# Good Molecules Mandelic Acid Serum for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Good Molecules](https://lovi.care/skincare/sg/brands/good-molecules)
Category: [Exfoliants](https://lovi.care/skincare/sg/best/exfoliators)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few products fit it even better.

## Why this fit

- Highly suitable for your combination skin, this serum utilizes mandelic acid for gentle exfoliation and glycerin for humectant action, effectively balancing both oily and dry areas. Allantoin and panthenol further soothe your acne-prone skin, ensuring a comfortable experience.
- The high concentration of mandelic acid offers excellent exfoliation, smoothing texture and decongesting pores to address your concerns with acne and blemishes.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/oily-acne-prone-skin): High

## Key ingredients

Mandelic Acid, Hyaluronic Acid, Glycerin, Panthenol, Allantoin

## What the research says

- Treatment with 45% mandelic acid peel showed nearly equal overall efficacy as 30% salicylic acid peel in patients with mild-to-moderate facial acne vulgaris, but with fewer adverse effects. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Commonly used chemical peels showed no significant differences in effectiveness for acne vulgaris in most comparisons, though combined salicylic and mandelic acid peeling was superior to glycolic acid and glycolic acid was superior to placebo, based on twelve randomized controlled trials. ([BMJ Open, 2018](https://pubmed.ncbi.nlm.nih.gov/29705755/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Chemical peels using 35% glycolic acid, 20% salicylic-10% mandelic acid, and phytic acid reduce acne scores by 70.55%, 74.14%, and 69.7% respectively, and significantly decline the postacne hyperpigmentation index in Asian patients with mild to moderate acne. ([Journal of Cutaneous and Aesthetic Surgery, 2019](https://pubmed.ncbi.nlm.nih.gov/31619887/))
- Treatment with 30% lactic acid peel showed a significantly greater reduction in pigmentation and higher patient satisfaction compared to 30% mandelic acid peel in patients with periorbital melanosis. ([Indian Dermatology Online Journal, 2025](https://pubmed.ncbi.nlm.nih.gov/41051381/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on limited data, this serum is frequently praised by users with sensitive or acne-prone skin for its gentle exfoliation that smooths texture without irritation. A significant portion of users dislike the cosmetic elegance, citing a sticky finish and pilling issues when layered with other skincare.

- Liked: Affordable price (often mentioned)
- Liked: Gentle exfoliation (often mentioned)
- Disliked: Sticky finish (often mentioned)
- Liked: Clears acne (sometimes noted)
- Liked: Smooths texture (sometimes noted)
- Disliked: Pilling issues (sometimes noted)
- Disliked: Caused breakouts (rarely noted)

## How to apply

- Use this exfoliant PM once a week to start, and gradually increase if your combination skin tolerates it well. Always apply SPF the next morning to protect your clear skin.
- Apply the exfoliant after cleansing and toning, but right before your moisturizer step. This ensures the treatment targets blemishes effectively.
- Gently press 2-3 drops of the exfoliant into your skin without rubbing. Let it absorb for a minute before moving to the next step.
- Apply the exfoliant on clean, dry skin to help control breakouts safely. Since your skin is not sensitive, this dry application method ensures good product absorption.
- Avoid the sensitive eye area and do a patch test before your first use. Do not mix this exfoliant with other strong acids in the same routine.
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### What makes Good Molecules Mandelic Acid Serum a great fit for acne-prone skin?

Good Molecules Mandelic Acid Serum is a great fit because it uses mandelic acid to gently exfoliate, smooth texture, and clear out pores for acne-prone skin. It is very unlikely to cause irritation thanks to soothing ingredients like allantoin and panthenol, which keep skin comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this serum a good fit for acne-prone skin?

Mandelic acid is the key ingredient that makes this serum a great fit by smoothing texture and clearing out pores, while allantoin and panthenol help calm the skin. This combination is unlikely to cause irritation and supports an effective, comfortable routine.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Mandelic Acid do for acne-prone skin?

Mandelic acid helps clear acne and smooth the skin by gently exfoliating and calming breakouts with fewer side effects than many other acids. It is unlikely to cause heavy irritation, and combining it with other treatments may improve stubborn acne and dark spots even further.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35388606/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does it go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, starting at once a week so your skin can adjust. Using it this way helps smooth texture and unclog pores while keeping your skin calm, and is unlikely to cause irritation.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this exfoliant first and following with your retinol on alternate nights to prevent irritation. Combining active ingredients gradually helps your acne-prone skin stay smooth and calm.

### How often should I use it?

Start by using this treatment once a week in the evening, and if your skin tolerates it well and you see good results, you may carefully use it more often. The product features mandelic acid for gentle exfoliation and soothing ingredients that help ensure a comfortable experience with no risk of irritation.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum helps clear clogged pores and smooth texture for acne-prone skin, though a small number of shoppers report occasional breakouts. Its gentle formula is unlikely to cause irritation because it leaves out harsh ingredients while including soothing components.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31553119/), [BMJ Open, 2018](https://pubmed.ncbi.nlm.nih.gov/29705755/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/acne-prone-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/acne-prone-skin) — High fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/acne-prone-skin) — Superior fit — S$168.51 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/sg/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — S$33.87 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Mandelic Acid, Glycerin, Butylene Glycol, Hyaluronic Acid, Sodium Pca, Panthenol, Allantoin, 1,2-Hexanediol, Caprylyl Glycol, Ethylhexylglycerin, Tetrasodium Glutamate Diacetate, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin
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- Australia: https://lovi.care/skincare/au/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/mandelic-acid-serum/for/acne-prone-skin
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