# Medicube Zero Pore Cream 2.0 for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Medicube](https://lovi.care/skincare/sg/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this product utilizes niacinamide to effectively control sebum production and minimize pore appearance, while Centella Asiatica Extract provides soothing benefits.
- Additional ingredients like Camellia Sinensis Leaf Extract and Panthenol further support skin balance and hydration, complementing the primary pore-minimizing function.
- The formulation is safe for your skin, with no reported irritation risks due to the absence of harsh components and the inclusion of calming botanical extracts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Salicylic Acid, Sodium Hyaluronate, Willow Bark Extract, Oil Tree

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Bioactive lipid nanocarriers co-loaded with willow bark or ivy leaf extracts and UV-filters provided pronounced UVA photoprotection up to an SPF-equivalent value of 13 and a maximum in vivo skin hydration effect of 97% when prepared with pomegranate oil. ([Nanomaterials, 2022](https://pubmed.ncbi.nlm.nih.gov/35889587/))
- A topical serum containing 0.5% salicin applied twice daily reduced visible signs of skin aging, including wrinkles and tactile roughness, in 30 female subjects over 12 weeks compared to baseline. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883292/))
- A novel emulsion containing niacinamide, lens esculenta seed extract, and white willow bark extract effectively improved acne, blackheads, and conspicuous facial pores in 30 subjects with oily skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38140770/))
- Topical lycopene-enriched virgin olive oil provides effective pain relief similar to a placebo in patients with burning mouth syndrome, showing a strong placebo effect. ([Journal of Oral Rehabilitation, 2014](https://pubmed.ncbi.nlm.nih.gov/24612248/))

## What reviewers say

Based on a very large amount of data, users with combination and oily skin frequently praise this cream for its ability to balance sebum production while providing deep hydration without a sticky finish. Many report smoother skin texture and a fresh feeling. However, a significant number of reviewers note that visible reduction in pore size is subtle or non-existent despite the product's claims.

- Liked: Excellent hydration (mostly mentioned)
- Liked: Pleasant texture (often mentioned)
- Disliked: Ineffective on pores (often mentioned)
- Liked: Sebum control (sometimes noted)
- Liked: Skin smoothing (sometimes noted)
- Disliked: Strong scent (sometimes noted)
- Disliked: Heavy for some (rarely noted)
- Disliked: Potential irritation (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes medicube Zero Pore Cream a great fit for oily skin?

This cream is a great fit for oily skin because it uses niacinamide to control sebum and minimize pores, while Centella Asiatica extract helps soothe the skin. It also includes panthenol and botanical extracts that support skin balance and hydration without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for oily skin?

This cream is a great fit for your oily skin because it uses niacinamide to control extra oil and shrink pores, alongside soothing Centella Asiatica extract. Additional ingredients like willow bark extract and panthenol help balance your skin and keep it hydrated without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Salicylic Acid do for oily skin?

Salicylic acid helps oily skin by reducing excess oil and keeping pores clear. It may also improve overall skin hydration while managing breakouts.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682377/), [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30972839/)

### Where does this cream go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and toning, and before your moisturizer. Using it at night helps control oil and minimize pores safely while avoiding extra sensitivity around sun exposure.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with retinol, and in what order?

You can use this cream in the same routine as retinol by applying your retinol first, allowing it to absorb, and then following with this cream to help keep your skin balanced and hydrated. This approach is unlikely to cause irritation because the formula includes calming botanical extracts like Centella Asiatica Extract.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this cream?

You can use this treatment in your evening routine. It uses niacinamide and Centella Asiatica Extract to help control oil and keep your oily skin calm and balanced.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this cream clog pores, cause breakouts or purging for oily skin?

This cream is a great fit for oily skin and is unlikely to clog pores or cause breakouts, as it uses niacinamide to control oil and minimize pores. Its gentle botanical extracts and safe formulation keep the skin balanced without causing irritation, though some reviewers have noted it can feel heavy.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Dr. Ceuracle Tea Tree Purifine 95 Essence](https://lovi.care/skincare/sg/p/dr-ceuracle/tea-tree-purifine-95-essence/for/oily-skin) — Superior fit — S$36.36 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — S$50.41 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/oily-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

- YesStyle: S$33.39 (https://www.yesstyle.com/en/medicube-zero-pore-cream-2-0-50ml/info.html/pid.1069062329?curr=SGD&rco=SG)
Prices checked 14 Oct 2026.

## Ingredients

Water, Glycerin, Niacinamide, Butylene Glycol, Cyclopentasiloxane, Dimethicone, Cyclohexasiloxane, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80, Squalane, Tocopheryl Acetate, Panthenol, Allantoin, Centella Asiatica Extract, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Scutellaria Baicalensis Root Extract, Polygonum Cuspidatum Root Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Coptis Japonica Root Extract, Adenosine, Ethylhexylglycerin, Caprylyl Glycol, 1,2-Hexanediol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/zero-pore-cream-2-0/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/zero-pore-cream-2-0/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medicube/zero-pore-cream-2-0/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/zero-pore-cream-2-0/for/oily-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/zero-pore-cream-2-0/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/zero-pore-cream-2-0/for/oily-skin