# Mederma Advanced Scar Gel for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Mederma](https://lovi.care/skincare/sg/brands/mederma)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Offers moderate scar treatment for your normal skin, as onion bulb extract and allantoin work to smooth texture and reduce redness, though these ingredients do not directly address your primary concern of wrinkles and fine lines.
- Panthenol and sodium hyaluronate provide beneficial hydration and barrier support, which are excellent for normal skin.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/oily-acne-prone-skin): Average

## Key ingredients

Allantoin, Onion Extract, Sodium Hyaluronate, Panthenol, Peg-200

## What the research says

- Topical onion extract improved scar colour compared to silicon gel, while silicon gel was superior in decreasing scar height in 60 patients with hypertrophic and keloid scars, with the most effective results obtained from combining onion extract and silicon gel. ([Journal of Wound Care, 2007](https://pubmed.ncbi.nlm.nih.gov/17722521/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Silicone derivative plus onion extract gel reduced pain, itching, and pigmentation compared to placebo in patients after median sternotomy. ([International Wound Journal, 2012](https://pubmed.ncbi.nlm.nih.gov/22168750/))
- Topical 12% onion extract gel applied early on Pfannenstiel's cesarean section scars in Asians improved scar height and scar symptoms compared to placebo, with no significant difference in scar redness, pliability, or overall appearance. ([Dermatology Research and Practice, 2012](https://pubmed.ncbi.nlm.nih.gov/22924037/))
- Onion extract gel significantly improved scar softness, redness, texture, and global appearance compared to no treatment in 60 subjects with postsurgical scars on the upper chest over 10 weeks. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18482012/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical excipients like propylene glycol, polyethylene glycol 200, and octisalate alter the stratum corneum recovery, lateral diffusion, and in vitro flux of ibuprofen in humans. ([Journal of Pharmaceutical Sciences, 2014](https://pubmed.ncbi.nlm.nih.gov/24421242/))

## What reviewers say

Based on a very large amount of data, users consistently report that this gel effectively softens, flattens, and fades the discoloration of various scar types, including acne pockmarks, surgical incisions, and burns. While results are widely praised, they are heavily dependent on long-term consistency, with visible improvements typically requiring 4 to 8 weeks for new scars and several months for older ones.

- Liked: Effective scar fading (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Disliked: Slow results (often mentioned)
- Liked: Easy application (sometimes noted)
- Liked: Versatile treatment (sometimes noted)
- Disliked: Flaking or peeling (sometimes noted)
- Disliked: Minor irritation (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Mederma Advanced Scar Gel a great fit for mature skin?

Mederma Advanced Scar Gel is a great fit because panthenol and sodium hyaluronate provide beneficial hydration and barrier support. Additionally, onion bulb extract and allantoin work to smooth texture and reduce redness.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this gel a good fit for mature skin?

Panthenol and sodium hyaluronate make this gel a good fit for mature skin by providing deep hydration and supporting the skin barrier. Allantoin and onion extract also help to smooth texture and reduce redness.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Allantoin do for mature skin?

Allantoin helps soothe dry and irritated mature skin while supporting a smooth and healthy skin barrier. This ingredient may improve overall skin softness and comfort, making it a helpful addition to daily anti-aging routines.
Sources: [Pharmaceutics, 2026](https://pubmed.ncbi.nlm.nih.gov/41900878/), [Journal of Functional Biomaterials, 2021](https://pubmed.ncbi.nlm.nih.gov/34842756/)

### What does Onion Extract do for mature skin?

Onion extract helps mature skin by providing powerful antioxidants that fight oxidative stress and inflammation while supporting a smooth, even look. It may also help prevent excess scarring and maintain firmness by balancing collagen production and cell growth. A product for this skin type needs nourishing ingredients and antioxidants to protect against aging and keep the skin soft.
Sources: [Naunyn-Schmiedeberg's Archives of Pharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39738831/), [International Journal of Molecular Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20127038/)

### Where does this gel go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps usage simple and avoids sun exposure concerns. It is safe for this skin, providing hydration and barrier support with a low risk of irritation.

### Can I use this gel with retinol, and in what order?

You can use this gel in your routine, applying your treatment step at night after cleansing and toning, and following with your moisturizer. Panthenol and sodium hyaluronate in the formula provide helpful hydration and barrier support that is unlikely to cause irritation.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this gel?

You can use this gel in your evening routine, as treatments fit best at night for simplicity and extra safety around sun exposure. It is safe for your skin with no risk of irritation, helping to smooth texture and reduce redness.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can this gel clog pores, cause breakouts or purging for mature skin?

This gel is unlikely to clog pores or cause breakouts for mature skin because it lacks harsh or heavy ingredients that typically trigger irritation or block pores. It is generally safe for your skin type, though it focuses more on smoothing scars than on targeting wrinkles and fine lines.

### Is this gel fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol).

## Alternatives for mature skin

- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/sg/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — S$110.11 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — S$50.41 at Amazon
- [PCA Skin C&E Strength Max](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-strength-max/for/mature-skin) — High fit — S$179.75 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Peg-200, Alcohol, Xanthan Gum, Onion Bulb Extract, Lecithin, Methylparaben, Sorbic Acid, Panthenol, Sodium Hyaluronate, Allantoin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mederma/advanced-scar-gel/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/mederma/advanced-scar-gel/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/mederma/advanced-scar-gel/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/mederma/advanced-scar-gel/for/mature-skin
- France: https://lovi.care/skincare/fr/p/mederma/advanced-scar-gel/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/mederma/advanced-scar-gel/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/mederma/advanced-scar-gel/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/mederma/advanced-scar-gel/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/mederma/advanced-scar-gel/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/mederma/advanced-scar-gel/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/mederma/advanced-scar-gel/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/mederma/advanced-scar-gel/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mederma/advanced-scar-gel/for/mature-skin