ma:nyo Heather Calming Essence for oily acne-prone skin

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Questions and answers

What the research says

• Treatment with a facial cream gel containing a biotechnological phytocomplex, niacinamide, and succinic acid increased skin microbial diversity and reduced C. acnes abundance, lesion counts, sebum, and acne severity in 44 subjects with mild-moderate acne over 56 days.

  Journal of Cosmetic Dermatology, 2024

• Treatment with a lotion containing a phytocomplex, niacinamide, and succinic acid increased skin microbial alpha diversity, reduced Cutibacterium acnes relative abundance, and improved acne severity and clinical symptoms in 43 subjects with truncal mild-moderate acne.

  Skin Research and Technology, 2024

• A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.

  Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020

• Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.

  American Journal of Clinical Dermatology, 2002

• Topical pretreatment with Calluna vulgaris and red grape seed extracts decreased GSH formation and glutathione peroxidase activity, inhibited lipid peroxidation and nitric oxide production, and reduced caspase 3 activity in UVB-irradiated SKH-1 mouse skin.

  Journal of Medicinal Food, 2011

• Topical application of Calluna vulgaris and Vitis vinifera extracts reduced UVB-induced cyclobutane pyrimidine dimers, sunburn cells, and inflammatory cytokines (IL-6 and TNF-alpha) in SKH-1 hairless mice compared to UVB irradiation alone.

  Journal of Physiology and Pharmacology, 2011

• Topical application of Calluna vulgaris extract modulated NF-κB/ERK signaling and reduced MMP-9 activity and secretion in SKH-1 hairless mice skin exposed to single or multiple doses of UVB irradiation.

  Journal of Physiology and Pharmacology, 2012

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

Why other serums fit oily acne-prone skin better

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne.

  International Journal of Pharmaceutics, 2024

Ingredients

Calluna Vulgaris Extract, Glycerin, Butylene Glycol, Erythritol, Rutin, Allantoin, Aspalathus Linearis Leaf Extract, Hyaluronic Acid, Aureobasidium Pullulans Ferment, Chrysanthemum Indicum Flower Extract, Chlamydomonas Extract, Chitosan, Lactobacillus Ferment, Leuconostoc Radish Root Ferment Filtrate, Panthenol, Trehalose, Beta-Glucan, Cholesterol, Ceramide Np, Glycereth-26, Pentylene Glycol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Diethoxyethyl Succinate, Propanediol, Dipotassium Glycyrrhizate, Succinic Acid, Tromethamine, 1,2-Hexanediol, Ethylhexylglycerin, Xylitol, Water, Biosaccharide Gum-4, Dipropylene Glycol, Tocopherol, Hydrogenated Lecithin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.