# Medi-Peel Cica Antio Cream for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Medi-Peel](https://lovi.care/skincare/sg/brands/medi-peel)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/sg/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate benefits for your acne, blemishes, and breakouts, as niacinamide and Centella Asiatica Extract provide anti-inflammatory and seboregulating actions suitable for combination skin.
- The inclusion of hyaluronic acid and licorice root extract further supports hydration and soothing, contributing to overall skin health.
- The product is safe for your acne-prone skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Centella Asiatica Extract, Niacinamide, Sodium Hyaluronate, Squalane, Ceramide Np

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion. ([International Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18717861/))
- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

This cream is widely praised as a rescue treatment for damaged skin barriers, effectively calming redness and inflammation associated with acne and sensitivity. While many users with dry or combination skin love its deep hydration and healing properties, those with very oily skin sometimes find the texture too heavy or occlusive, occasionally leading to clogged pores.

- Liked: Soothes redness (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Disliked: Poor packaging (often mentioned)
- Liked: Improves acne (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Sticky/heavy finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Ineffective for some (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medi-Peel Cica Antio work for acne-prone skin?

Medi-Peel Cica Antio Cream works moderately well for acne-prone skin, as Niacinamide and Centella Asiatica Extract help calm breakouts and balance oil. To fit acne-prone skin even better, a moisturizing treatment needs highly effective blemish-clearing ingredients, gentle soothing components, and a lightweight texture that keeps skin balanced without clogging pores.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this cream a good fit for acne-prone skin?

Niacinamide and Centella Asiatica Extract help calm breakouts and balance oil on acne-prone skin. To work best for this skin type, a moisturizing treatment needs effective blemish-fighting ingredients, soothing extracts, and lightweight hydration that will not cause irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes near the end of your morning and evening routines after your cleanser and toners. Products for acne-prone skin need soothing ingredients like Centella Asiatica Extract and niacinamide, along with lightweight hydrators that calm breakouts without clogging pores.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol by applying it either before or after your retinol to help calm irritation and keep your skin comfortable. Using a gentle moisturizer alongside retinoids helps support your skin barrier and makes the routine much easier to tolerate. For this skin, a product of this type needs lightweight hydrators and soothing plant extracts that calm breakouts without clogging pores.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24930436/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your morning and evening routine. Regular application helps keep acne-prone skin hydrated while soothing breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts for acne-prone skin, though some users report a sticky or heavy finish. Acne-prone skin typically does best with lightweight, oil-free hydration and targeted blemish-clearing ingredients that keep pores completely clear without feeling heavy.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body, as its gentle ingredients are safe for delicate areas. A product of this type needs lightweight hydration, soothing plant extracts, and barrier-supporting ingredients to properly care for thin or body skin.

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (hexyl cinnamal, limonene, linalool, and citronellol). Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [LANEIGE Water Bank Moisture Cream](https://lovi.care/skincare/sg/p/laneige/water-bank-moisture-cream/for/acne-prone-skin) — Average fit — S$38.31 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/sg/p/l-occitane/immortelle-divine-cream/for/acne-prone-skin) — Average fit — S$103.92 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Cream](https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-cream/for/acne-prone-skin) — Average fit — S$45.46 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sg/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — S$36.14 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Dipropylene Glycol, Niacinamide, Glyceryl Stearate, Peg-100 Stearate, Betaine, Sorbitan Stearate, Arginine, Carbomer, Hydroxyacetophenone, Dimethicone, Caprylyl Glycol, Melia Azadirachta Leaf Extract, Dipotassium Glycyrrhizate, Wheat Extract Sprout, Centella Asiatica Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Ethylhexylglycerin, Curcuma Longa Root Extract, Eclipta Prostrata Extract, Adenosine, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Glyceryl Acrylate Acrylic Acid Copolymer, Solanum Melongena Fruit Extract, Disodium Edta, Allantoin, Aloe Barbadensis Flower Extract, Tocopheryl Acetate, Panthenol, Propylene Glycol, Propanediol, Beta-Glucan, Squalane, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Fructan, Butylene Glycol, Sodium Hyaluronate Crosspolymer, Glyceryl Polymethacrylate, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Butyrospermum Parkii Butter Shea Butter, 1,2-Hexanediol, Olea Europaea Leaf Extract Olive Leaf Extract, Mannan, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Dandelion Leaf Extract, Benzyl Glycol, Ceramide Np, Phytosphingosine, Hydrolyzed Hyaluronic Acid, Rosa Damascena Flower Extract, Rhodiola Rosea Root Extract, Origanum Vulgare Leaf Extract, Palmitoyl Tripeptide-5, Chamaecyparis Obtusa Leaf Extract, Willow Bark Extract, Usnea Barbata Extract, Zanthoxylum Piperitum Fruit Extract, Pulsatilla Koreana Extract, Lactobacillus Soybean Extract Ferment, Portulaca Oleracea Extract, Citric Acid, Cinnamomum Cassia Bark Extract, Scutellaria Baicalensis Root Extract, Raspberry Ketone, Acetyl Hexapeptide-8, Copper Tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, Hexyl Cinnamal, Limonene, Linalool, Citronellol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medi-peel/cica-antio-cream/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/medi-peel/cica-antio-cream/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medi-peel/cica-antio-cream/for/acne-prone-skin