# Medicube Super Cica Ampoule for oily skin

**Lovi Fit: High fit for oily skin.**
Oily Skin Fit: Superior · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Medicube](https://lovi.care/skincare/sg/brands/medicube)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your oily skin as Centella Asiatica Extract and Madecassoside offer potent anti-inflammatory and barrier-strengthening benefits, directly addressing oily shine and enhancing resilience.
- Licorice Root Extract further supports this by providing soothing effects and helping to regulate oil production, contributing to a more balanced complexion.
- The product demonstrates a high safety profile with no irritation risks for your oily skin, thanks to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/oily-skin): High (this page)
- [Dry skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Madecassoside, Asiatic Acid, Madecassic Acid, Extract Tree

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne. ([International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## What reviewers say

This ampoule is highly effective for users with acne-prone and sensitive skin, frequently noted for its rapid soothing of redness and calming of active breakouts, acting as a significant aid for compromised skin barriers. A notable portion of users express dissatisfaction with its sticky or tacky finish, which can be problematic for morning routines and makeup application.

- Liked: Soothing & calming (mostly mentioned)
- Liked: Acne & blemish care (often mentioned)
- Disliked: Small quantity/price (often mentioned)
- Disliked: Sticky texture (often mentioned)
- Liked: Hydration & glow (sometimes noted)
- Disliked: Packaging/dropper issues (sometimes noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Medicube Super Cica Ampoule a great fit for oily skin?

Medicube Super Cica Ampoule is a great fit because Centella Asiatica Extract and Madecassoside calm redness and strengthen your skin barrier to help control oily shine. Licorice Root Extract further helps balance your complexion by soothing your skin and regulating oil production with a very low risk of irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### Which ingredients make this serum a good fit for oily skin?

Centella Asiatica Extract and Madecassoside help calm redness and strengthen your skin, while Licorice Root Extract helps balance oil production. These ingredients provide a very gentle and safe option for oily skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for oily skin?

Centella Asiatica Extract helps calm redness and keeps oily skin feeling balanced by soothing irritation and supporting moisture levels. It is unlikely to feel heavy, and products of this type for oily skin need ingredients that control excess shine while maintaining hydration.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Madecassoside do for oily skin?

Madecassoside helps soothe oily skin by calming redness and keeping it balanced without feeling heavy. It may also help reduce breakouts and improve the skin barrier, which keeps moisture locked in properly.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Evidence-based Complementary and Alternative Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34845411/)

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening provides simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to calm your skin and strengthen its barrier before putting on retinol. This combination helps keep your skin comfortable while managing any dryness or irritation that stronger products may cause.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after cleansing and toning and before your moisturizer. It is very safe and gentle for oily skin, so you are unlikely to experience any irritation with regular use.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to clog pores or cause breakouts for oily skin, as it has a high safety profile with no irritation risks. Centella Asiatica Extract and Madecassoside help calm the skin and strengthen your moisture barrier, while Licorice Root Extract assists in balancing oil production.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/oily-skin) — High fit — S$50.41 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/oily-skin) — High fit — S$28.55 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/oily-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Centella Asiatica Extract, Water, Glycerin, Butylene Glycol, Methylpropanediol, Glycereth-26, 1,2-Hexanediol, Betaine, Licorice Root Extract, Carbomer, Tromethamine, Glycereth-25 Pca Isostearate, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Allantoin, Glyceryl Acrylate Acrylic Acid Copolymer, Dipropylene Glycol, Panthenol, Gardenia Extract, Adenosine, Propanediol, Polyglyceryl-10 Oleate, Centella Asiatica Root Extract, Centella Asiatica Leaf Extract, Nelumbo Nucifera Extract, Pentylene Glycol, Tree Leaf Water, Madecassoside, Biosaccharide Gum-1, Extract Tree, Asiatic Acid, Madecassic Acid, Asiaticoside, Ectoin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/super-cica-ampoule/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/super-cica-ampoule/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/super-cica-ampoule/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/super-cica-ampoule/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medicube/super-cica-ampoule/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/super-cica-ampoule/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/super-cica-ampoule/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/super-cica-ampoule/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/super-cica-ampoule/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medicube/super-cica-ampoule/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/super-cica-ampoule/for/oily-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/super-cica-ampoule/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/super-cica-ampoule/for/oily-skin