# Medicube Deep Peptide Radiance Mask for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Medicube](https://lovi.care/skincare/sg/brands/medicube)
Category: [Face masks](https://lovi.care/skincare/sg/best/face-masks)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few nourishing masks fit it even better.

## Why this fit

- Highly suitable for your normal skin and addresses redness and irritation effectively due to the high concentration of Centella Asiatica Leaf Extract and its derivatives, which calm inflammation, complemented by niacinamide and panthenol for barrier support and hydration.
- The inclusion of multiple peptides like Acetyl Hexapeptide-1 and hydrating agents such as Glycerin and Hydrolyzed Hyaluronic Acid further enhances the nourishing and soothing benefits for your skin.
- The product is safe for your sensitive skin, featuring soothing ingredients like Centella Asiatica Leaf Extract and Allantoin with no harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/oily-acne-prone-skin): Superior

## Key ingredients

Peptide Complex, Niacinamide, Centella Asiatica Leaf Extract, Hydrolyzed Hyaluronic Acid, Ceramide Np

## What the research says

- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on limited data, users love this mask for its intense hydration and ability to provide an instant glow, making it ideal for dry, dull, or sensitive skin. The peptide-rich essence is praised for plumping fine lines and soothing irritation without a sticky feel. Some users find the price high for frequent use and note the sheet size can be slightly small.

- Liked: Intense hydration (mostly mentioned)
- Liked: Instant radiance (often mentioned)
- Liked: Non-sticky finish (sometimes noted)
- Liked: Soothing and plumping (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Handling difficulty (rarely noted)
- Disliked: Sheet fit issues (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start by using the sheet mask 3 times a week and increase if your skin feels good.
- Apply the sheet mask right after cleansing and toning, but always before your daily moisturizer or SPF.
- Unfold the sheet mask and gently press it onto your face, avoiding any harsh rubbing. Leave it on for ten to fifteen minutes.
- For sensitive skin, apply the sheet mask on completely dry skin to ensure better comfort and tolerance.
- Always avoid the delicate eye area and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes the Deep Peptide Radiance Mask a great fit for sensitive skin?

This mask is a great fit because it is packed with Centella Asiatica leaf extract and allantoin to calm redness and irritation, along with panthenol, niacinamide, and hyaluronic acid to hydrate and support your skin barrier. It has a safe profile with no harsh ingredients, making it very unlikely to cause flare-ups.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this mask a good fit for sensitive skin?

This mask is a great fit for sensitive skin because it contains Centella Asiatica Leaf Extract and allantoin to calm redness and irritation, along with niacinamide and panthenol to support the skin barrier. These soothing ingredients help keep your skin comfortable and hydrated without causing harsh reactions.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Peptide Complex do for sensitive skin?

Peptide complex helps improve hydration and smooths the look of fine lines for sensitive skin without causing irritation. It supports a healthy moisture barrier so skin stays soft and comfortable over time.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335808/), [Frontiers in Medicine, 2026](https://pubmed.ncbi.nlm.nih.gov/41924746/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this mask go in a skincare routine for sensitive skin?

This nourishing mask fits into your weekly routine as a step on wash days, after cleansing and exfoliating, and before applying your treatment and moisturizer. It is unlikely to irritate your sensitive skin, helping to calm redness and support your moisture barrier.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this mask with retinol, and in what order?

Yes, you can use this mask with retinol to help calm irritation and support your moisture barrier. Apply the mask after cleansing and toning, and follow with your retinol treatment and a moisturizer.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### How often should I use this mask?

You can use this nourishing mask once a week as part of your weekly routine. It is a great fit for sensitive skin and helps calm redness and irritation while supporting moisture.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can this mask clog pores, cause breakouts or purging for sensitive skin?

This mask is a great fit for sensitive skin and is unlikely to clog pores or cause breakouts because it features calming ingredients like Centella Asiatica Leaf Extract and allantoin without any harsh substances. Clinical studies show that hydrating ingredients such as glycerin and hyaluronic acid support skin barrier recovery and moisture without causing congestion.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Behenyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [By Wishtrend Natural Vitamin 21.5% Enhancing Sheet Mask](https://lovi.care/skincare/sg/p/by-wishtrend/natural-vitamin-21-5-enhancing-sheet-mask/for/sensitive-skin) — High fit — S$46.64 at Amazon
- [Etude House 0.2mm Therapy Air Mask](https://lovi.care/skincare/sg/p/etude-house/0-2mm-therapy-air-mask/for/sensitive-skin) — Average fit — S$10.99 at Amazon
- [Anua Heartleaf 77% Soothing Sheet Mask](https://lovi.care/skincare/sg/p/anua/heartleaf-77-soothing-sheet-mask/for/sensitive-skin) — Superior fit — S$3.35 at YesStyle

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

- YesStyle: S$3.85 (https://www.yesstyle.com/en/medicube-deep-peptide-radiance-mask-27ml/info.html/pid.1124066761?curr=SGD&rco=SG)
Prices checked 17 Oct 2026.

## Ingredients

Water, Dipropylene Glycol, Glycerin, Butylene Glycol, Niacinamide, 1,2-Hexanediol, Cetyl Ethylhexanoate, Panthenol, Allantoin, Xylitol, Centella Asiatica Leaf Extract, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Bifida Lysate Ferment, Caprylyl Glycol, Sorbitan Laurate, Hydrogenated Lecithin, Hydrolyzed Hyaluronic Acid, Tocopherol, Asiaticoside, Madecassic Acid, Asiatic Acid, Acetyl Dipeptide-1, Cetyl Ester, Acetyl Hexapeptide-1, Palmitoyl Tripeptide-5, Beta-Glucan, Ceramide Np, Acetyl Octapeptide-3, Hydrogenated Oil, Behenyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Arginine, Carbomer, Adenosine, Hydroxyethylcellulose, Ethylhexylglycerin, Disodium Edta
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/deep-peptide-radiance-mask/for/sensitive-skin