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Dermol 500 Lotion for combination skin

Caution

  • CautionCombination Skin Fit
  • AverageEffectiveness
  • RiskySafety

A poor match for combination skin; the moisturizers alongside fit it better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

How to apply

  • Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
  • Apply this moisturizer after your cleanser and toner, right before your morning SPF.
  • Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
  • Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
  • Avoid the eye area when applying the moisturizer. Do a patch test before your first use.

People Say

★4.9Overall rating based on 1000+ reviews

It is celebrated for its versatility as both a leave-on moisturizer and a soap substitute, providing rapid relief from itching and preventing secondary infections due to its antimicrobial properties.

Highlights

  • Versatile application Mostly Mentioned
    • “Soap substitute”
    • “shower gel”
    • “leave-on moisturizer”
  • Excellent texture Often Mentioned
    • “Non-greasy”
    • “absorbs quickly”
    • “light consistency”
  • Hand care Often Mentioned
    • “Heals cracked hands”
    • “non-drying wash”
    • “gentle cleanser”
  • Rapid itch relief Often Mentioned
    • “Soothes irritation”
    • “stops scratching”
    • “calms redness”
  • Antimicrobial benefits Sometimes Noted
    • “Prevents infection”
    • “clears folliculitis”
    • “kills bacteria”
  • Adverse reactions Rarely Noted
    • “Facial rash”
    • “stinging sensation”
    • “increased redness”
  • Insufficient for dryness Rarely Noted
    • “Too thin”
    • “not rich enough”
    • “requires thicker cream”
  • Medicinal scent Rarely Noted
    • “Weird smell”
    • “chemical odor”
    • “unpleasant scent”
  • Packaging issues Rarely Noted
    • “Pump faults”
    • “hard to empty”
    • “broken dispenser”
  • Texture dislike Rarely Noted
    • “Too runny”
    • “watery consistency”
    • “not lotion-like”

Sources: lovi.care, pharmica.co.uk, medino.com, chemist-4-u.com, amazon.com, chemistdirect.co.uk, and more

Questions and answers

Why does Lovi advise caution with Dermol 500 Lotion for combination skin?

This lotion may exacerbate oiliness and clog pores on combination skin because it contains liquid paraffin and isopropyl myristate. A product for this skin needs soothing and hydrating ingredients like aloe and Centella Asiatica that balance dry and oily areas without clogging pores.

Cutaneous and Ocular Toxicology, 2007

Which ingredients make this lotion a poor fit for combination skin?

Liquid paraffin and isopropyl myristate make this lotion a poor fit because they hydrate the skin but may increase oiliness and clog pores. A moisturizing treatment for combination skin needs soothing and hydrating ingredients like aloe and Centella Asiatica that balance dry and oily areas without clogging pores.

Cutaneous and Ocular Toxicology, 2007

What does Benzalkonium Chloride do for combination skin?

Benzalkonium chloride is unlikely to suit combination skin because it is a known skin irritant and allergen that may cause redness or rashes. A product for this skin needs gentle, soothing ingredients that calm irritation and protect the skin barrier.

Dermatosen in Beruf und Umwelt. Occupation and Environment, 1985

What does Chlorhexidine Dihydrochloride do for combination skin?

Chlorhexidine Dihydrochloride is an antiseptic that helps reduce bacteria on the skin, but a product for combination skin also needs balanced hydrators and lightweight ingredients that care for both dry and oily areas without clogging pores.

MSphere, 2025The Journal of Investigative Dermatology, 2018

Where does this lotion go in a skincare routine for combination skin?

This lotion may not be the best fit for your combination skin because its heavy ingredients can increase oiliness and clog pores. To properly care for combination skin, a moisturizer needs lightweight hydrators that balance moisture without feeling heavy or causing breakouts.

Cutaneous and Ocular Toxicology, 2007

Can I use it with retinol, and in what order?

You should exercise caution when using this lotion with retinol on combination skin, as its heavy ingredients may clog pores and increase oiliness in certain areas. To care for combination skin properly, you instead need a lightweight moisturizer with ceramides and soothing ingredients that hydrates dry zones without triggering breakouts.

Cutaneous and Ocular Toxicology, 2007Journal of Drugs in Dermatology, 2023

How often should I use this lotion?

This lotion is a poor match for combination skin because its heavy oils may make oily areas slicker and clog pores. To properly care for combination skin, a moisturizer needs light, oil-free hydrators that soften the skin without adding extra shine or clogging pores.

Can it clog pores, cause breakouts or purging for combination skin?

Yes, this lotion may clog pores and cause breakouts on combination skin because ingredients like isopropyl myristate and liquid paraffin tend to trap oil in the skin. To care for combination skin safely, a product of this type needs lightweight hydrators and non-pore-clogging ingredients that balance dry areas without making oily zones greasy.

Cutaneous and Ocular Toxicology, 2007

Can I use this lotion around the eyes or on my body?

This lotion is a poor match for your combination skin because its heavier oils may clog pores and increase oiliness. For the thin skin around the eyes and on the body, a moisturizing treatment of this type needs lightweight hydrators and gentle, non-clogging ingredients that nourish without feeling heavy.

Surgical and Radiologic Anatomy, 2002Cutaneous and Ocular Toxicology, 2007

Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • Topical application of isopropyl palmitate, isopropyl myristate, butyl stearate, isopropyl isostearate, decyl oleate, isostearyl neopentanoate, isocetyl stearate, myristle myristate, and cocoa butter produced comedone formation in the rabbit external ear canal.

    Cutaneous and Ocular Toxicology, 2007
  • A non-alcoholic benzalkonium chloride hand sanitizer demonstrated antibacterial activity against nine out of eleven bacterial strains and caused no skin irritation or redness in ten participants compared to alcohol-based hand gels.

    Saudi Pharmaceutical Journal, 2021
  • Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.

    Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
  • Topical application of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and anti-inflammatory agents after ultrasound scalpel-assisted hemorrhoidectomy reduced pain and itching while accelerating complete wound healing at 4 weeks compared to washing with warm water alone in adult patients.

    Annals of Coloproctology, 2024
  • Topical therapy with 4% chlorhexidine digluconate products resolved clinical signs in all dogs with superficial pyoderma, including those with meticillin-resistant strains, showing comparable efficacy to systemic amoxicillin-clavulanic acid.

    Veterinary Dermatology, 2015
  • Repeated application of concentrated water-in-oil emulsions over four weeks caused no skin irritation, positively affected skin properties, and delivered almost 50% of the applied fluorescein sodium, with isopropyl myristate showing superior penetration performance compared to liquid paraffin in healthy volunteers.

    International Journal of Pharmaceutics, 2019
  • Increasing the softness of pressure-sensitive adhesives using isopropyl myristate decreased pain and stripped corneocytes during removal without significantly changing human skin dermal peeling force.

    Skin Research and Technology, 2007
  • A modern cold cream formulation using a self-emulsionable excipient with isopropyl myristate shows improved preparation ease, stability, rheological qualities, and moisture and emollient power compared to traditional cerates.

    Bollettino Chimico Farmaceutico, 1996

Ingredients

Benzalkonium Chloride, Chlorhexidine Dihydrochloride, Liquid Paraffin, Isopropyl Myristate, Cetostearyl Alcohol, Cetomacrogol 1000, Phenoxyethanol, Water

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

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