients to truly nourish flaky areas.
Sources: [Journal of Controlled Release, 2022](https://pubmed.ncbi.nlm.nih.gov/35150813/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [Dewytree Miracle Clear Serum](https://lovi.care/skincare/sg/p/dewytree/miracle-clear-serum/for/dry-sensitive-skin) — High fit — S$33.42 at Amazon
- [SKIN1004 Madagascar Centella Asiatica Ampoule](https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-asiatica-ampoule/for/dry-sensitive-skin) — Average fit — S$54.11 at Amazon
- [Clarins Double Serum](https://lovi.care/skincare/sg/p/clarins/double-serum/for/dry-sensitive-skin) — High fit — S$150.00 at YesStyle

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — S$25.06 at Amazon
- Soothing Toner: [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/sg/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/dry-sensitive-skin) — High fit — S$34.52 at Amazon
- Moisturizer with Sun Protection: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/sg/p/dr-g/green-mild-up-sun/for/dry-sensitive-skin) — Superior fit — S$59.06 at Amazon

## Where to buy

- YesStyle: S$45.08 (https://www.yesstyle.com/en/medicube-zero-pore-serum-2-0-27ml/info.html/pid.1065910164?curr=SGD&rco=SG)
Prices checked 16 Oct 2026.

## Ingredients

Water, Butylene Glycol, Dimethicone Vinyl Dimethicone Crosspolymer, Cyclopentasiloxane, Cetyl Ethylhexanoate, Cyclohexasiloxane, Polysorbate 60, Bis-Peg-18 Methyl Ether Dimethyl Silane, Glyceryl Stearate, Dimethicone, Peg-100 Stearate, Phenoxyethanol, Tromethamine, Chlorphenesin, Polyacrylate-13, Ethylhexylglycerin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Isoceteth-10, Caprylyl Glycol, Isoceteth-25, Carbomer, Polyisobutene, Disodium Edta, Mentha Rotundifolia Leaf Extract, Citrus Aurantifolia Peel Extract, Cymbopogon Schoenanthus Extract, Polysorbate 20, Sorbitan Isostearate, Camellia Japonica Flower Extract, Fomes Officinalis Extract Mushroom Extract, 1,2-Hexanediol, Cinnamomum Zeylanicum Bark Extract, Uncaria Gambir Extract, Nelumbo Nucifera Flower Extract, Pelargonium Graveolens Extract, Sanguisorba Officinalis Root Extract, Bht, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Ulmus Davidiana Root Extract, Oenothera Biennis Flower Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/zero-pore-serum-2-0/for/dry-sensitive-skin