# Eighth Day Regenerative Serum for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: [Eighth Day](https://lovi.care/skincare/sg/brands/eighth-day)
Category: [Serums and treatments](https://lovi.care/skincare/sg/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- Offers excellent skin regeneration for your dry and sensitive skin due to multiple peptides like Sh-Oligopeptide-2 and Palmitoyl Tripeptide-5, which improve elasticity and reduce fine lines. Sodium Hyaluronate and Hydrolyzed Hyaluronic Acid provide moderate hydration to address dryness and flakiness.
- Glycerin and Hedychium Coronarium Root Extract further support barrier repair and soothe irritation, making it highly suitable for your dry skin.
- The formulation is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Peptide-Rich Plasma, Sodium Hyaluronate, Niacinamide, Acetyl Glutamine, Manuka Honey

## What the research says

- Supramolecular collagen nanoparticles composed of lactoferrin, recombinant human collagen, and palmitoyl tripeptide-5 improved transdermal efficiency by 69.90% and demonstrated moisturizing, whitening, wrinkle reduction, and firming effects. ([Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical insulin combined with fractional CO2 laser showed no significant difference in efficacy compared to topical PRP combined with fractional CO2 laser for atrophic acne scars in 30 patients. ([Archives of Dermatological Research, 2025](https://pubmed.ncbi.nlm.nih.gov/40167803/))
- Subcision and microneedling combined with topical platelet-rich plasma resulted in significantly greater improvement in scar grading compared to subcision and microneedling alone in patients with atrophic scars. ([Journal of Cutaneous and Aesthetic Surgery, 2024](https://pubmed.ncbi.nlm.nih.gov/38800810/))
- Platelets remain viable for up to 90 days in a refrigerated cosmetic vehicle with demonstrated topical clinical PRP facial benefits, and 20ml and 60ml PRP volumes are equally efficacious. ([Journal of Drugs in Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33346518/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical overnight application of MGO Manuka Honey microemulsion eye cream significantly reduced symptomology, improved tear film stability and lipid layer thickness, and decreased lid margin staining, ocular Demodex, and bacterial load in patients with blepharitis compared to control eyes. ([The Ocular Surface, 2020](https://pubmed.ncbi.nlm.nih.gov/31759183/))
- Optimel 16% manuka honey eye-drops significantly improved symptoms and objective signs in patients with meibomian gland dysfunction compared to baseline after 3 weeks. ([The British Journal of Ophthalmology, 2022](https://pubmed.ncbi.nlm.nih.gov/33419788/))
- The application of Manuka honey and the GENADYNE A4 negative pressure wound therapy system in a 55-year-old woman with extensive phlegmonous and necrotic lesions following traumatic colonic rupture successfully enabled skin autografting and complete wound healing. ([Medical Science Monitor, 2010](https://pubmed.ncbi.nlm.nih.gov/20980964/))

## What reviewers say

This serum is highly praised for its "Peptide-Rich Plasma" technology, which users credit for rapidly improving skin texture, firmness, and radiance. While many describe it as a "holy grail" for anti-aging and hydration, a subset of users feel the high price tag is not justified by the results, which can be subtle for some.

- Disliked: High price (mostly mentioned)
- Liked: Fast absorption (often mentioned)
- Liked: Visible anti-aging (often mentioned)
- Liked: High-tech ingredients (sometimes noted)
- Liked: Hydration (sometimes noted)
- Disliked: Lack of results (sometimes noted)
- Liked: Packaging (rarely noted)
- Disliked: Availability issues (rarely noted)
- Disliked: No acne benefit (rarely noted)
- Disliked: Texture complaints (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Eighth Day Regenerative Serum a great fit for dry sensitive skin?

