# Galderma Epiduo Gel for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Galderma](https://lovi.care/skincare/sg/brands/galderma)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your oily, acne-prone skin is provided by adapalene and benzoyl peroxide, which effectively reduce acne lesions and oiliness through their keratolytic and antimicrobial actions.
- Glycerin and proplyene glycol offer hydration and support the skin barrier, ensuring comfort during treatment for your oily skin.
- The formulation is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/sensitive-skin): Caution
- [Acne-prone skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/dark-spots): Low
- [Mature skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/mature-skin): Caution
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Adapalene, Benzoyl Peroxide, Docusate Sodium, Glycerin, Simulgel 600 Pha

## What the research says

- Daily application of adapalene 0.3%/benzoyl peroxide 2.5% gel reduced and prevented atrophic acne scar formation, achieving a total scar count change of -15.5% versus +14.4% for vehicle over 24 weeks in 67 subjects with moderate or severe facial acne. ([American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/))
- Once-daily fixed-dose clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel achieved superior treatment success (52.5%) and greater reductions in inflammatory and noninflammatory lesions compared to vehicle (8.1%) and dyad component gels in participants with moderate-to-severe acne over 12 weeks. ([American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/))
- Tea tree oil nanoemulsion containing adapalene gel demonstrated significantly greater reductions in total, inflammatory, and non-inflammatory acne lesions as well as acne severity index compared to adapalene marketed gel in 100 patients with acne vulgaris over 12 weeks. ([Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34251536/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel achieved significantly greater treatment success and lesion reductions compared to vehicle in participants with moderate-to-severe acne. ([Journal of the American Academy of Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37656094/))
- Treatment with adapalene 0.3%/benzoyl peroxide 2.5% gel for 48 weeks reduced atrophic acne scar counts by 26.9% in subjects with moderate or severe facial acne, while delayed treatment starting at week 24 resulted in a smaller final reduction. ([American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31209851/))
- Adapalene 0.3 %/benzoyl peroxide 2.5 % gel applied once daily for 12 weeks achieved a superior success rate of 33.7% compared to 11.0% for vehicle in subjects with moderate and severe inflammatory acne. ([American Journal of Clinical Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26945741/))
- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Topical benzoyl peroxide may improve acne more effectively than placebo or no treatment, while showing little to no difference compared with adapalene or clindamycin, but with an increased risk of treatment discontinuation due to adverse effects compared to placebo. ([The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/))
- Clindamycin-BPO 2.5% aqueous gel applied once daily provided statistically significant greater efficacy than individual active ingredients and vehicle in reducing inflammatory and noninflammatory lesions and acne severity in 2813 patients with moderate to severe acne vulgaris. ([Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18805603/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Users find this gel effective for stubborn acne, including cystic and hormonal types, with many experiencing significant skin clearing after an initial adjustment. However, the treatment is frequently associated with harsh side effects such as intense burning, dryness, and an initial worsening of acne, necessitating patience and a diligent moisturizing routine.

- Disliked: Intense burning (mostly mentioned)
- Disliked: Severe dryness (mostly mentioned)
- Liked: Clears cystic acne (often mentioned)
- Liked: Prevents breakouts (often mentioned)
- Disliked: Initial acne purge (often mentioned)
- Disliked: Redness and irritation (often mentioned)
- Liked: Fades scars (sometimes noted)
- Liked: Smooths skin texture (sometimes noted)
- Disliked: Bleaches fabrics (sometimes noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Epiduo Gel a great fit for oily acne-prone skin?

Galderma Epiduo Gel is a great fit because adapalene and benzoyl peroxide work to clear breakouts and reduce oiliness, while glycerin helps keep your skin comfortable during treatment.
Sources: [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/), [American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/)

### Which ingredients make this gel a good fit for oily acne-prone skin?

Adapalene and benzoyl peroxide are the key ingredients that make this gel a great fit because they help reduce acne and oiliness. Glycerin and propylene glycol also help by keeping your oily skin comfortable and hydrated during treatment.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### What does Adapalene do for oily acne-prone skin?

Adapalene helps keep pores clear and reduces pimples and oil buildup on acne-prone skin. It also helps calm swelling and prevents new breakouts from forming.
Sources: [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/), [American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/)

### What does Benzoyl Peroxide do for oily acne-prone skin?

Benzoyl peroxide helps improve oily, acne-prone skin by reducing both inflamed and noninflamed breakouts. It works effectively to clear pimples, though it may occasionally cause skin dryness or irritation for some users.
Sources: [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/), [American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/)

### Where does this gel go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps it simple and lowers the chance of sun sensitivity. Glycerin and propylene glycol help keep your oily skin comfortable during use.

### Can I use it with retinol, and in what order?

It is best not to use this treatment in the same routine as retinol, because combining these strong ingredients may easily cause dryness and irritation on oily, acne-prone skin. Instead, apply this gel on its own during your evening routine, and keep retinol for another night.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use it?

Apply this treatment in the evening as part of your routine. Daily application helps clear breakouts and oiliness while keeping your skin comfortable.
Sources: [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Can it clog pores, cause breakouts or purging for oily acne-prone skin?

Galderma Epiduo Gel can cause an initial acne purge for oily acne-prone skin, as its ingredients work to clear breakouts and reduce oiliness. It is also likely to cause severe dryness, intense burning, redness, and irritation.
Sources: [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/), [American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Clean & Clear Persa-Gel 10 Acne Medication](https://lovi.care/skincare/sg/p/clean-and-clear/persa-gel-10/for/oily-acne-prone-skin) — Superior fit — S$25.46 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — S$50.41 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — S$50.41 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sg/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — S$30.40 at Amazon
- Hydrating Toner: [TROIAREUKE H+Cocktail Purifying Ampoule Toner](https://lovi.care/skincare/sg/p/troiareuke/h-cocktail-purifying-ampoule-toner/for/oily-acne-prone-skin) — Superior fit — S$168.51 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/sg/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — S$41.48 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Adapalene, Benzoyl Peroxide, Docusate Sodium, Disodium Edetate, Glycerin, Poloxamer, Propylene Glycol, Water
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/galderma/epiduo-gel/for/oily-acne-prone-skin
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- Italy: https://lovi.care/skincare/it/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/galderma/epiduo-gel/for/oily-acne-prone-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/galderma/epiduo-gel/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/galderma/epiduo-gel/for/oily-acne-prone-skin