Dr. Dennis Gross Hyaluronic Marine Meltaway Cleanser for mature skin

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Questions and answers

What the research says

• A novel moisturizer containing saccharide isomerate accelerates skin barrier recovery, improves hydration, reduces erythema, and alleviates discomfort compared to a control moisturizer following intense pulsed light treatment in subjects with skin aging.

  The Journal of Dermatological Treatment, 2025

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events.

  Lasers in Medical Science, 2025

• Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.

  Dermatologic Therapy, 2022

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• Purified polysaccharides from kiwi fruit stimulated cell proliferation up to 30%, mitochondrial activity by nearly 25% in human keratinocytes, increased proliferation and ATP synthesis in fibroblasts, and doubled collagen synthesis in three-dimensional skin equivalents compared to controls.

  Journal of Cellular Physiology, 2005

• Ethanolic extract of Actinidia chinensis Planch ameliorated UVB-mediated photoaging by reducing wrinkle formation, epidermal thickening, and collagen loss while decreasing reactive oxygen species overproduction and regulating the AKT pathway in NIH-3T3 cells and SKH-1 hairless mice compared to UVB irradiation alone.

  Antioxidants, 2024

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

  Journal of Drugs in Dermatology, 2012

Why other cleansers fit mature skin better

• Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.

  International Journal of Biological Macromolecules, 2024

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• Camellia japonica oil activated the human COL1A2 promoter, induced type I procollagen synthesis, inhibited matrix metalloproteinase-1 activity, and reduced trans-epidermal water loss without inducing adverse reactions in human skin.

  Journal of Ethnopharmacology, 2007

Ingredients

Water, Ethylhexyl Palmitate, Neopentyl Glycol Diheptanoate, Butylene Glycol, Isododecane, Cetearyl Isononanoate, Glycerin, Sodium Hyaluronate, Saccharide Isomerate, Caulerpa Lentillifera Extract, Actinidia Chinensis Fruit Extract, Aloe Barbadensis Leaf Juice, Phytic Acid, Citrus Aurantium Dulcis Peel Extract, Grapefruit Peel Extract, Vanilla Planifolia Fruit Extract, Cucumis Melo Fruit Extract, Triethyl Citrate, Lactic Acid, Copper Pca, Citric Acid, Sodium Citrate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.