# Goldfaden MD Radical Difference for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Goldfaden MD](https://lovi.care/skincare/sg/brands/goldfaden-md)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate hydration and antioxidant benefits for your normal skin with sensitivity, as sodium hyaluronate and Aspalathus Linearis Extract provide plumping and soothing effects to support redness and irritation.
- Fermented Saccharomyces minerals further aid in barrier repair, contributing to overall skin health and hydration.
- The formula is safe for your skin, with no risks of irritation due to the absence of harsh or prohibited ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Hyaluronate, Aspalathus Linearis Extract, Lactobacillus Acerola Cherry Ferment, Saccharomyces Zinc Ferment, Saccharomyces Magnesium Ferment

## What the research says

- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Ginkgo formulation increased skin moisturization by 27.88% and smoothness by 4.32% while reducing roughness by 0.4% and wrinkles by 4.63%, and significantly improved skin moisturization compared to the tea and rooibos formula. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20412217/))
- The addition of Aspalathus linearis extracts to topical sunscreen formulas containing OMC and BMDBM increased protection factors by up to 50% and protected the filters against photodegradation under radiation doses up to 14.4 standard erythemal doses. ([Photochemical & Photobiological Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/41591727/))
- The combination of fermented and unfermented Aspalathus linearis extracts showed a synergistic photoprotective effect on Normal Human Dermal Fibroblast survival after UVB radiation, which further improved when combined with Polypodium leucotomos extract. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40076948/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Goldfaden MD Radical Difference Serum work for sensitive skin?

Goldfaden MD Radical Difference Serum works reasonably well for sensitive skin by offering moderate hydration and soothing benefits that help calm redness and irritation, though other products fit this skin type better. To work best for sensitive skin, a treatment needs soothing ingredients like niacinamide and snail secretion filtrate to deeply calm irritation while effectively supporting skin health.
Sources: [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Which ingredients make this serum a good fit for sensitive skin?

Sodium hyaluronate and Aspalathus Linearis Extract make this serum a good fit by providing soothing and plumping effects that help with redness and irritation on sensitive skin. Fermented Saccharomyces minerals also help repair the skin barrier, while the lack of harsh ingredients keeps the formula safe from irritation. To fit sensitive skin even better, treatments of this type need calming and strengthening ingredients like niacinamide or snail secretion filtrate.
Sources: [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### What does Roobos Extract do for sensitive skin?

Rooibos extract helps calm sensitive skin by protecting against irritation caused by UV rays and reducing inflammation. It acts as an antioxidant to support skin health.
Sources: [Molecules, 2016](https://pubmed.ncbi.nlm.nih.gov/27706097/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Sensitive skin works best with products that offer soothing ingredients and gentle hydration to support redness and irritation.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying it after your cleanser and soothing toner, and before your moisturizer in your evening routine. This helps calm redness and provides hydration, though sensitive skin requires a product with soothing plant extracts and gentle hydrators to manage potential retinoid irritation better.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use this serum?

Use this treatment in the evening as part of your routine. This product of this type needs soothing ingredients like sodium hyaluronate and antioxidants to calm redness and hydrate sensitive skin safely.
Sources: [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores, cause breakouts or trigger purging on sensitive skin because it is free of heavy, pore-clogging ingredients. A product of this type needs soothing ingredients like sodium hyaluronate and plant extracts to keep sensitive skin calm and hydrated without causing congestion.
Sources: [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — S$50.41 at Amazon
- [Skin1004 Probio-Cica Intensive Ampoule](https://lovi.care/skincare/sg/p/skin1004/probio-cica-intensive-ampoule/for/sensitive-skin) — High fit — S$28.55 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/sensitive-skin) — Average fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — S$30.00 at Amazon
- Soothing Toner: [One Thing Centella Asiatica Extract Toner](https://lovi.care/skincare/sg/p/one-thing/centella-asiatica-extract-toner/for/sensitive-skin) — Superior fit — S$30.07 at Amazon
- Moisturizer with Sun Protection: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/sensitive-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Sodium Hyaluronate, Aspalathus Linearis Extract, Lactobacillus Acerola Cherry Ferment, Saccharomyces Zinc Ferment, Saccharomyces Magnesium Ferment, Saccharomyces Iron Ferment, Saccharomyces Silicon Ferment, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/goldfaden-md/radical-difference/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/goldfaden-md/radical-difference/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/goldfaden-md/radical-difference/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/goldfaden-md/radical-difference/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/goldfaden-md/radical-difference/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/goldfaden-md/radical-difference/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/goldfaden-md/radical-difference/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/goldfaden-md/radical-difference/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/goldfaden-md/radical-difference/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/goldfaden-md/radical-difference/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/goldfaden-md/radical-difference/for/sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/goldfaden-md/radical-difference/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/goldfaden-md/radical-difference/for/sensitive-skin