# CLIV PHA Mild Enzyme Powder for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Singapore.

Brand: CLIV
Category: [Exfoliants](https://lovi.care/skincare/sg/best/exfoliators)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few products fit it even better.

## Why this fit

- Offers moderate exfoliation for your wrinkles and fine lines, as papain and bromelain gently promote skin renewal, while sodium hyaluronate and glycerin provide essential hydration for your normal skin.
- The Lactobacillus Punica Granatum Extract Fruit Ferment and Portulaca Oleracea Extract offer additional antioxidant and soothing benefits, complementing the primary exfoliating action.
- The formula is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/oily-acne-prone-skin): High

## Key ingredients

Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Facial masks containing low-temperature extracted Portulaca oleracea protect sensitive skin from photothermal stimulation and improve skin barrier function during photorejuvenation. ([Cutaneous and Ocular Toxicology, 2025](https://pubmed.ncbi.nlm.nih.gov/41182319/))
- Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG. ([Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))
- Oral bromelain slightly reduced pain compared to controls (mean difference -0.27) and topical bromelain reduced time to complete debridement by 6.89 days, with no major health risks reported. ([Nutrition and Health, 2023](https://pubmed.ncbi.nlm.nih.gov/37157782/))
- An upcycled pineapple leaf fibre crosspolymer forms a physical barrier that protects against environmental aggressors while providing antioxidant, anti-inflammatory, antipollution, UV protection, hydration, and hair benefits. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41524117/))
- A coaxial electrospun core-shell nanofiber scaffold delivering bromelain and salvianolic acid B demonstrated sustained drug release, in vitro endothelial cell migration, increased capillary formation in an in ovo assay, and in vivo efficacy for skin regeneration and wound healing. ([Biomedical Materials, 2017](https://pubmed.ncbi.nlm.nih.gov/28580904/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects. ([The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Based on limited data, this enzyme powder is highly praised for its ability to gently exfoliate and deeply cleanse the skin without causing irritation or dryness. Users with sensitive and mixed skin types report that it effectively removes impurities and makeup, leaving the skin feeling exceptionally smooth, soft, and hydrated.

- Liked: Non-stripping cleanse (mostly mentioned)
- Liked: Gentle exfoliation (often mentioned)
- Liked: Skin texture improvement (often mentioned)
- Disliked: Limited availability (often mentioned)
- Liked: Suitable for sensitive skin (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Messy application (rarely noted)
- Disliked: Potential irritants (rarely noted)

## How to apply

- Use your enzyme powder exfoliant as part of your weekly routine. Start by using it once a week and increase frequency if your skin feels fine.
- Apply this product after cleansing and before using a hydrating toner. Follow with your usual serum and moisturizer.
- Mix the enzyme powder with a little water in your hands to create a paste. Gently massage it onto your face without scrubbing hard.
- Apply the exfoliant on clean, slightly damp skin for the best results. This helps the powder activate properly.
- Avoid the sensitive eye area and do a patch test before your first use. Always use SPF during the day while using exfoliating products.
- Video: https://storage.pora.ai/767f9b79c33b777aa28f84f66e309d62.mp4

## Questions and answers

### What makes CLIV PHA Mild Enzyme Powder a great fit for mature skin?

CLIV PHA Mild Enzyme Powder is a great fit for mature skin because papain and bromelain gently smooth wrinkles and fine lines through moderate exfoliation. At the same time, sodium hyaluronate and glycerin keep skin hydrated, while added plant extracts help calm and protect your face without causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which ingredients make this exfoliant a good fit for mature skin?

Papain and bromelain gently promote skin renewal to help smooth wrinkles and fine lines on mature skin. Sodium hyaluronate and glycerin add essential hydration, while plant extracts calm the skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Papain do for mature skin?

Papain gently exfoliates the outer layer of skin by breaking down surface proteins, which helps reveal smoother and fresher skin. This gentle shedding process may improve skin texture and reduce the look of dullness in mature skin.
Sources: [International Journal of Cosmetic Science, 2022](https://pubmed.ncbi.nlm.nih.gov/35892222/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34897928/)

### What does Bromelain do for mature skin?

Bromelain helps smooth mature skin by acting as an exfoliating agent to clear away dead surface layers and improve overall texture. Studies show that proteolytic enzymes like bromelain can successfully exfoliate the skin and enhance its cosmetic characteristics with a low risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34897928/)

### Where does this exfoliant go in a skincare routine for mature skin?

This exfoliant goes in your weekly routine, and you can start using it once a week as part of your evening steps. People who tolerate it well and see good results may carefully use it more often.

### Can I use this exfoliant with retinol, and in what order?

You can use this exfoliant in your weekly routine, but avoid applying it on the same nights you use retinol to keep your skin calm and prevent irritation. Use the enzyme powder after cleansing on your designated weekly treatment night, and follow up with a nourishing mask and moisturizer to keep your skin soft and hydrated.

### How often should I use this exfoliant?

You can start using this enzyme powder once a week as part of your routine. If your mature skin tolerates it well and you see good results, you can carefully use it more often.

### Can this exfoliant clog pores, cause breakouts or purging for mature skin?

This exfoliant is unlikely to clog pores, cause breakouts, or lead to purging on mature skin. Its gentle ingredients promote skin renewal safely while providing soothing and hydrating benefits.

### Is this exfoliant fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Eminence Organic Skin Care Strawberry Rhubarb Dermafoliant](https://lovi.care/skincare/sg/p/eminence-organic-skin-care/strawberry-rhubarb-dermafoliant/for/mature-skin) — Average fit — S$50.74 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sg/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — S$30.00 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/sg/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — S$41.07 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/sg/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — S$110.01 at Amazon

## Where to buy

No store in Singapore has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Sodium Palmitate, Diglycerin, Allantoin, Maltodextrin, Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Lauryl Betaine, Sodium Chloride, Lactobacillus Punica Granatum Extract Fruit Ferment, Portulaca Oleracea Extract, Rosa Multiflora Fruit Extract, Ceratonia Siliqua Fruit Extract, Chenopodium Quinoa Seed Extract, Lens Esculenta Fruit Extract, Nelumbo Nucifera Seed Extract, Glycerin, 1,2-Hexanediol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cliv/pha-mild-enzyme-powder/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/cliv/pha-mild-enzyme-powder/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/mature-skin
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- Netherlands: https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/mature-skin
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- Canada: https://lovi.care/skincare/ca/p/cliv/pha-mild-enzyme-powder/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/cliv/pha-mild-enzyme-powder/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/mature-skin (this page)
- Saudi Arabia: https://lovi.care/skincare/sa/p/cliv/pha-mild-enzyme-powder/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cliv/pha-mild-enzyme-powder/for/mature-skin