# La Roche-Posay Cicaplast Gel B5 for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [La Roche-Posay](https://lovi.care/skincare/sg/brands/la-roche-posay)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for mature skin.

## Why this fit

- Highly suitable for your normal skin as glycerin and panthenol provide humectant action and barrier repair, addressing your concerns about wrinkles and fine lines by supporting skin elasticity.
- The formulation offers excellent barrier resilience due to the presence of panthenol and madecassoside, which support skin repair and hydration.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/oily-acne-prone-skin): High

## Key ingredients

Panthenol B5, Glycerin, Madecassoside, Zinc Gluconate, Sodium Hyaluronate

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Hyaluronic acid extracts are safe and efficacious products for skin repair when used in tissue regeneration alone or in combination with herbal or Western medicine. ([Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Panthenyl triacetate (PTA) demonstrated skin de-acetylation into panthenol, stimulated energetic and synthesis metabolic pathways, and achieved a statistically significant improvement in wound healing after 72 hours compared to saline treatment in human volunteers, outperforming panthenol in long-lasting wound healing action. ([Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/22487447/))
- A comprehensive topical regimen incorporating niacinamide, Pro-Xylane, and panthenol following PicoWay laser treatment decreased transepidermal water loss, increased hydration and skin elasticity, reduced wrinkles and redness, and improved skin tone in 88 Chinese females compared to a standard care control group. ([Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41487026/))
- Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/))
- Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers. ([Experimental Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23947673/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users find this gel to be a lightweight, non-greasy option for repairing skin barriers, particularly beneficial for oily or acne-prone skin. It is highly effective for healing post-procedure skin, soothing irritation from treatments like retinoids, and protecting compromised skin. Some users note a shiny finish that may not be ideal for daytime wear.

- Liked: Accelerates healing (mostly mentioned)
- Liked: Lightweight & non-greasy (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Liked: Safe for acne-prone (sometimes noted)
- Disliked: Shiny/tacky finish (sometimes noted)
- Disliked: Small size/price (sometimes noted)
- Disliked: Makeup incompatibility (rarely noted)
- Disliked: Not moisturizing enough (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes La Roche-Posay Cicaplast Gel B5 a great fit for mature skin?

La Roche-Posay Cicaplast Gel B5 is a great fit for mature skin because glycerin and panthenol draw in moisture and help repair the skin barrier, which supports skin elasticity to address wrinkles and fine lines. The formula also includes madecassoside to further support skin repair and hydration, keeping the skin safe and comfortable without irritation.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Which ingredients make this treatment a good fit for mature skin?

Glycerin, panthenol, and madecassoside make this treatment a great fit for mature skin by helping lock in moisture, supporting skin repair, and keeping the skin barrier resilient. These ingredients help soften the look of fine lines and wrinkles while maintaining a very safe, gentle routine.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### What does Panthenol do for mature skin?

Panthenol helps mature skin by increasing moisture, improving skin elasticity, and reducing the look of wrinkles. It also supports skin barrier recovery and calms redness with a very safe profile.
Sources: [Lasers in Medical Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42686896/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this treatment go in a skincare routine for mature skin?

This treatment goes in the evening routine, placed after cleansing and toning and right before your moisturizer. Putting it on at night keeps things simple and avoids extra safety concerns with sun exposure.

### Can I use this treatment with retinol, and in what order?

Yes, you can use this treatment with retinol by applying it after your retinol product to help keep your skin calm and hydrated. The gentle ingredients provide great support for skin repair and comfort without causing irritation.

### How often should I use this treatment?

This treatment works best when used in the evening as part of your routine. It is unlikely to cause irritation and helps keep your skin soft while supporting elasticity.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Can this treatment clog pores, cause breakouts or purging for mature skin?

La Roche-Posay Cicaplast Gel B5 is unlikely to cause breakouts or clog pores for mature skin because it has an excellent safety profile without harsh ingredients. Glycerin and panthenol help keep your skin hydrated and smooth while supporting your skin barrier.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Drunk Elephant A-Passioni Retinol Cream](https://lovi.care/skincare/sg/p/drunk-elephant/a-passioni-retinol-cream/for/mature-skin) — High fit — S$110.11 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — S$50.41 at Amazon
- [PCA Skin C&E Strength Max](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-strength-max/for/mature-skin) — High fit — S$179.75 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

- YesStyle: S$16.23 (https://www.yesstyle.com/en/la-roche-posay-cicaplast-baume-b5-ultra-repairing-soothing-balm/info.html/pid.1125793072?curr=SGD&rco=SG)
Prices checked 13 Oct 2026.

## Ingredients

Water, Glycerin, Dimethicone, Panthenol, Pentylene Glycol, C30-45 Alkyl Dimethicone, Polybutene, Sodium Citrate, Peg Ppg-18 18 Dimethicone, Zinc Gluconate, Madecassoside, Dimethiconol, Manganese Gluconate, Sodium Hyaluronate, Copper Gluconate, Caprylyl Glycol, Citric Acid, Polysorbate 20, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/cicaplast-gel-b5/for/mature-skin