# iS Clinical Cleansing Complex for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [iS Clinical](https://lovi.care/skincare/sg/brands/is-clinical)
Category: [Cleansers](https://lovi.care/skincare/sg/best/cleansers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few cleansers fit it even better.

## Why this fit

- Excellent suitability for your combination skin and acne concerns is provided by willow bark extract and saccharum officinarum extract, which offer effective pore decongestion and mild exfoliation. Asiaticoside, asiatic acid, and madecassic acid further target blemishes and breakouts with their therapeutic properties.
- Glycerin and chamomile extract ensure adequate hydration and soothing effects, complementing the cleansing action of disodium laureth sulfosuccinate for a balanced experience.
- The product is safe for your skin, featuring a gentle formula free from harsh irritants and enriched with soothing chamomile.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/oily-skin): Superior
- [Dry skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/combination-skin): Superior
- [Sensitive skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin): Superior

## Key ingredients

Willow Bark Extract, Asiaticoside, Madecassic Acid, Ascorbyl Palmitate, Tocopheryl Acetate

## What the research says

- Asiatic acid-loaded solid lipid microparticles stabilized with poloxamer-188 reduced porphyrin intensity, enhanced skin barriers, and improved skin hydration and brightness in fifteen participants with mild-to-moderate acne. ([International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/))
- A botanical face cleanser with hops and willow bark extract continuously reduced skin sebum levels without reactive seborrhea after treatment in 21 healthy volunteers compared to a sodium laureth sulfate cleanser, with neither cleanser causing skin irritation. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Bioactive lipid nanocarriers co-loaded with willow bark or ivy leaf extracts and UV-filters provided pronounced UVA photoprotection up to an SPF-equivalent value of 13 and a maximum in vivo skin hydration effect of 97% when prepared with pomegranate oil. ([Nanomaterials, 2022](https://pubmed.ncbi.nlm.nih.gov/35889587/))
- A topical serum containing 0.5% salicin applied twice daily reduced visible signs of skin aging, including wrinkles and tactile roughness, in 30 female subjects over 12 weeks compared to baseline. ([Journal of Cosmetic Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20883292/))
- A novel emulsion containing niacinamide, lens esculenta seed extract, and white willow bark extract effectively improved acne, blackheads, and conspicuous facial pores in 30 subjects with oily skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38140770/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## What reviewers say

Based on a very large amount of data, this gel cleanser is widely celebrated for balancing deep cleansing with gentle hydration, making it particularly effective for acne-prone or sensitive skin. Users consistently report that it refines texture and minimizes pores without stripping the skin's natural moisture barrier.

- Liked: Gentle and non-stripping (mostly mentioned)
- Liked: Clears acne/pores (often mentioned)
- Liked: Versatile multitasker (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Can be drying (rarely noted)
- Disliked: Makeup removal issues (rarely noted)

## How to apply

- Could be used as part of your AM and PM routine. Start using it 3 times a week and build up to daily use if your skin tolerates it.
- This cleanser is the first step in your morning routine and the second step after your pre-cleanser in the evening. Always follow up with a toner and moisturizer .
- Gently massage a small amount of the cleanser onto your face in circular motions. Avoid harsh rubbing to keep your skin calm.
- Apply the cleanser on slightly damp skin to help it work effectively against breakouts. Rinse thoroughly with lukewarm water .
- Avoid the immediate eye area and do a patch test before your first use to check for any sensitivity.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### What makes iS Clinical Cleansing Complex a great fit for acne-prone skin?

iS Clinical Cleansing Complex is a great fit because willow bark extract and sugarcane extract clear out pores and gently exfoliate, while centella extracts target breakouts. Glycerin and chamomile also help keep your skin calm and hydrated without irritation.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### Which ingredients make this cleanser a good fit for acne-prone skin?

Willow bark extract and saccharum officinarum extract make this cleanser a great fit by clearing out pores and gently smoothing the skin, while asiaticoside, asiatic acid, and madecassic acid help target blemishes and breakouts.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/)

### What does Willow Bark Extract do for acne-prone skin?

Willow bark extract helps calm inflammation and clears excess oil to improve acne and blackheads. This ingredient is unlikely to cause skin irritation while working to keep your skin smooth and clear.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/), [Planta Medica, 2019](https://pubmed.ncbi.nlm.nih.gov/30690691/)

### What does Asiaticoside do for acne-prone skin?

Asiaticoside helps calm acne-prone skin and supports healing by acting on the biological pathways involved in skin inflammation and blemishes. It works best when paired with soothing ingredients and gentle hydration to keep the skin barrier balanced without irritation.
Sources: [Evidence-based Complementary and Alternative Medicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34845411/)

### Where does this cleanser go in a skincare routine for acne-prone skin?

This cleanser fits into both your morning and evening routines as the first cleansing step, or as the second step in the evening after removing makeup. It helps clear pores and calm breakouts while keeping your skin balanced and hydrated.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Can I use this cleanser with retinol, and in what order?

Yes, you can use this cleanser in your routine with retinol, applying the cleanser first to gently wash your face before your retinol treatment. This cleanser is a great fit for your acne-prone skin because willow bark extract and fruit extracts help clear out pores and keep breakouts calm.
Sources: [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### How often should I use this cleanser?

You can use this cleanser twice a day as part of your morning and evening routine. Using a gentle cleanser regularly helps keep pores clear and calms breakouts without causing irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Can this cleanser clog pores, cause breakouts or purging for acne-prone skin?

This cleanser is a great fit for acne-prone skin because willow bark extract and sugarcane extract help clear out pores and gently exfoliate, while centella extracts target breakouts. It is unlikely to clog pores or cause issues since its gentle formula features soothing chamomile and avoids harsh irritants.
Sources: [International Journal of Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/38460769/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30022595/)

### Can I use this cleanser around the eyes or on my body?

Yes, you can use this cleanser on your body, but it is generally best to avoid the thin skin directly around the eyes. Because the eyelid is one of the thinnest areas of the body, strong cleansers may cause irritation there.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cleanser fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/acne-prone-skin) — Superior fit — S$30.00 at Amazon
- [Lagom Cellup Gel To Water Cleanser](https://lovi.care/skincare/sg/p/lagom/cellup-gel-to-water-cleanser/for/acne-prone-skin) — High fit — S$29.31 at Amazon

## Pairs well with

- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — S$33.87 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sg/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — S$36.14 at Amazon

## Where to buy

- Amazon.sg: S$68.81 (https://www.amazon.sg/dp/B0026TOCK2?tag=lovi-care-web-product0e-22&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Disodium Laureth Sulfosuccinate, Cocamidopropyl Betaine, Peg-30 Glyceryl Cocoate, Glycerin, Propylene Glycol, Hydroxyethylcellulose, Willow Bark Extract, Saccharum Officinarum Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Asiaticoside, Asiatic Acid, Madecassic Acid, Ascorbyl Palmitate, Tocopheryl Acetate, Retinyl Palmitate, Iodopropynyl Butylcarbamate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/is-clinical/cleansing-complex/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/is-clinical/cleansing-complex/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/is-clinical/cleansing-complex/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/is-clinical/cleansing-complex/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/is-clinical/cleansing-complex/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/is-clinical/cleansing-complex/for/acne-prone-skin