This serum is a great fit because it offers wonderful skin regeneration for dry and sensitive skin using multiple peptides that improve elasticity and reduce fine lines. Sodium hyaluronate provides moderate hydration to tackle dryness and flakiness, while glycerin and honey soothe irritation and help repair the skin barrier safely.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Sodium hyaluronate and hydrolyzed hyaluronic acid help provide moderate hydration to address dryness and flakiness, while multiple peptides like sh-oligopeptide-2 and palmitoyl tripeptide-5 improve elasticity and smooth fine lines. Additionally, glycerin and hedychium coronarium root extract support barrier repair and soothe irritation without causing harsh side effects.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### What does Peptide-Rich Plasma do for dry sensitive skin?

Platelet-rich plasma helps calm redness and supports skin healing in dry, sensitive skin. It may also improve hydration and barrier function, though dry sensitive skin often needs extra soothing ingredients and rich moisture to fully repair.

### What does Hyaluronic Acid do for dry sensitive skin?

Hyaluronic acid is a great fit for dry, sensitive skin because it brings a large boost in hydration, making the skin feel soft and smooth while improving barrier function. It helps calm tightness and dryness, and is unlikely to cause irritation.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum is used in the evening for your dry and sensitive skin, placed after your toner and before your moisturizer. This timing keeps your routine simple and adds extra safety around sun exposure. A consistent routine helps keep dry skin soft and smooth.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first to help soothe your dry and sensitive skin, followed by your retinol. The formula is safe for your skin with no risks of irritation due to the absence of harsh ingredients.

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after your toner and before your moisturizer. It helps soothe dry, sensitive skin and improves elasticity without irritation, making it safe for daily use.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2025](https://pubmed.ncbi.nlm.nih.gov/39383579/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to clog pores or cause breakouts on dry sensitive skin because its hydrating and soothing ingredients are gentle and safe. It helps keep your skin calm and smooth without heavy oils that typically trigger breakouts.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/sg/p/neogen-dermalogy/real-vitamin-c-serum/for/dry-sensitive-skin) — High fit — S$50.41 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/sg/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-sensitive-skin) — High fit — S$40.09 at Amazon
- [PCA Skin C&E Advanced with Hexylresorcinol and Silymarin](https://lovi.care/skincare/sg/p/pca-skin/c-and-e-advanced/for/dry-sensitive-skin) — High fit — S$192.38 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/sg/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — S$25.06 at Amazon
- Soothing Toner: [Mario Badescu Facial Spray with Aloe, Chamomile and Lavender](https://lovi.care/skincare/sg/p/mario-badescu/facial-spray-with-aloe-chamomile-and-lavender/for/dry-sensitive-skin) — High fit — S$34.52 at Amazon
- Moisturizer with Sun Protection: [Dr.G Green Mild Up Sun+](https://lovi.care/skincare/sg/p/dr-g/green-mild-up-sun/for/dry-sensitive-skin) — Superior fit — S$59.06 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Water, Pentylene Glycol, Peptide-Rich Plasma, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Acetyl Glutamine, Sodium Hyaluronate, Lysine Hcl, Alanine, Histidine Hcl, Arginine, Serine, Proline, Glutamic Acid, Threonine, Valine, Leucine, Glycine, Isoleucine, Phenylalanine, Taurine, Glycerin, Hedychium Coronarium Root Extract, Tripeptide-1, Polygonum Aviculare Extract, Honey, Nonapeptide-1, Acetyl Heptapeptide-4, Phytosphingosine, Sea Whip Extract, Niacinamide, Hydrolyzed Hyaluronic Acid, Aminobutyric Acid, Adenosine, Thioctic Acid, Glycolic Acid, Bacillus Soybean Folic Acid Extract Ferment, Polysorbate 20, Allantoin, Caprylyl Glycol, Lecithin, Butylene Glycol, 1,2-Hexanediol, Dextran, Phenoxyethanol, Ethylhexylglycerin, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/eighth-day/regenerative-serum/for/dry-sensitive-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/eighth-day/regenerative-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/eighth-day/regenerative-serum/for/dry-sensitive-skin