# Good Molecules Gentle Retinol Cream for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Good Molecules](https://lovi.care/skincare/sg/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your normal skin, as bakuchiol and retinol provide antioxidant activity and desquamation regulation, but it lacks sufficient humectant ingredients for optimal hydration.
- The presence of Allantoin and Camellia Sinensis Leaf Extract offers supportive benefits for your redness and irritation, providing general skincare benefits like hydration and soothing.
- The formulation is safe for your sensitive skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Bakuchiol, Glycerin, Acmella Oleracea Extract, Vitis Vinifera Seed Oil Grape Seed Oil

## What the research says

- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical application of a serum containing supramolecular Bakuchiol and Terminalia chebula extract significantly improved barrier function, reduced redness and sensitivity, and improved wrinkles and elasticity in 34 Chinese subjects with sensitive skin after 28 days. ([Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/))
- An Acmella oleracea extract-loaded glycolipid emulsion serum applied topically demonstrated safety with no ocular irritation or systemic dermal absorption, alongside significant improvements in facial skin hydration, smoothness, and reductions in roughness, scaliness, and wrinkles. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39617635/))
- An all-natural anti-wrinkle emulsion serum containing Acmella oleracea extract demonstrated safe skin tolerability and reduced facial wrinkles in human volunteers after 2 weeks of application. ([International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/34297422/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Bakuchiol functions as an anti-aging compound through retinol-like regulation of gene expression, producing significant improvements in lines, wrinkles, pigmentation, elasticity, firmness, and photo-damage after 12 weeks of twice-a-day facial application without usual retinol therapy-associated undesirable effects. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24471735/))
- A nature-based bakuchiol-containing cleanser and moisturizer improved visual and tactile smoothness, clarity, radiance, overall appearance, global anti-aging, and skin moisture content by 16% in 60 female subjects with sensitive mild to moderate photodamaged skin over 4 weeks. ([Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33346506/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- A novel formulation containing supramolecular retinol plus acmella oleracea extract significantly reduced dark circles by 13.8% in melanin index, decreased fine wrinkles, and increased skin firmness by 13.0% in 33 Chinese urban women after 6 weeks of use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34806292/))
- The optimized squalane-based spilanthol emulsion achieved a maximum skin retention of 118.71 μg/g and restored skin hydroxyproline content to 23.99 μg/g, outperforming positive and negative groups due to high drug release and miscibility driven by weak Van der Waals interactions. ([AAPS PharmSciTech, 2019](https://pubmed.ncbi.nlm.nih.gov/31222590/))
- Treatment with methanolic extract of Acmella oleracea leaves exerted potent antioxidant, anti-inflammatory, antimicrobial, and wound healing effects in vitro by reducing inflammatory mediators, scavenging free radicals, inhibiting bacterial growth, and enhancing fibroblast migration without inducing cytotoxicity. ([Journal of Ethnopharmacology, 2025](https://pubmed.ncbi.nlm.nih.gov/39357584/))
- Grapeseed oil-loaded dermocosmetic nanoemulgel applied on the cheeks of healthy volunteers significantly reduced skin melanin, erythema, sebum production, and pores while increasing moisture and elasticity compared to a placebo. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35713012/))
- Topical treatment with cranberry oil and grape oil improved wound healing in rats, with cranberry oil showing an 88.1% wound area reduction and grape oil showing 84.6% compared to 74.1% in controls and 78.4% in the mupirocin standard group on day 13. ([Phytotherapy Research, 2011](https://pubmed.ncbi.nlm.nih.gov/21305631/))
- An ionic liquid-based grapeseed oil emulsion increased transdermal penetration by 4.63-fold and improved skin hydration, firmness, elasticity, and facial wrinkles after 28 days of continuous use compared to ordinary emulsion. ([Pharmaceuticals, 2024](https://pubmed.ncbi.nlm.nih.gov/39458914/))

## What reviewers say

Based on a very large amount of data, this product is highly recommended as a gentle introduction to retinol, effectively improving skin texture and reducing fine lines without causing irritation. Users frequently report clearer skin and a more even tone. Some users find the formula too mild for significant anti-aging effects.

- Liked: Great price (mostly mentioned)
- Liked: Very gentle (mostly mentioned)
- Liked: Skin improvements (often mentioned)
- Liked: Clean ingredients (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Too mild (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Texture problems (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Good Molecules Gentle Retinol Cream work for sensitive skin?

Good Molecules Gentle Retinol Cream works moderately well for sensitive skin, as it provides smoothing and soothing benefits with a safe profile, though other products fit it better because they include more moisture-boosting ingredients.
Sources: [Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Which ingredients make this cream a good fit for sensitive skin?

Bakuchiol, retinol, allantoin, and green tea extract help calm and soothe sensitive skin while providing gentle renewal. To be a top fit for sensitive skin, this type of product also needs richer moisturizing ingredients to keep the skin deeply hydrated and comfortable.
Sources: [Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/), [Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/)

### What does Retinol do for sensitive skin?

Retinol is generally too harsh for sensitive skin and may cause stinging, scaling, and irritation. A product for this skin needs gentle ingredients that smooth and calm without causing redness.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Toxicology Letters, 2003](https://pubmed.ncbi.nlm.nih.gov/14615068/)

### What does Bakuchiol do for sensitive skin?

Bakuchiol helps improve barrier function, reduces redness and sensitivity, and softens fine lines in sensitive skin with a very low likelihood of scaling and stinging.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/), [Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/)

### Where does this cream go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your toner and before your moisturizer. A product of this type needs extra hydrating and soothing ingredients to keep sensitive skin calm and comfortable.

### Can I use this cream with vitamin C, and in what order?

You can use this cream and vitamin C in the same routine by applying your vitamin C in the morning and this treatment at night, as using active ingredients at separate times helps prevent extra dryness or redness. A product of this type works best for sensitive skin when it includes plenty of hydrating humectants to keep the skin comfortable.

### How often should I use this cream?

Use this treatment in the evening, starting once a week to let your skin adjust safely. Sensitive skin of this type needs a formula that also provides extra hydrating ingredients to keep the skin comfortable.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Health Science Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41424674/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to cause severe irritation on sensitive skin, but it may occasionally cause breakouts or purging because it features retinol to renew skin cells. A product for this skin type needs extra hydrating and soothing ingredients to keep skin calm and smooth while it adjusts.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [Dr. Ceuracle Tea Tree Purifine 95 Essence](https://lovi.care/skincare/sg/p/dr-ceuracle/tea-tree-purifine-95-essence/for/sensitive-skin) — High fit — S$36.36 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, C13-16 Isoparaffin, Glycerin, Diheptyl Succinate, Heptyl Undecylenate, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Oleate, Propanediol, Vitis Vinifera Seed Oil Grape Seed Oil, Caprylic Capric Triglyceride, Bakuchiol, Tocopherol, Acmella Oleracea Extract, Butylene Glycol, Retinol, Allantoin, Helianthus Annuus Seed Oil Sunflower Seed Oil, Capryloyl Glycerin Sebacic Acid Copolymer, Ethylhexylglycerin, Willow Bark Extract, Camellia Sinensis Leaf Extract, Lilium Candidum Bulb Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/gentle-retinol-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/gentle-retinol-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/gentle-retinol-cream/for/sensitive-skin
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- Australia: https://lovi.care/skincare/au/p/good-molecules/gentle-retinol-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/gentle-retinol-cream/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/gentle-retinol-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/gentle-retinol-cream/for/sensitive-skin